List of variants in gene APOB reported as likely benign by CeGaT Center for Human Genetics Tuebingen

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 101

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HGVS	dbSNP	gnomAD frequency
NM_000384.3(APOB):c.10131G>A (p.Leu3377=)	rs1799812	0.00564
NM_000384.3(APOB):c.905-15C>G	rs72653061	0.00554
NM_000384.3(APOB):c.606A>T (p.Glu202Asp)	rs61746672	0.00387
NM_000384.3(APOB):c.6261C>A (p.Thr2087=)	rs61744855	0.00366
NM_000384.3(APOB):c.3383G>A (p.Arg1128His)	rs12713843	0.00356
NM_000384.3(APOB):c.7696G>A (p.Glu2566Lys)	rs1801696	0.00305
NM_000384.3(APOB):c.8462C>T (p.Pro2821Leu)	rs72653095	0.00267
NM_000384.3(APOB):c.13369G>A (p.Asp4457Asn)	rs183812948	0.00250
NM_000384.3(APOB):c.4825T>C (p.Leu1609=)	rs72653083	0.00242
NM_000384.3(APOB):c.11833A>G (p.Thr3945Ala)	rs1801698	0.00212
NM_000384.3(APOB):c.7615G>A (p.Val2539Ile)	rs148170480	0.00210
NM_000384.3(APOB):c.751G>A (p.Ala251Thr)	rs61741625	0.00190
NM_000384.3(APOB):c.3426G>A (p.Ser1142=)	rs142448733	0.00177
NM_000384.3(APOB):c.9105T>C (p.Asn3035=)	rs147510760	0.00166
NM_000384.3(APOB):c.9294C>T (p.Tyr3098=)	rs145777339	0.00139
NM_000384.3(APOB):c.2068-4T>A	rs41291161	0.00108
NM_000384.3(APOB):c.7612C>T (p.Leu2538=)	rs72653093	0.00108
NM_000384.3(APOB):c.12807T>C (p.Tyr4269=)	rs181340304	0.00093
NM_000384.3(APOB):c.4838G>C (p.Ser1613Thr)	rs61742247	0.00093
NM_000384.3(APOB):c.3178T>C (p.Leu1060=)	rs72653073	0.00078
NM_000384.3(APOB):c.4178C>T (p.Ala1393Val)	rs143282164	0.00073
NM_000384.3(APOB):c.2630C>T (p.Pro877Leu)	rs12714097	0.00063
NM_000384.3(APOB):c.9855C>T (p.Ile3285=)	rs72654403	0.00041
NM_000384.3(APOB):c.3382C>T (p.Arg1128Cys)	rs72653076	0.00039
NM_000384.3(APOB):c.6136G>A (p.Val2046Ile)	rs72653084	0.00035
NM_000384.3(APOB):c.2853G>A (p.Glu951=)	rs151193347	0.00031
NM_000384.3(APOB):c.9883T>C (p.Tyr3295His)	rs186299244	0.00027
NM_000384.3(APOB):c.8912A>C (p.Asn2971Thr)	rs72653098	0.00026
NM_000384.3(APOB):c.8550T>G (p.Ile2850Met)	rs148498577	0.00024
NM_000384.3(APOB):c.7863A>C (p.Leu2621=)	rs138497378	0.00022
NM_000384.3(APOB):c.13020T>C (p.Tyr4340=)	rs141339310	0.00021
NM_000384.3(APOB):c.2988C>T (p.Thr996=)	rs137875230	0.00021
NM_000384.3(APOB):c.11354C>T (p.Thr3785Ile)	rs143710616	0.00019
NM_000384.3(APOB):c.11442C>T (p.Thr3814=)	rs72654408	0.00016
NM_000384.3(APOB):c.244C>T (p.Leu82=)	rs201658954	0.00014
NM_000384.3(APOB):c.13302C>T (p.Ser4434=)	rs144040999	0.00013
NM_000384.3(APOB):c.2313G>A (p.Pro771=)	rs552986140	0.00009
NM_000384.3(APOB):c.7998A>G (p.Val2666=)	rs1042006	0.00007
NM_000384.3(APOB):c.6255A>G (p.Arg2085=)	rs779753415	0.00006
NM_000384.3(APOB):c.8134C>T (p.Arg2712Cys)	rs372245645	0.00006
NM_000384.3(APOB):c.12381C>T (p.Asp4127=)	rs145704672	0.00005
NM_000384.3(APOB):c.13452G>A (p.Thr4484=)	rs200374122	0.00005
NM_000384.3(APOB):c.5913G>A (p.Leu1971=)	rs374251542	0.00005
NM_000384.3(APOB):c.12444C>A (p.Ala4148=)	rs757789853	0.00004
NM_000384.3(APOB):c.1992T>G (p.Asn664Lys)	rs777320899	0.00004
NM_000384.3(APOB):c.4257A>G (p.Thr1419=)	rs778729560	0.00004
NM_000384.3(APOB):c.573C>T (p.Thr191=)	rs202005055	0.00004
NM_000384.3(APOB):c.6201C>T (p.His2067=)	rs143222685	0.00004
NM_000384.3(APOB):c.6875T>C (p.Ile2292Thr)	rs145977507	0.00004
NM_000384.3(APOB):c.6927A>G (p.Arg2309=)	rs201066460	0.00004
NM_000384.3(APOB):c.10416C>T (p.Thr3472=)	rs558589282	0.00003
NM_000384.3(APOB):c.1518C>G (p.Leu506=)	rs145849843	0.00003
NM_000384.3(APOB):c.2170G>T (p.Gly724Cys)	rs143425834	0.00003
NM_000384.3(APOB):c.3774G>C (p.Leu1258=)	rs752823240	0.00003
NM_000384.3(APOB):c.4299G>A (p.Ser1433=)	rs376103623	0.00003
NM_000384.3(APOB):c.11361C>T (p.Pro3787=)	rs200979977	0.00002
NM_000384.3(APOB):c.435G>A (p.Pro145=)	rs576323709	0.00002
NM_000384.3(APOB):c.8052G>A (p.Leu2684=)	rs778351930	0.00002
NM_000384.3(APOB):c.8367C>T (p.Ile2789=)	rs149734450	0.00002
NM_000384.3(APOB):c.10864C>T (p.Leu3622=)	rs769396175	0.00001
NM_000384.3(APOB):c.12343G>T (p.Val4115Phe)	rs765681925	0.00001
NM_000384.3(APOB):c.12510C>T (p.Asn4170=)	rs764649432	0.00001
NM_000384.3(APOB):c.4258C>T (p.Leu1420=)	rs1483573722	0.00001
NM_000384.3(APOB):c.4411T>C (p.Leu1471=)	rs542169352	0.00001
NM_000384.3(APOB):c.9717C>T (p.His3239=)	rs150668826	0.00001
NM_000384.3(APOB):c.11477C>T (p.Thr3826Met)
NM_000384.3(APOB):c.11541C>T (p.Ile3847=)	rs886055577
NM_000384.3(APOB):c.1182C>T (p.Ile394=)
NM_000384.3(APOB):c.12177A>G (p.Glu4059=)
NM_000384.3(APOB):c.12382G>A (p.Val4128Met)
NM_000384.3(APOB):c.12444C>T (p.Ala4148=)	rs757789853
NM_000384.3(APOB):c.12940A>G (p.Ile4314Val)
NM_000384.3(APOB):c.13131C>A (p.Ile4377=)	rs763250972
NM_000384.3(APOB):c.1661C>T (p.Pro554Leu)
NM_000384.3(APOB):c.1794C>T (p.Ala598=)	rs543224958
NM_000384.3(APOB):c.2148C>T (p.Asn716=)	rs754169002
NM_000384.3(APOB):c.2436+102A>G
NM_000384.3(APOB):c.2478T>C (p.Phe826=)	rs377697247
NM_000384.3(APOB):c.2958C>T (p.Ser986=)
NM_000384.3(APOB):c.2981C>T (p.Pro994Leu)
NM_000384.3(APOB):c.3063G>A (p.Glu1021=)
NM_000384.3(APOB):c.3122-6G>A	rs72653071
NM_000384.3(APOB):c.3285C>T (p.Asp1095=)
NM_000384.3(APOB):c.3337G>C (p.Asp1113His)
NM_000384.3(APOB):c.3427C>T (p.Pro1143Ser)
NM_000384.3(APOB):c.4266T>C (p.Cys1422=)
NM_000384.3(APOB):c.4848T>C (p.Ser1616=)
NM_000384.3(APOB):c.5066G>A (p.Arg1689His)
NM_000384.3(APOB):c.5163C>T (p.Val1721=)	rs536182427
NM_000384.3(APOB):c.5967C>T (p.Asn1989=)
NM_000384.3(APOB):c.6099C>T (p.Pro2033=)
NM_000384.3(APOB):c.6273A>G (p.Val2091=)
NM_000384.3(APOB):c.6636TGA[1] (p.Asp2213del)	rs541497967
NM_000384.3(APOB):c.6765G>A (p.Lys2255=)	rs372343882
NM_000384.3(APOB):c.6874A>C (p.Ile2292Leu)	rs1553383634
NM_000384.3(APOB):c.6929T>C (p.Ile2310Thr)	rs561774487
NM_000384.3(APOB):c.726C>T (p.Ser242=)
NM_000384.3(APOB):c.7285T>A (p.Ser2429Thr)
NM_000384.3(APOB):c.7619G>T (p.Gly2540Val)	rs571626569
NM_000384.3(APOB):c.9140C>G (p.Thr3047Arg)	rs61742323
NM_000384.3(APOB):c.9924T>C (p.His3308=)	rs370661042

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