ClinVar Miner

Variants from Oxford Haemato-Oncology Service,Oxford University Hospitals NHS Foundation Trust

Location: United Kingdom — Primary collection method: clinical testing
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign drug response total
0 2 0 0 0 30 32

Gene and significance breakdown #

Total genes and gene combinations: 27
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Gene or gene combination likely pathogenic drug response total
TP53 0 4 4
AARS1, ABCC11, ABCC12, ACD, ACSF3, ADAD2, ADAMTS18, ADAT1, ADCY7, ADGRG1, ADGRG3, ADGRG5, AGRP, AKTIP, AMFR, ANKRD11, AP1G1, APRT, ARL2BP, ATMIN, ATP2C2, ATP6V0D1, ATXN1L, B3GNT9, BANP, BBS2, BCAR1, BCO1, BEAN1, BRD7, C16orf46, C16orf47, C16orf70, C16orf74, C16orf78, C16orf86, C16orf87, C16orf95, C16orf97, CA5A, CA7, CALB2, CAPNS2, CARMIL2, CBFA2T3, CBFB, CBLN1, CCDC102A, CCDC113, CCL17, CCL22, CDH1, CDH11, CDH13, CDH15, CDH16, CDH3, CDH5, CDH8, CDK10, CDT1, CDYL2, CENPBD1, CENPN, CENPT, CES1, CES2, CES3, CES4A, CES5A, CETP, CFAP20, CFDP1, CHD9, CHMP1A, CHST4, CHST5, CHST6, CHTF8, CIAO2B, CIAPIN1, CKLF, CKLF-CMTM1, CLEC18A, CLEC18B, CLEC18C, CLEC3A, CMC2, CMIP, CMTM1, CMTM2, CMTM3, CMTM4, CMTR2, CNEP1R1, CNGB1, CNOT1, CNTNAP4, COG4, COG8, COQ9, COTL1, COX4I1, CPNE2, CPNE7, CRISPLD2, CSNK2A2, CTCF, CTRB1, CTRB2, CTRL, CTU2, CX3CL1, CYB5B, CYBA, CYLD, DBNDD1, DDX19A, DDX19B, DDX28, DEF8, DHODH, DHX38, DNAAF1, DNAJA2, DOK4, DPEP1, DPEP2, DPEP3, DRC7, DUS2, DYNC1LI2, DYNLRB2, E2F4, EDC4, ELMO3, EMC8, ENKD1, ESRP2, EXOC3L1, EXOSC6, FA2H, FAM192A, FAM92B, FANCA, FBXL8, FBXO31, FCSK, FENDRR, FHOD1, FOXC2, FOXF1, FOXL1, FTO, GABARAPL2, GALNS, GAN, GAS8, GCSH, GFOD2, GINS2, GINS3, GLG1, GNAO1, GOT2, GPT2, GSE1, HAS3, HEATR3, HERPUD1, HP, HPR, HSBP1, HSD11B2, HSD17B2, HSDL1, HSF4, HYDIN, IL17C, IL34, IRF8, IRX3, IRX5, IRX6, IST1, ITFG1, JPH3, KARS1, KATNB1, KCNG4, KCTD19, KIAA0513, KIAA0895L, KIFC3, KLHDC4, KLHL36, LCAT, LDHD, LINC01082, LOC101927817, LOC101928417, LOC101928737, LOC400541, LOC654780, LONP2, LPCAT2, LRRC29, LRRC36, MAF, MAP1LC3B, MARVELD3, MBTPS1, MC1R, MEAK7, MIR138-2, MIR140, MIR328, MLKL, MLYCD, MMP15, MMP2, MON1B, MPHOSPH6, MT1A, MT1B, MT1E, MT1F, MT1G, MT1H, MT1M, MT1X, MT2A, MT3, MT4, MTHFSD, MTSS2, MVD, MYLK3, N4BP1, NAE1, NDRG4, NECAB2, NETO2, NFAT5, NFATC3, NIP7, NKD1, NLRC5, NOB1, NOD2, NOL3, NPIPB15, NQO1, NRN1L, NUDT21, NUDT7, NUP93, NUTF2, OGFOD1, ORC6, OSGIN1, PABPN1L, PARD6A, PDF, PDP2, PDPR, PHKB, PHLPP2, PIEZO1, PKD1L2, PKD1L3, PLA2G15, PLCG2, PLEKHG4, PLLP, PMFBP1, POLR2C, PRDM7, PRMT7, PRSS54, PSKH1, PSMB10, PSMD7, RANBP10, RBL2, RFWD3, RIPOR1, RNF166, RPGRIP1L, RPL13, RRAD, RSPRY1, SALL1, SDR42E1, SETD6, SF3B3, SHCBP1, SIAH1, SLC12A3, SLC12A4, SLC22A31, SLC38A7, SLC38A8, SLC6A2, SLC7A5, SLC7A6, SLC7A6OS, SLC9A5, SMPD3, SNAI3, SNTB2, SNX20, SPATA2L, SPATA33, SPG7, SPIRE2, ST3GAL2, SYCE1L, TAF1C, TANGO6, TAT, TCF25, TENT4B, TEPP, TERB1, TERF2, TERF2IP, THAP11, TK2, TMED6, TMEM170A, TMEM208, TMEM231, TOX3, TPPP3, TRADD, TRAPPC2L, TSNAXIP1, TUBB3, TXNL4B, USB1, USP10, UTP4, VAC14, VAT1L, VPS35, VPS4A, VPS9D1, WDR59, WFDC1, WWOX, WWP2, ZC3H18, ZCCHC14, ZDHHC1, ZDHHC7, ZFHX3, ZFP1, ZFP90, ZFPM1, ZNF19, ZNF23, ZNF276, ZNF319, ZNF423, ZNF469, ZNF778, ZNF821, ZNRF1 0 2 2
POLE 0 2 2
​intergenic 0 1 1
A1CF, ABCC2, ABLIM1, ABRAXAS2, ACADSB, ACSL5, ACSM6, ACTA2, ACTR1A, ADAM12, ADAM8, ADAMTS14, ADD3, ADGRA1, ADIRF, ADK, ADO, ADRA2A, ADRB1, AFAP1L2, AGAP10, AGAP11, AGAP4, AGAP5, AGAP6, AGAP9, AIFM2, ALDH18A1, ALOX5, ANAPC16, ANK3, ANKRD1, ANKRD2, ANKRD22, ANXA11, ANXA7, ANXA8, ANXA8L1, AP3M1, ARHGAP19, ARHGAP22, ARID5B, ARL3, ARMH3, ARMS2, AS3MT, ASAH2, ASAH2B, ASCC1, ATAD1, ATE1, ATOH7, ATP5MD, ATRNL1, AVPI1, BAG3, BBIP1, BCCIP, BICC1, BLNK, BLOC1S2, BMPR1A, BMS1, BNIP3, BORCS7, BTAF1, BTBD16, BTRC, BUB3, C10orf105, C10orf12, C10orf120, C10orf131, C10orf25, C10orf53, C10orf55, C10orf62, C10orf71, C10orf82, C10orf88, C10orf90, C10orf91, C10orf95, C10orf99, CABCOCO1, CACUL1, CALHM1, CALHM2, CALHM3, CALY, CAMK2G, CASC2, CASP7, CC2D2B, CCAR1, CCDC172, CCDC186, CCDC6, CCNJ, CCSER2, CDH23, CDHR1, CDK1, CEP55, CFAP43, CFAP46, CFAP58, CFAP70, CH25H, CHAT, CHCHD1, CHST15, CHST3, CHUK, CISD1, CLRN3, CNNM1, CNNM2, COL13A1, COL17A1, COMTD1, COX15, CPEB3, CPN1, CPXM2, CRTAC1, CSGALNACT2, CSTF2T, CTBP2, CTNNA3, CUEDC2, CUTC, CUZD1, CWF19L1, CXCL12, CYP17A1, CYP26A1, CYP26C1, CYP2C18, CYP2C19, CYP2C8, CYP2C9, CYP2E1, DCLRE1A, DDIT4, DDX21, DDX50, DENND10, DEPP1, DHX32, DKK1, DLG5, DMBT1, DNA2, DNAJB12, DNAJC12, DNAJC9, DNMBP, DNTT, DOCK1, DPCD, DPYSL4, DRGX, DUPD1, DUSP13, DUSP5, DYDC1, DYDC2, EBF3, ECD, ECHS1, EDRF1, EEF1AKMT2, EGR2, EIF3A, EIF4EBP2, EIF5AL1, ELOVL3, EMX2, EMX2OS, ENO4, ENTPD1, ENTPD7, ERCC6, ERLIN1, EXOC6, EXOSC1, FAM13C, FAM149B1, FAM160B1, FAM170B, FAM204A, FAM241B, FAM24A, FAM24B, FAM25A, FAM25C, FAM25E, FAM25G, FAM53B, FANK1, FAS, FBXL15, FBXW4, FFAR4, FGF8, FGFBP3, FGFR2, FOXI2, FRA10AC1, FRAT1, FRAT2, FRG2B, FRMPD2, FUOM, FUT11, FXYD4, GBF1, GDF10, GDF2, GFRA1, GHITM, GLRX3, GLUD1, GOLGA7B, GOT1, GPAM, GPR26, GPRIN2, GRID1, GRK5, GSTO1, GSTO2, HABP2, HECTD2, HELLS, HERC4, HHEX, HIF1AN, HK1, HKDC1, HMX2, HMX3, HNRNPF, HNRNPH3, HOGA1, HPS1, HPS6, HPSE2, HSPA12A, HTR7, HTRA1, IDE, IFIT1, IFIT1B, IFIT2, IFIT3, IFIT5, IKZF5, INA, INPP5A, INPP5F, INSYN2A, IPMK, ITPRIP, JAKMIP3, JMJD1C, KAT6B, KAZALD1, KCNIP2, KCNK18, KCNMA1, KIF11, KIF20B, KIFBP, KLLN, KNDC1, LBX1, LCOR, LDB1, LDB3, LGI1, LHPP, LINC01166, LINC01520, LIPA, LIPF, LIPJ, LIPK, LIPM, LIPN, LOC100131132, LOC101929662, LOXL4, LRIT1, LRIT2, LRMDA, LRRC18, LRRC20, LRRC27, LRRTM3, LZTS2, MACROH2A2, MAPK8, MARCHF5, MARCHF8, MARVELD1, MAT1A, MBL2, MCMBP, MCU, MFSD13A, MGMT, MICU1, MINPP1, MIR107, MIR146B, MIR346, MKI67, MMP21, MMRN2, MMS19, MORN4, MRPL43, MRPS16, MSMB, MSS51, MTG1, MTRNR2L5, MXI1, MYOF, MYOZ1, MYPN, NANOS1, NCOA4, NDST2, NDUFB8, NEURL1, NEUROG3, NFKB2, NHLRC2, NKX1-2, NKX2-3, NKX6-2, NOC3L, NODAL, NOLC1, NPFFR1, NPM3, NPS, NPY4R, NRAP, NRBF2, NRG3, NSMCE4A, NT5C2, NUDT13, NUTM2A, NUTM2B, OAT, OGA, OGDHL, OIT3, OPALIN, OPN4, OR13A1, P4HA1, PALD1, PANK1, PAOX, PAPSS2, PARG, PAX2, PBLD, PCBD1, PCDH15, PCGF5, PCGF6, PDCD11, PDCD4, PDE6C, PDLIM1, PDZD7, PDZD8, PGAM1, PGBD3, PHYHIPL, PI4K2A, PIK3AP1, PITX3, PKD2L1, PLA2G12B, PLAC9, PLAU, PLCE1, PLEKHA1, PLEKHS1, PLPP4, PNLIP, PNLIPRP1, PNLIPRP2, PNLIPRP3, POLL, POLR3A, PPA1, PPIF, PPP1R3C, PPP2R2D, PPP3CB, PPRC1, PRAP1, PRDX3, PRF1, PRKG1, PRLHR, PRXL2A, PSAP, PSD, PSTK, PTEN, PTPN20, PTPRE, PWWP2B, PYROXD2, R3HCC1L, RAB11FIP2, RASGEF1A, RASSF4, RBM20, RBP3, RBP4, REEP3, RET, RGR, RGS10, RHOBTB1, RNLS, RPP30, RPS24, RRP12, RTKN2, RUFY2, SAMD8, SAR1A, SCD, SEC23IP, SEC24C, SEC31B, SEMA4G, SFR1, SFRP5, SFTPA1, SFTPA2, SFTPD, SFXN2, SFXN3, SFXN4, SGMS1, SGPL1, SH2D4B, SH3PXD2A, SHLD2, SHOC2, SHTN1, SIRT1, SLC16A12, SLC16A9, SLC18A2, SLC18A3, SLC25A16, SLC25A28, SLC29A3, SLC35G1, SLF2, SLIT1, SLK, SMC3, SMNDC1, SNCG, SNORA12, SORBS1, SORCS1, SORCS3, SPOCK2, SPRN, SRGN, STAMBPL1, STK32C, STN1, STOX1, SUFU, SUPV3L1, SYCE1, SYNPO2L, SYT15, TACC2, TACR2, TAF5, TBATA, TBC1D12, TCERG1L, TCF7L2, TCTN3, TDRD1, TECTB, TET1, TEX36, TFAM, TIAL1, TIMM23, TLL2, TLX1, TLX1NB, TM9SF3, TMEM254, TMEM26, TMEM273, TMEM72, TNKS2, TRIM8, TRUB1, TSPAN14, TSPAN15, TUBGCP2, TWNK, TYSND1, UBE2D1, UBTD1, UNC5B, UROS, USP54, UTF1, VAX1, VCL, VDAC2, VENTX, VPS26A, VSIR, VSTM4, VTI1A, VWA2, WAPL, WASHC2A, WASHC2C, WBP1L, WDFY4, WDR11, WNT8B, XPNPEP1, ZCCHC24, ZDHHC16, ZDHHC6, ZFAND4, ZFYVE27, ZMIZ1, ZNF22, ZNF239, ZNF32, ZNF33B, ZNF365, ZNF485, ZNF488, ZNF503, ZNF511, ZNF518A, ZRANB1, ZSWIM8, ZWINT 0 1 1
ABCA2, ABO, ADAMTS13, ADAMTSL2, AGPAT2, AJM1, AK8, ANAPC2, ARRDC1, BARHL1, BRD3, C8G, C9orf116, C9orf139, C9orf163, C9orf62, CACFD1, CACNA1B, CAMSAP1, CARD9, CCDC183, CEL, CFAP77, CLIC3, COL5A1, CYSRT1, DBH, DDX31, DIPK1B, DNLZ, DPH7, DPP7, EDF1, EGFL7, EHMT1, ENTPD2, ENTPD8, ENTR1, EXD3, FAM157B, FAM163B, FAM166A, FBXW5, FCN1, FCN2, FUT7, GBGT1, GFI1B, GLT6D1, GPSM1, GRIN1, GTF3C4, GTF3C5, INPP5E, KCNT1, LCN1, LCN10, LCN12, LCN15, LCN6, LCN8, LCN9, LCNL1, LHX3, LOC651337, LRRC26, MAMDC4, MAN1B1, MED22, MIR126, MRPL41, MRPS2, MYMK, NACC2, NDOR1, NELFB, NOTCH1, NOXA1, NPDC1, NRARP, NSMF, OBP2A, OBP2B, OLFM1, PAEP, PAXX, PHPT1, PMPCA, PNPLA7, PPP1R26, PTGDS, QSOX2, RABL6, RALGDS, REXO4, RNF208, RNF224, RNU6ATAC, RPL7A, RXRA, SAPCD2, SARDH, SEC16A, SLC2A6, SLC34A3, SNAPC4, SNHG7, SOHLH1, SPACA9, SSNA1, STKLD1, STPG3, SURF1, SURF2, SURF4, SURF6, TMEM141, TMEM203, TMEM210, TMEM250, TOR4A, TPRN, TRAF2, TSC1, TUBB4B, UAP1L1, UBAC1, VAV2, WDR5, ZMYND19 0 1 1
ABCC2, ACSM6, ACTA2, ACTR1A, ADIRF, AGAP11, ALDH18A1, ANKRD1, ANKRD2, ANKRD22, ARHGAP19, ARL3, ARMH3, AS3MT, ATAD1, ATP5MD, AVPI1, BLNK, BLOC1S2, BMPR1A, BORCS7, BTAF1, BTRC, C10orf12, C10orf131, C10orf62, C10orf95, C10orf99, CALHM1, CALHM2, CALHM3, CC2D2B, CCNJ, CCSER2, CDHR1, CEP55, CH25H, CHUK, CNNM1, CNNM2, COL17A1, COX15, CPEB3, CPN1, CRTAC1, CUEDC2, CUTC, CWF19L1, CYP17A1, CYP26A1, CYP26C1, CYP2C18, CYP2C19, CYP2C8, CYP2C9, DNMBP, DNTT, DPCD, ELOVL3, ENTPD1, ENTPD7, ERLIN1, EXOC6, EXOSC1, FAM25A, FAS, FBXL15, FBXW4, FFAR4, FGF8, FGFBP3, FRA10AC1, FRAT1, FRAT2, GBF1, GHITM, GLUD1, GOLGA7B, GOT1, GRID1, HECTD2, HELLS, HHEX, HIF1AN, HOGA1, HPS1, HPS6, HPSE2, HTR7, IDE, IFIT1, IFIT1B, IFIT2, IFIT3, IFIT5, INA, KAZALD1, KCNIP2, KIF11, KIF20B, KLLN, LBX1, LCOR, LDB1, LDB3, LGI1, LINC01520, LIPA, LIPF, LIPJ, LIPK, LIPM, LIPN, LOC101929662, LOXL4, LRIT1, LRIT2, LZTS2, MARCHF5, MARVELD1, MFSD13A, MINPP1, MIR107, MIR146B, MIR346, MMRN2, MMS19, MORN4, MRPL43, MYOF, NDUFB8, NEURL1, NFKB2, NKX2-3, NOC3L, NOLC1, NPM3, NT5C2, NUTM2A, OGA, OPALIN, OPN4, PANK1, PAPSS2, PAX2, PCGF5, PCGF6, PDCD11, PDE6C, PDLIM1, PDZD7, PGAM1, PI4K2A, PIK3AP1, PITX3, PKD2L1, PLCE1, POLL, PPP1R3C, PPRC1, PSD, PTEN, PYROXD2, R3HCC1L, RBP4, RGR, RNLS, RPP30, RRP12, SCD, SEC31B, SEMA4G, SFRP5, SFXN2, SFXN3, SH3PXD2A, SHLD2, SLC16A12, SLC25A28, SLC35G1, SLF2, SLIT1, SLK, SNCG, SNORA12, SORBS1, STAMBPL1, STN1, SUFU, TAF5, TBC1D12, TCTN3, TLL2, TLX1, TLX1NB, TM9SF3, TNKS2, TRIM8, TWNK, UBTD1, WAPL, WBP1L, WNT8B, ZDHHC16, ZFYVE27, ZNF518A 0 1 1
ABHD15, ADAP2, ALDOC, ANKRD13B, ATAD5, BLMH, COPRS, CORO6, CPD, CRLF3, CRYBA1, DHRS13, EFCAB5, ERAL1, EVI2A, EVI2B, FAM222B, FLOT2, FOXN1, GIT1, GOSR1, IFT20, KIAA0100, KSR1, LGALS9, LRRC37B, LYRM9, MIR144, MIR193A, MIR451A, MYO18A, NEK8, NF1, NLK, NOS2, NSRP1, NUFIP2, OMG, PHF12, PIGS, PIPOX, POLDIP2, PROCA1, RAB11FIP4, RAB34, RHBDL3, RHOT1, RNF135, RPL23A, SARM1, SDF2, SEBOX, SEZ6, SLC13A2, SLC46A1, SLC6A4, SPAG5, SSH2, SUPT6H, SUZ12, TAOK1, TBC1D29P, TEFM, TIAF1, TLCD1, TMEM199, TMEM97, TMIGD1, TNFAIP1, TP53I13, TRAF4, UNC119, UTP6, VTN, WSB1 0 1 1
ACADVL, ACAP1, ALOX12B, ALOX15B, ALOXE3, ARHGEF15, ASGR1, ASGR2, ATP1B2, AURKB, BORCS6, CD68, CHD3, CHRNB1, CLDN7, CLEC10A, CNTROB, CTC1, CTDNEP1, CYB5D1, DLG4, DNAH2, DVL2, EFNB3, EIF4A1, EIF5A, ELP5, FGF11, FXR2, GABARAP, GPS2, GUCY2D, HES7, KCNAB3, KCTD11, KDM6B, MPDU1, NAA38, NEURL4, NLGN2, PER1, PFAS, PHF23, PLSCR3, POLR2A, RANGRF, SAT2, SENP3, SHBG, SLC16A11, SLC16A13, SLC25A35, SLC2A4, SLC35G6, SOX15, SPEM1, SPEM2, TMEM102, TMEM107, TMEM256, TMEM88, TMEM95, TNFSF12, TNFSF12-TNFSF13, TNFSF13, TNK1, TP53, TRAPPC1, TRG-GCC2-6, TRK-TTT3-5, TRL-TAG1-1, TRQ-CTG1-5, TRR-TCT2-1, VAMP2, WRAP53, YBX2, ZBTB4 0 1 1
ACER2, ADAMTSL1, BNC2, CCDC171, CDKN2A, CDKN2B, CER1, CNTLN, DENND4C, DMRTA1, ELAVL2, FOCAD, FREM1, HACD4, HAUS6, IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNB1, IFNE, IFNW1, IZUMO3, KLHL9, LURAP1L, MIR31, MLLT3, MPDZ, MTAP, NFIB, PLIN2, PSIP1, PTPRD, RPS6, RRAGA, SAXO1, SH3GL2, SLC24A2, SNAPC3, TTC39B, TUSC1, TYRP1, ZDHHC21 0 1 1
ACMSD, ACOXL, ACTR3, ACVR1, ACVR1C, ACVR2A, AMER3, AMMECR1L, ANAPC1, ARHGAP15, ARHGEF4, ARL5A, ARL6IP6, BAZ2B, BCL2L11, BIN1, BUB1, C1QL2, C2orf27A, C2orf27B, C2orf49, C2orf76, CACNB4, CBWD2, CCDC115, CCDC138, CCDC148, CCDC74A, CCDC74B, CCDC93, CCNT2, CD302, CFC1, CFC1B, CHCHD5, CKAP2L, CLASP1, CNTNAP5, COBLL1, CSRNP3, CXCR4, CYP27C1, CYTIP, DAPL1, DARS1, DBI, DDX18, DPP10, DPP4, ECRG4, EDAR, EN1, EPB41L5, EPC2, ERCC3, ERMN, FAM168B, FAP, FBLN7, FHL2, FIGN, FMNL2, FOXD4L1, GALNT13, GALNT3, GALNT5, GCA, GCC2, GCG, GLI2, GPD2, GPR148, GPR17, GPR39, GPR45, GRB14, GTDC1, GYPC, HNMT, HS6ST1, IFIH1, IL1A, IL1B, IL1F10, IL1RN, IL36A, IL36B, IL36G, IL36RN, IL37, IMP4, INHBB, INSIG2, ITGB6, IWS1, KCNH7, KCNJ3, KYNU, LCT, LIMS1, LIMS2, LIMS3, LIMS4, LRP1B, LY75, LY75-CD302, LYPD1, LYPD6, LYPD6B, MALL, MAP3K19, MAP3K2, MARCHF7, MARCO, MBD5, MCM6, MERTK, MGAT5, MIR128-1, MMADHC, MRPS9, MYO7B, MZT2A, MZT2B, NCK2, NCKAP5, NEB, NIFK, NMI, NPHP1, NR4A2, NT5DC4, NXPH2, ORC4, PAX8, PKP4, PLA2R1, PLEKHB2, POLR1B, POLR2D, POTEE, POTEF, POTEI, POTEJ, POU3F3, PROC, PRPF40A, PSD4, PSMD14, PTPN18, PTPN4, R3HDM1, RAB3GAP1, RAB6C, RABL2A, RALB, RANBP2, RBM43, RBMS1, RGPD3, RGPD4, RGPD5, RGPD6, RGPD8, RIF1, RND3, RNU4ATAC, RPRM, SAP130, SCN1A, SCN2A, SCN3A, SCN7A, SCN9A, SCTR, SEPTIN10, SFT2D3, SLC20A1, SLC35F5, SLC38A11, SLC4A10, SLC5A7, SMPD4, SOWAHC, SPOPL, ST6GAL2, STAM2, STEAP3, SULT1C2, SULT1C3, SULT1C4, TANC1, TANK, TBR1, TFCP2L1, TGFBRAP1, THSD7B, TMEM163, TMEM177, TMEM185B, TMEM37, TMEM87B, TNFAIP6, TSN, TTC21B, TTL, TUBA3D, TUBA3E, UBXN4, UGGT1, UPP2, UXS1, WDR33, WDSUB1, XIRP2, ZC3H6, ZC3H8, ZEB2, ZNF806, ZRANB3 0 1 1
AKAP7, ARG1, ARHGAP18, ASF1A, C6orf58, CALHM4, CALHM5, CALHM6, CCN2, CENPW, CEP85L, CLVS2, COL10A1, CTAGE9, DCBLD1, DSE, ECHDC1, ENPP1, ENPP3, EPB41L2, FABP7, FAM162B, FAM184A, FRK, GJA1, GOPC, GPRC6A, HDAC2, HDDC2, HEY2, HINT3, HS3ST5, HSF2, KIAA0408, KPNA5, L3MBTL3, LAMA2, MAN1A1, MARCKS, MCM9, MED23, NCOA7, NKAIN2, NT5DC1, NUS1, OR2A4, PKIB, PLN, PTPRK, RFX6, RNF146, RNF217, ROS1, RSPH4A, RSPO3, RWDD1, SAMD3, SERINC1, SLC35F1, SMLR1, SMPDL3A, SOGA3, TBC1D32, THEMIS, TMEM200A, TMEM244, TPD52L1, TRAPPC3L, TRDN, TRMT11, TSPYL1, TSPYL4, VGLL2, ZUP1 0 1 1
ALOX5AP, AMER2, ATP12A, ATP8A2, B3GLCT, BRCA2, C1QTNF9, C1QTNF9B, CDK8, CDX2, CENPJ, FLT1, FLT3, FRY, GPR12, GSX1, GTF3A, HMGB1, HSPH1, KATNAL1, KL, LINC00543, LNX2, MEDAG, MIPEP, MTIF3, MTMR6, MTUS2, N4BP2L1, N4BP2L2, NUP58, PABPC3, PAN3, PARP4, PCOTH, PDS5B, PDX1, POLR1D, POMP, RASL11A, RNF17, RNF6, RPL21, RXFP2, SHISA2, SLC46A3, SLC7A1, SPATA13, STARD13, TEX26, TNFRSF19, UBL3, URAD, USP12, USPL1, WASF3, ZAR1L 0 1 1
ARID1A 0 1 1
ATAD1, KLLN, LIPJ, PTEN, RNLS 0 1 1
ATP1B2, DNAH2, EFNB3, FXR2, SAT2, SHBG, TP53, WRAP53 0 1 1
BRCA2, FRY, KL, N4BP2L1, N4BP2L2, PDS5B, RXFP2, STARD13, ZAR1L 0 1 1
CDKN2A, CDKN2A-DT, CDKN2B, DMRTA1, LINC01239, LOC114022702 0 1 1
CDKN2A, CDKN2A-DT, CDKN2B, ERVFRD-3, LOC114022702 0 1 1
DDX3X 0 1 1
LOC100996664, LOC108281166, LOC110121358, LOC110121412, LOC110121431, LOC111365187, LOC112272551, RAD51B, ZFP36L1 0 1 1
NFE2L2 1 0 1
NRAS 0 1 1
PIK3CA 0 1 1
RAD51B 0 1 1
SETD2 0 1 1
SMAD4 1 0 1

Condition and significance breakdown #

Total conditions: 10
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Condition likely pathogenic drug response total
PARP Inhibitor response 0 18 18
VEGF Inhibitors response 0 3 3
Anti-PDL1 response 0 2 2
Colorectal cancer 2 0 2
mTOR Inhibitor response 0 2 2
AKT1 Inhibitor response 0 1 1
Histone Methylation Therapy response 0 1 1
MEK Inhibitor response 0 1 1
RAS Inhibitor response 0 1 1
WEE1 Inhibitor response 0 1 1

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