List of variants in gene POLE reported as benign by Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 37

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HGVS	dbSNP	gnomAD frequency
NM_006231.4(POLE):c.1226+45C>T	rs5744761	0.07418
NM_006231.4(POLE):c.2469-15G>A	rs5744833	0.07057
NM_006231.4(POLE):c.4445-33C>T	rs5744942	0.05559
NM_006231.4(POLE):c.3379-5T>C	rs5744886	0.02670
NM_006231.4(POLE):c.3126G>A (p.Lys1042=)	rs5744856	0.02344
NM_006231.4(POLE):c.4290+5C>T	rs5744936	0.02053
NM_006231.4(POLE):c.2340G>A (p.Ser780=)	rs5744822	0.02051
NM_006231.4(POLE):c.2320-13A>G	rs75329753	0.01853
NM_006231.4(POLE):c.2550C>T (p.Ile850=)	rs5744834	0.01438
NM_006231.4(POLE):c.6418G>A (p.Glu2140Lys)	rs5745066	0.01416
NM_006231.4(POLE):c.5678+4C>T	rs5744973	0.01405
NM_006231.4(POLE):c.6330+18C>T	rs5745024	0.01405
NM_006231.4(POLE):c.91G>T (p.Ala31Ser)	rs34047482	0.01320
NM_006231.4(POLE):c.6330+19G>A	rs5745025	0.01268
NM_006231.4(POLE):c.2174-8G>A	rs117409343	0.01137
NM_006231.4(POLE):c.5811+46G>A	rs5744992	0.01076
NM_006231.4(POLE):c.2928C>T (p.Arg976=)	rs5744845	0.00958
NM_006231.4(POLE):c.1795-22C>T	rs5744797	0.00955
NM_006231.4(POLE):c.5583A>C (p.Ser1861=)	rs5744972	0.00949
NM_006231.4(POLE):c.3265_3275+15dup	rs1555225627	0.00913
NM_006231.4(POLE):c.5804G>A (p.Cys1935Tyr)	rs5744991	0.00898
NM_006231.4(POLE):c.1007A>G (p.Asn336Ser)	rs5744760	0.00805
NM_006231.4(POLE):c.1470C>T (p.Asp490=)	rs5744777	0.00679
NM_006231.4(POLE):c.776G>A (p.Arg259His)	rs61732929	0.00604
NM_006231.4(POLE):c.6494G>A (p.Arg2165His)	rs5745068	0.00550
NM_006231.4(POLE):c.1359+9G>A	rs75135381	0.00498
NM_006231.4(POLE):c.6817A>T (p.Thr2273Ser)	rs73481453	0.00444
NM_006231.4(POLE):c.779G>A (p.Arg260Gln)	rs5744752	0.00312
NM_006231.4(POLE):c.5334C>T (p.Ala1778=)	rs11146986	0.00205
NM_006231.4(POLE):c.5124C>T (p.Phe1708=)	rs114891564	0.00149
NM_006231.4(POLE):c.1323G>A (p.Pro441=)	rs116573514	0.00106
NM_006231.4(POLE):c.1794+35_1794+36del	rs368632925
NM_006231.4(POLE):c.2083T>A (p.Phe695Ile)	rs5744799
NM_006231.4(POLE):c.2089C>T (p.Pro697Ser)	rs5744800
NM_006231.4(POLE):c.2865-4dup	rs369732588
NM_006231.4(POLE):c.4552-10G>T	rs5744946
NM_006231.4(POLE):c.5378+23G>C

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