List of variants in gene MLH1 reported as uncertain significance by Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 34

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HGVS	dbSNP	gnomAD frequency
NM_000249.4(MLH1):c.1964T>C (p.Ile655Thr)	rs63751225	0.00010
NM_000249.4(MLH1):c.1558+5G>A	rs199935667	0.00008
NM_000249.4(MLH1):c.1013A>G (p.Asn338Ser)	rs63751467	0.00006
NM_000249.4(MLH1):c.2174G>A (p.Arg725His)	rs566928243	0.00006
NM_000249.4(MLH1):c.453G>A (p.Thr151=)	rs369521379	0.00006
NM_000249.4(MLH1):c.955G>A (p.Glu319Lys)	rs63750796	0.00006
NM_000249.4(MLH1):c.1937A>G (p.Tyr646Cys)	rs35045067	0.00005
NM_000249.4(MLH1):c.1565G>A (p.Arg522Gln)	rs63751630	0.00004
NM_000249.4(MLH1):c.1633A>G (p.Thr545Ala)	rs267607840	0.00004
NM_000249.4(MLH1):c.794G>A (p.Arg265His)	rs63751448	0.00004
NM_000249.4(MLH1):c.539T>G (p.Val180Gly)	rs63750102	0.00003
NM_000249.4(MLH1):c.991G>A (p.Glu331Lys)	rs550914672	0.00003
NM_000249.4(MLH1):c.226G>A (p.Val76Ile)	rs878853788	0.00002
NM_000249.4(MLH1):c.595G>C (p.Glu199Gln)	rs63749887	0.00002
NM_000249.4(MLH1):c.-11C>T	rs776898290	0.00001
NM_000249.4(MLH1):c.1451A>G (p.Asp484Gly)	rs876659795	0.00001
NM_000249.4(MLH1):c.1460G>A (p.Arg487Gln)	rs587778917	0.00001
NM_000249.4(MLH1):c.1775G>C (p.Ser592Thr)	rs587782621	0.00001
NM_000249.4(MLH1):c.541G>A (p.Gly181Ser)	rs1064795694	0.00001
NM_000249.4(MLH1):c.622C>T (p.Pro208Ser)	rs587781509	0.00001
NM_000249.4(MLH1):c.739T>G (p.Ser247Ala)	rs63750948	0.00001
NM_000249.4(MLH1):c.848A>G (p.Tyr283Cys)	rs201931669	0.00001
NM_000249.4(MLH1):c.943C>T (p.His315Tyr)	rs151119913	0.00001
NM_000249.4(MLH1):c.1655CCA[1] (p.Thr553del)	rs63751641
NM_000249.4(MLH1):c.1783A>T (p.Ser595Cys)	rs876658763
NM_000249.4(MLH1):c.1873T>C (p.Tyr625His)	rs1413395234
NM_000249.4(MLH1):c.2105G>C (p.Ser702Thr)	rs973343336
NM_000249.4(MLH1):c.2110G>C (p.Val704Leu)	rs587781811
NM_000249.4(MLH1):c.2173_2174delinsTT
NM_000249.4(MLH1):c.242C>G (p.Thr81Ser)	rs63751069
NM_000249.4(MLH1):c.299G>T (p.Arg100Leu)	rs63750266
NM_000249.4(MLH1):c.362A>T (p.Asp121Val)	rs730881735
NM_000249.4(MLH1):c.696_698del (p.Cys233del)	rs1575480253
NM_000249.4(MLH1):c.91_92delinsTG

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