List of variants in gene POLE reported as benign by Genome Diagnostics Laboratory, Amsterdam University Medical Center

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 24

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HGVS	dbSNP	gnomAD frequency
NM_006231.4(POLE):c.3379-5T>C	rs5744886	0.02649
NM_006231.4(POLE):c.3126G>A (p.Lys1042=)	rs5744856	0.02344
NM_006231.4(POLE):c.2340G>A (p.Ser780=)	rs5744822	0.02051
NM_006231.4(POLE):c.2320-13A>G	rs75329753	0.01853
NM_006231.4(POLE):c.2550C>T (p.Ile850=)	rs5744834	0.01438
NM_006231.4(POLE):c.6418G>A (p.Glu2140Lys)	rs5745066	0.01416
NM_006231.4(POLE):c.5678+4C>T	rs5744973	0.01405
NM_006231.4(POLE):c.91G>T (p.Ala31Ser)	rs34047482	0.01320
NM_006231.4(POLE):c.6330+18C>T	rs5745024	0.01301
NM_006231.4(POLE):c.2174-8G>A	rs117409343	0.01137
NM_006231.4(POLE):c.5804G>A (p.Cys1935Tyr)	rs5744991	0.00843
NM_006231.4(POLE):c.1007A>G (p.Asn336Ser)	rs5744760	0.00805
NM_006231.4(POLE):c.1470C>T (p.Asp490=)	rs5744777	0.00614
NM_006231.4(POLE):c.6494G>A (p.Arg2165His)	rs5745068	0.00550
NM_006231.4(POLE):c.6763A>T (p.Ile2255Phe)	rs73155056	0.00487
NM_006231.4(POLE):c.1359+9G>A	rs75135381	0.00461
NM_006231.4(POLE):c.4259C>T (p.Ala1420Val)	rs41561818	0.00325
NM_006231.4(POLE):c.5334C>T (p.Ala1778=)	rs11146986	0.00205
NM_006231.4(POLE):c.1323G>A (p.Pro441=)	rs116573514	0.00174
NM_006231.4(POLE):c.2083T>A (p.Phe695Ile)	rs5744799
NM_006231.4(POLE):c.2865-4del	rs369732588
NM_006231.4(POLE):c.2865-4dup	rs369732588
NM_006231.4(POLE):c.4552-10G>T	rs5744946
NM_006231.4(POLE):c.4952+17_4952+19dup	rs571641918

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