List of variants in gene BRCA1 reported as benign by Color Diagnostics, LLC DBA Color Health

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 99

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HGVS	dbSNP	gnomAD frequency
NM_007294.4(BRCA1):c.2082C>T (p.Ser694=)	rs1799949	0.30810
NM_007294.4(BRCA1):c.4987-68A>G	rs8176234	0.30809
NM_007294.4(BRCA1):c.5152+66G>A	rs3092994	0.30314
NM_007294.4(BRCA1):c.4308T>C (p.Ser1436=)	rs1060915	0.29170
NM_007294.4(BRCA1):c.3113A>G (p.Glu1038Gly)	rs16941	0.29115
NM_007294.4(BRCA1):c.2311T>C (p.Leu771=)	rs16940	0.29035
NM_007294.4(BRCA1):c.5333-491G>A	rs3092988	0.28568
NM_007294.4(BRCA1):c.442-34C>T	rs799923	0.15730
NM_007294.4(BRCA1):c.2077G>A (p.Asp693Asn)	rs4986850	0.05782
NM_007294.4(BRCA1):c.5333-153A>G	rs8176305	0.05513
NM_007294.4(BRCA1):c.1067A>G (p.Gln356Arg)	rs1799950	0.04695
NM_007294.4(BRCA1):c.5075-53C>T	rs8176258	0.01914
NM_007294.4(BRCA1):c.4956G>A (p.Met1652Ile)	rs1799967	0.01348
NM_007294.4(BRCA1):c.3119G>A (p.Ser1040Asn)	rs4986852	0.01109
NM_007294.4(BRCA1):c.2458A>G (p.Lys820Glu)	rs56082113	0.00964
NM_007294.4(BRCA1):c.1971A>G (p.Gln657=)	rs28897679	0.00707
NM_007294.4(BRCA1):c.5406+8T>C	rs55946644	0.00514
NM_007294.4(BRCA1):c.5333-221C>A	rs8176304	0.00476
NM_007294.4(BRCA1):c.5468-10C>A	rs8176316	0.00464
NM_007294.4(BRCA1):c.557C>A (p.Ser186Tyr)	rs55688530	0.00301
NM_007294.4(BRCA1):c.4987-20A>G	rs80358035	0.00252
NM_007294.4(BRCA1):c.114G>A (p.Lys38=)	rs1800062	0.00233
NM_007294.4(BRCA1):c.5333-134C>A	rs8176306	0.00200
NM_007294.4(BRCA1):c.2814A>G (p.Pro938=)	rs80356851	0.00183
NM_007294.4(BRCA1):c.21C>T (p.Arg7=)	rs149402012	0.00165
NM_007294.4(BRCA1):c.1137T>G (p.Ile379Met)	rs56128296	0.00158
NM_007294.4(BRCA1):c.2109A>G (p.Thr703=)	rs4986844	0.00147
NM_007294.4(BRCA1):c.4600G>A (p.Val1534Met)	rs55815649	0.00145
NM_007294.4(BRCA1):c.4883T>C (p.Met1628Thr)	rs4986854	0.00098
NM_007294.4(BRCA1):c.3022A>G (p.Met1008Val)	rs56321129	0.00095
NM_007294.4(BRCA1):c.5333-254A>G	rs8176303	0.00095
NM_007294.4(BRCA1):c.4840C>T (p.Pro1614Ser)	rs70953660	0.00065
NM_007294.4(BRCA1):c.4812A>G (p.Gln1604=)	rs28897693	0.00064
NM_007294.4(BRCA1):c.4992C>T (p.Leu1664=)	rs142459158	0.00061
NM_007294.4(BRCA1):c.2566T>C (p.Tyr856His)	rs80356892	0.00046
NM_007294.4(BRCA1):c.1036C>T (p.Pro346Ser)	rs80357015	0.00032
NM_007294.4(BRCA1):c.2368A>G (p.Thr790Ala)	rs41286298	0.00029
NM_007294.4(BRCA1):c.548-17G>T	rs80358014	0.00028
NM_007294.4(BRCA1):c.736T>G (p.Leu246Val)	rs28897675	0.00026
NM_007294.4(BRCA1):c.5333-304G>A	rs55633264	0.00025
NM_007294.4(BRCA1):c.4358-10C>T	rs80358111	0.00024
NM_007294.4(BRCA1):c.*106C>T	rs189442183	0.00021
NM_007294.4(BRCA1):c.571G>A (p.Val191Ile)	rs80357090	0.00021
NM_007294.4(BRCA1):c.4484+14A>G	rs80358022	0.00019
NM_007294.4(BRCA1):c.5406+33A>T	rs80358092	0.00018
NM_007294.4(BRCA1):c.1233T>G (p.Asp411Glu)	rs80357024	0.00012
NM_007294.4(BRCA1):c.1065G>A (p.Lys355=)	rs41286292	0.00011
NM_007294.4(BRCA1):c.2002C>T (p.Leu668Phe)	rs80357250	0.00011
NM_007294.4(BRCA1):c.5158A>G (p.Thr1720Ala)	rs56195342	0.00011
NM_007294.4(BRCA1):c.5152+20T>A	rs376836050	0.00009
NM_007294.4(BRCA1):c.4644G>A (p.Thr1548=)	rs28897692	0.00008
NM_007294.4(BRCA1):c.2428A>T (p.Asn810Tyr)	rs28897682	0.00006
NM_007294.4(BRCA1):c.2522G>A (p.Arg841Gln)	rs80357337	0.00006
NM_007294.4(BRCA1):c.4358-2704C>T	rs562625234	0.00006
NM_007294.4(BRCA1):c.946A>G (p.Ser316Gly)	rs55874646	0.00006
NM_007294.4(BRCA1):c.5176A>G (p.Arg1726Gly)	rs80357501	0.00005
NM_007294.4(BRCA1):c.1511G>A (p.Arg504His)	rs56272539	0.00004
NM_007294.4(BRCA1):c.1616C>T (p.Thr539Met)	rs80357374	0.00004
NM_007294.4(BRCA1):c.2669G>T (p.Gly890Val)	rs80356874	0.00004
NM_007294.4(BRCA1):c.2884G>A (p.Glu962Lys)	rs80356955	0.00004
NM_007294.4(BRCA1):c.425C>A (p.Pro142His)	rs55971303	0.00004
NM_007294.4(BRCA1):c.4729T>C (p.Ser1577Pro)	rs80356909	0.00004
NM_007294.4(BRCA1):c.81-11del	rs273902788	0.00004
NM_007294.4(BRCA1):c.2447A>G (p.His816Arg)	rs80357108	0.00003
NM_007294.4(BRCA1):c.2726A>T (p.Asn909Ile)	rs80357127	0.00003
NM_007294.4(BRCA1):c.5189A>G (p.Asn1730Ser)	rs80357171	0.00003
NM_007294.4(BRCA1):c.671-8A>G	rs80358144	0.00003
NM_007294.4(BRCA1):c.1001C>T (p.Pro334Leu)	rs41286290	0.00002
NM_007294.4(BRCA1):c.2525A>G (p.Glu842Gly)	rs28897684	0.00002
NM_007294.4(BRCA1):c.2662C>T (p.His888Tyr)	rs80357480	0.00002
NM_007294.4(BRCA1):c.3130A>G (p.Ile1044Val)	rs80357271	0.00002
NM_007294.4(BRCA1):c.4676-7C>T	rs80358005	0.00002
NM_007294.4(BRCA1):c.5153-6C>A	rs80358129	0.00002
NM_007294.4(BRCA1):c.5175A>G (p.Glu1725=)	rs191373374	0.00002
NM_007294.4(BRCA1):c.5328C>T (p.Pro1776=)	rs759867616	0.00002
NM_007294.4(BRCA1):c.5402G>A (p.Gly1801Asp)	rs531210457	0.00002
NM_007294.4(BRCA1):c.1015A>G (p.Lys339Glu)	rs55842957	0.00001
NM_007294.4(BRCA1):c.1105G>A (p.Asp369Asn)	rs56056711	0.00001
NM_007294.4(BRCA1):c.1397G>A (p.Arg466Gln)	rs199540030	0.00001
NM_007294.4(BRCA1):c.2207A>C (p.Glu736Ala)	rs397507196	0.00001
NM_007294.4(BRCA1):c.2347A>G (p.Ile783Val)	rs80356948	0.00001
NM_007294.4(BRCA1):c.2758G>A (p.Val920Ile)	rs80357361	0.00001
NM_007294.4(BRCA1):c.4342A>G (p.Ser1448Gly)	rs80357486	0.00001
NM_007294.4(BRCA1):c.4585A>G (p.Ile1529Val)	rs80357095	0.00001
NM_007294.4(BRCA1):c.463C>G (p.Gln155Glu)	rs80357180	0.00001
NM_007294.4(BRCA1):c.4985T>C (p.Phe1662Ser)	rs28897695	0.00001
NM_007294.4(BRCA1):c.5075-9A>T	rs80358059	0.00001
NM_007294.4(BRCA1):c.5456A>G (p.Asn1819Ser)	rs80357286	0.00001
NM_007294.4(BRCA1):c.716A>G (p.His239Arg)	rs80357396	0.00001
NM_007294.4(BRCA1):c.1222A>G (p.Lys408Glu)	rs80357253
NM_007294.4(BRCA1):c.2083G>A (p.Asp695Asn)	rs28897681
NM_007294.4(BRCA1):c.2612C>T (p.Pro871Leu)	rs799917
NM_007294.4(BRCA1):c.4185+11TG[5]	rs273900723
NM_007294.4(BRCA1):c.4255G>C (p.Glu1419Gln)	rs80357309
NM_007294.4(BRCA1):c.4837A>G (p.Ser1613Gly)	rs1799966
NM_007294.4(BRCA1):c.5198A>G (p.Asp1733Gly)	rs80357270
NM_007294.4(BRCA1):c.548-58del	rs8176144
NM_007294.4(BRCA1):c.81-13C>G	rs56328013
NM_007294.4(BRCA1):c.81-14C>T	rs80358006

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