List of variants in gene RYR2 reported as likely benign by Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 23

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HGVS	dbSNP	gnomAD frequency
NM_001035.3(RYR2):c.13564-41A>G	rs114289907	0.03849
NM_001035.3(RYR2):c.12159G>A (p.Glu4053=)	rs41267517	0.00116
NM_001035.3(RYR2):c.8162T>C (p.Ile2721Thr)	rs201500134	0.00069
NM_001035.3(RYR2):c.1110A>G (p.Leu370=)	rs150705689	0.00063
NM_001035.3(RYR2):c.1548T>C (p.Asp516=)	rs146129084	0.00053
NM_001035.3(RYR2):c.5619A>G (p.Ala1873=)	rs373282364	0.00046
NM_001035.3(RYR2):c.577-14G>A	rs148019277	0.00021
NM_001035.3(RYR2):c.1006-12C>T	rs367998175	0.00019
NM_001035.3(RYR2):c.3024G>A (p.Ala1008=)	rs566157997	0.00019
NM_001035.3(RYR2):c.10221G>A (p.Ser3407=)	rs373769240	0.00011
NM_001035.3(RYR2):c.2772G>A (p.Leu924=)	rs780664060	0.00006
NM_001035.3(RYR2):c.9672C>T (p.Ser3224=)	rs370740528	0.00006
NM_001035.3(RYR2):c.12207T>C (p.Cys4069=)	rs756280887	0.00004
NM_001035.3(RYR2):c.13593G>A (p.Lys4531=)	rs548313130	0.00003
NM_001035.3(RYR2):c.14152-15G>A	rs371785571	0.00003
NM_001035.3(RYR2):c.11477-20T>A	rs1347306061	0.00001
NM_001035.3(RYR2):c.2922T>C (p.Ser974=)	rs750392459	0.00001
NM_001035.3(RYR2):c.4359T>C (p.Tyr1453=)	rs1054102228	0.00001
NM_001035.3(RYR2):c.6138A>G (p.Lys2046=)	rs1388384997	0.00001
NM_001035.3(RYR2):c.1108C>T (p.Leu370=)	rs534621173
NM_001035.3(RYR2):c.1395C>A (p.Pro465=)	rs111990043
NM_001035.3(RYR2):c.310-23_310-21del	rs547213887
NM_001035.3(RYR2):c.464-8A>T	rs10925391

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