List of variants in gene MSH2 reported as likely benign by International Society for Gastrointestinal Hereditary Tumours (InSiGHT)

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 33

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HGVS	dbSNP	gnomAD frequency
NM_000251.3(MSH2):c.984C>T (p.Ala328=)	rs4987189	0.00495
NM_000251.3(MSH2):c.*226A>G	rs17225060	0.00201
NM_000251.3(MSH2):c.1737A>G (p.Lys579=)	rs61756467	0.00138
NM_000251.3(MSH2):c.1680T>C (p.Asn560=)	rs200056411	0.00043
NM_000251.3(MSH2):c.2154A>G (p.Gln718=)	rs63750810	0.00033
NM_000251.3(MSH2):c.471C>A (p.Gly157=)	rs61756463	0.00029
NM_000251.3(MSH2):c.1255C>A (p.Gln419Lys)	rs63750006	0.00019
NM_000251.3(MSH2):c.1276+47T>A	rs148018406	0.00019
NM_000251.3(MSH2):c.138C>G (p.His46Gln)	rs33946261	0.00019
NM_000251.3(MSH2):c.1730T>C (p.Ile577Thr)	rs63749910	0.00018
NM_000251.3(MSH2):c.505A>G (p.Ile169Val)	rs63750716	0.00013
NM_000251.3(MSH2):c.*221G>T	rs587779060	0.00010
NM_000251.3(MSH2):c.1488A>G (p.Leu496=)	rs267607960	0.00008
NM_000251.3(MSH2):c.2500G>A (p.Ala834Thr)	rs63750757	0.00008
NM_000251.3(MSH2):c.4G>A (p.Ala2Thr)	rs63750466	0.00008
NM_000251.3(MSH2):c.944G>T (p.Gly315Val)	rs202026056	0.00006
NM_000251.3(MSH2):c.287G>A (p.Arg96His)	rs63750002	0.00004
NM_000251.3(MSH2):c.304G>A (p.Val102Ile)	rs193922373	0.00002
NM_000251.3(MSH2):c.1344C>T (p.Ser448=)	rs1010360604	0.00001
NM_000251.3(MSH2):c.164G>A (p.Arg55Gln)	rs748196422	0.00001
NM_000251.3(MSH2):c.213A>G (p.Gly71=)	rs878853808	0.00001
NM_000251.3(MSH2):c.2579C>T (p.Ser860Leu)	rs63750849	0.00001
NM_000251.3(MSH2):c.972G>A (p.Gln324=)	rs63750505	0.00001
NM_000251.3(MSH2):c.1602T>A (p.Arg534=)	rs267607965
NM_000251.3(MSH2):c.1661+6C>T	rs267607973
NM_000251.3(MSH2):c.1755T>C (p.Ser585=)	rs63750112
NM_000251.3(MSH2):c.1760-110_1760-108dup	rs587779109
NM_000251.3(MSH2):c.2005+8dup	rs267607992
NM_000251.3(MSH2):c.2139G>C (p.Gly713=)	rs63750003
NM_000251.3(MSH2):c.2583A>G (p.Gln861=)	rs63751093
NM_000251.3(MSH2):c.2681T>G (p.Met894Arg)	rs1558526026
NM_000251.3(MSH2):c.2714C>G (p.Thr905Arg)	rs267608022
NM_000251.3(MSH2):c.6G>T (p.Ala2=)	rs368270856

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