List of variants in gene MSH6 reported as likely benign by International Society for Gastrointestinal Hereditary Tumours (InSiGHT)

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 30

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HGVS	dbSNP	gnomAD frequency
NM_000179.3(MSH6):c.3557-40T>A	rs189436849	0.00587
NM_000179.3(MSH6):c.457+13A>G	rs1800933	0.00434
NM_000179.3(MSH6):c.3911G>A (p.Arg1304Lys)	rs34625968	0.00253
NM_000179.3(MSH6):c.1526T>C (p.Val509Ala)	rs63751005	0.00067
NM_000179.3(MSH6):c.1508C>G (p.Ser503Cys)	rs63750897	0.00059
NM_000179.3(MSH6):c.3488A>T (p.Glu1163Val)	rs63750252	0.00032
NM_000179.3(MSH6):c.3217C>T (p.Pro1073Ser)	rs142254875	0.00028
NM_000179.3(MSH6):c.3160A>T (p.Ile1054Phe)	rs267608075	0.00016
NM_000179.3(MSH6):c.2398G>C (p.Val800Leu)	rs61748083	0.00014
NM_000179.3(MSH6):c.59C>T (p.Ala20Val)	rs63750664	0.00013
NM_000179.3(MSH6):c.1875C>T (p.Ser625=)	rs63749886	0.00010
NM_000179.3(MSH6):c.660A>C (p.Glu220Asp)	rs1800938	0.00009
NM_000179.3(MSH6):c.1019T>C (p.Phe340Ser)	rs61753793	0.00006
NM_000179.3(MSH6):c.3986C>T (p.Ser1329Leu)	rs199594809	0.00006
NM_000179.3(MSH6):c.2319C>T (p.Leu773=)	rs63749895	0.00003
NM_000179.3(MSH6):c.1403G>A (p.Arg468His)	rs41295268	0.00001
NM_000179.3(MSH6):c.1487G>A (p.Cys496Tyr)	rs764593111	0.00001
NM_000179.3(MSH6):c.161G>C (p.Gly54Ala)	rs63751098	0.00001
NM_000179.3(MSH6):c.194C>T (p.Ser65Leu)	rs41294984	0.00001
NM_000179.3(MSH6):c.241G>A (p.Ala81Thr)	rs587779239	0.00001
NM_000179.3(MSH6):c.2661T>G (p.Leu887=)	rs267608069	0.00001
NM_000179.3(MSH6):c.2765G>A (p.Arg922Gln)	rs752839086	0.00001
MSH6:c.3647-51_3647-35del17	rs267607687
NM_000179.3(MSH6):c.1667A>T (p.Tyr556Phe)	rs63751312
NM_000179.3(MSH6):c.1770C>T (p.Pro590=)	rs267608070
NM_000179.3(MSH6):c.2319C>A (p.Leu773=)	rs63749895
NM_000179.3(MSH6):c.3207G>T (p.Gly1069=)	rs267608074
NM_000179.3(MSH6):c.4001+2TAAC[2]	rs267608132
NM_000179.3(MSH6):c.4002-10del	rs59056100
NM_000179.3(MSH6):c.4068_4071dup (p.Lys1358delinsAspTer)	rs55740729

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