List of variants in gene SOS1 reported as likely benign by ClinGen RASopathy Variant Curation Expert Panel

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 16

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HGVS	dbSNP	gnomAD frequency
NM_005633.4(SOS1):c.698A>G (p.Asn233Ser)	rs144934321	0.00026
NM_005633.4(SOS1):c.1705C>G (p.Leu569Val)	rs200786705	0.00019
NM_005633.4(SOS1):c.109A>G (p.Thr37Ala)	rs150565592	0.00016
NM_005633.4(SOS1):c.3330G>C (p.Ser1110=)	rs146383828	0.00013
NM_005633.4(SOS1):c.3600C>G (p.Asp1200Glu)	rs141594736	0.00013
NM_005633.4(SOS1):c.1647A>G (p.Thr549=)	rs139683425	0.00011
NM_005633.4(SOS1):c.280A>G (p.Ile94Val)	rs144757941	0.00009
NM_005633.4(SOS1):c.3322G>A (p.Asp1108Asn)	rs199856844	0.00009
NM_005633.4(SOS1):c.1490G>A (p.Arg497Gln)	rs371314838	0.00004
NM_005633.4(SOS1):c.2156G>C (p.Gly719Ala)	rs200794965	0.00004
NM_005633.4(SOS1):c.899G>A (p.Arg300Gln)	rs754374236	0.00002
NM_005633.4(SOS1):c.350T>G (p.Val117Gly)	rs201085754	0.00001
NM_005633.4(SOS1):c.225A>G (p.Gln75=)	rs560037748
NM_005633.4(SOS1):c.294G>A (p.Lys98=)	rs748478952
NM_005633.4(SOS1):c.3658G>A (p.Val1220Met)	rs776814547
NM_005633.4(SOS1):c.3709C>A (p.Pro1237Thr)	rs371408734

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