ClinVar Miner

Variants from Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA), c/o University of Cambridge

Location: United Kingdom — Primary collection method: clinical testing
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
3326 0 0 0 0 3326

Gene and significance breakdown #

Total genes and gene combinations: 9
Download table as spreadsheet
Gene or gene combination pathogenic total
BRCA2 1699 1699
BRCA1 1604 1604
BRCA1, LOC110485084, LOC111589215, LOC111589216 16 16
BRCA1, LOC110485084, LOC111589215, LOC111589216, RND2 2 2
BRCA1, LOC110485084, LOC111589216 1 1
BRCA1, LOC111589215 1 1
BRCA1, LOC111589215, NBR2 1 1
BRCA2, LOC106721785, LOC112163653 1 1
BRCA2, LOC112163653 1 1

Condition and significance breakdown #

Total conditions: 2
Download table as spreadsheet
Condition pathogenic total
Breast-ovarian cancer, familial 2 1701 1701
Breast-ovarian cancer, familial 1 1625 1625

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.