ClinVar Miner

List of variants in gene TP53 reported as uncertain significance by Quest Diagnostics Nichols Institute San Juan Capistrano

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Gene type:
ClinVar version:
Total variants: 58
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HGVS dbSNP gnomAD frequency
NM_000546.6(TP53):c.869G>A (p.Arg290His) rs55819519 0.00014
NM_000546.6(TP53):c.460G>A (p.Gly154Ser) rs137852789 0.00004
NM_000546.6(TP53):c.554G>A (p.Ser185Asn) rs150607408 0.00004
NM_000546.6(TP53):c.642T>G (p.His214Gln) rs587781386 0.00004
NM_000546.6(TP53):c.868C>T (p.Arg290Cys) rs770374782 0.00004
NM_000546.6(TP53):c.214C>G (p.Pro72Ala) rs587782769 0.00003
NM_000546.6(TP53):c.329G>A (p.Arg110His) rs11540654 0.00003
NM_000546.6(TP53):c.467G>A (p.Arg156His) rs371524413 0.00003
NM_000546.6(TP53):c.1000G>C (p.Gly334Arg) rs730882028 0.00001
NM_000546.6(TP53):c.1066G>C (p.Gly356Arg) rs766786605 0.00001
NM_000546.6(TP53):c.1151T>C (p.Met384Thr) rs1060501196 0.00001
NM_000546.6(TP53):c.250G>A (p.Ala84Thr) rs587781307 0.00001
NM_000546.6(TP53):c.346T>G (p.Ser116Ala) rs989692988 0.00001
NM_000546.6(TP53):c.376-2dup rs751253294 0.00001
NM_000546.6(TP53):c.393C>A (p.Asn131Lys) rs769270327 0.00001
NM_000546.6(TP53):c.399G>A (p.Met133Ile) rs1064795139 0.00001
NM_000546.6(TP53):c.530C>T (p.Pro177Leu) rs751477326 0.00001
NM_000546.6(TP53):c.556G>A (p.Asp186Asn) rs1060501206 0.00001
NM_000546.6(TP53):c.572C>G (p.Pro191Arg) rs587778718 0.00001
NM_000546.6(TP53):c.587G>A (p.Arg196Gln) rs483352697 0.00001
NM_000546.6(TP53):c.604C>T (p.Arg202Cys) rs587780072 0.00001
NM_000546.6(TP53):c.672+6G>T rs766856111 0.00001
NM_000546.6(TP53):c.760A>G (p.Ile254Val) rs746601313 0.00001
NM_000546.6(TP53):c.848G>A (p.Arg283His) rs371409680 0.00001
NM_000546.6(TP53):c.907A>G (p.Ser303Gly) rs587782391 0.00001
NM_000546.6(TP53):c.949C>A (p.Gln317Lys) rs764735889 0.00001
NM_000546.6(TP53):c.-10G>T rs1407651518
NM_000546.6(TP53):c.-5C>T rs1555527034
NM_000546.6(TP53):c.1016A>G (p.Glu339Gly) rs1237829645
NM_000546.6(TP53):c.1079G>T (p.Gly360Val) rs35993958
NM_000546.6(TP53):c.1115A>C (p.Lys372Thr) rs876658876
NM_000546.6(TP53):c.1129A>G (p.Thr377Ala) rs774269719
NM_000546.6(TP53):c.1136G>T (p.Arg379Leu) rs863224682
NM_000546.6(TP53):c.1140dup (p.Lys381Ter) rs1567540295
NM_000546.6(TP53):c.1147C>T (p.Leu383Phe) rs150842067
NM_000546.6(TP53):c.11C>T (p.Pro4Leu) rs878854064
NM_000546.6(TP53):c.256G>A (p.Ala86Thr) rs587782148
NM_000546.6(TP53):c.303A>G (p.Lys101=) rs878854069
NM_000546.6(TP53):c.326T>C (p.Phe109Ser) rs1064796722
NM_000546.6(TP53):c.388C>G (p.Leu130Val) rs863224683
NM_000546.6(TP53):c.446C>T (p.Ser149Phe) rs1555526214
NM_000546.6(TP53):c.464C>A (p.Thr155Asn) rs786202752
NM_000546.6(TP53):c.509C>G (p.Thr170Arg) rs779000871
NM_000546.6(TP53):c.559+8G>A rs775915220
NM_000546.6(TP53):c.560-9T>A rs794727781
NM_000546.6(TP53):c.617T>C (p.Leu206Ser) rs1555525804
NM_000546.6(TP53):c.688A>G (p.Thr230Ala) rs1597365431
NM_000546.6(TP53):c.694A>C (p.Ile232Leu) rs1555525562
NM_000546.6(TP53):c.75-8del rs1567557765
NM_000546.6(TP53):c.752T>C (p.Ile251Thr) rs730882027
NM_000546.6(TP53):c.79C>A (p.Pro27Thr) rs922736614
NM_000546.6(TP53):c.807C>G (p.Ser269Arg)
NM_000546.6(TP53):c.819T>C (p.Arg273=) rs1567547965
NM_000546.6(TP53):c.892G>A (p.Glu298Lys) rs201744589
NM_000546.6(TP53):c.917G>A (p.Arg306Gln) rs1048095040
NM_000546.6(TP53):c.919+10C>G
NM_000546.6(TP53):c.924G>C (p.Leu308=) rs786202546
NM_000546.6(TP53):c.997C>T (p.Arg333Cys) rs769934890

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