List of variants in gene FLNC reported as benign by Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 43

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HGVS	dbSNP	gnomAD frequency
NM_001458.5(FLNC):c.5398+16T>C	rs13227216	0.32203
NM_001458.5(FLNC):c.3973C>T (p.Leu1325=)	rs34373805	0.28610
NM_001458.5(FLNC):c.3297A>G (p.Val1099=)	rs3734973	0.28603
NM_001458.5(FLNC):c.5763T>C (p.Thr1921=)	rs3816884	0.18399
NM_001458.5(FLNC):c.2265+12C>G	rs2291566	0.17192
NM_001458.5(FLNC):c.7221C>T (p.Asp2407=)	rs3816885	0.15729
NM_001458.5(FLNC):c.4431G>A (p.Leu1477=)	rs2291568	0.15512
NM_001458.5(FLNC):c.1032C>T (p.Val344=)	rs2291562	0.12206
NM_001458.5(FLNC):c.1458C>A (p.Pro486=)	rs2291563	0.11830
NM_001458.5(FLNC):c.720T>C (p.Ile240=)	rs2291560	0.11080
NM_001458.5(FLNC):c.795T>C (p.Gly265=)	rs2291561	0.10971
NM_001458.5(FLNC):c.147C>T (p.His49=)	rs3734972	0.09267
NM_001458.5(FLNC):c.4056C>T (p.Arg1352=)	rs75770585	0.08775
NM_001458.5(FLNC):c.850+18G>A	rs55907818	0.08058
NM_001458.5(FLNC):c.4700G>A (p.Arg1567Gln)	rs2291569	0.06258
NM_001458.5(FLNC):c.*1A>G	rs114713626	0.05145
NM_001458.5(FLNC):c.3838C>T (p.Leu1280=)	rs34180031	0.03419
NM_001458.5(FLNC):c.1614C>T (p.Tyr538=)	rs76046880	0.02993
NM_001458.5(FLNC):c.5669-12C>T	rs79790270	0.02786
NM_001458.5(FLNC):c.8121T>C (p.Ile2707=)	rs28437296	0.01520
NM_001458.5(FLNC):c.1374C>T (p.Pro458=)	rs115140972	0.01514
NM_001458.5(FLNC):c.8118C>T (p.Leu2706=)	rs28379666	0.01465
NM_001458.5(FLNC):c.6004+19G>A	rs12530507	0.01231
NM_001458.5(FLNC):c.2390-14C>T	rs71581921	0.00843
NM_001458.5(FLNC):c.6771A>G (p.Pro2257=)	rs34422412	0.00842
NM_001458.5(FLNC):c.5578C>T (p.Arg1860Cys)	rs181067717	0.00536
NM_001458.5(FLNC):c.1902G>A (p.Glu634=)	rs12536635	0.00414
NM_001458.5(FLNC):c.1549+15C>A	rs181134489	0.00403
NM_001458.5(FLNC):c.1425C>T (p.Asn475=)	rs143610360	0.00297
NM_001458.5(FLNC):c.1577G>A (p.Arg526Gln)	rs34932223	0.00138
NM_001458.5(FLNC):c.2501C>T (p.Thr834Met)	rs75133741	0.00136
NM_001458.5(FLNC):c.6459C>T (p.Thr2153=)	rs113618587	0.00135
NM_001458.5(FLNC):c.6005-9T>C	rs118124743	0.00133
NM_001458.5(FLNC):c.4947C>T (p.Gly1649=)	rs201069454	0.00119
NM_001458.5(FLNC):c.6309C>T (p.Thr2103=)	rs376992044	0.00116
NM_001458.5(FLNC):c.3000T>C (p.Asp1000=)	rs184454068	0.00110
NM_001458.5(FLNC):c.5766G>A (p.Ala1922=)	rs58914363	0.00108
NM_001458.5(FLNC):c.7947C>T (p.Phe2649=)	rs368849358	0.00083
NM_001458.5(FLNC):c.3966C>T (p.Gly1322=)	rs200237564	0.00045
NM_001458.5(FLNC):c.602-11C>T	rs371111092	0.00010
NM_001458.5(FLNC):c.4737+9_4737+10del	rs794727437
NM_001458.5(FLNC):c.5042C>G (p.Thr1681Arg)	rs193159707
NM_001458.5(FLNC):c.7609G>A (p.Ala2537Thr)	rs201486752

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