ClinVar Miner

Variants from Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA), c/o University of Cambridge

Location: United Kingdom — Primary collection method: clinical testing
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
3312 0 0 0 0 3312

Gene and significance breakdown #

Total genes and gene combinations: 9
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Gene or gene combination pathogenic total
BRCA2 1697 1697
BRCA1 1594 1594
BRCA1, LOC110485084, LOC111589215, LOC111589216 16 16
BRCA1, LOC110485084, LOC111589215, LOC111589216, RND2 2 2
BRCA1, LOC110485084, LOC111589216 1 1
BRCA1, LOC111589215 1 1
BRCA1, LOC111589215, NBR2 1 1
BRCA2, LOC106721785, LOC112163653 1 1
BRCA2, LOC112163653 1 1

Condition and significance breakdown #

Total conditions: 2
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Condition pathogenic total
Breast-ovarian cancer, familial 2 1699 1699
Breast-ovarian cancer, familial 1 1614 1614

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