ClinVar Miner

Variants from 3DMed Clinical Laboratory Inc

Location: China — Primary collection method: clinical testing
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
57 3 87 4 0 151

Gene and significance breakdown #

Total genes and gene combinations: 14
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign total
APC 2 0 45 0 47
BRCA2 12 1 28 2 43
BRCA1 22 1 8 1 32
MLH1 6 0 0 0 6
MSH2 4 0 0 0 4
PALB2 3 0 1 0 4
CHEK2 2 0 1 0 3
EGFR 2 0 1 0 3
CDH1 0 1 1 0 2
MSH6 1 0 0 1 2
RET 2 0 0 0 2
BRIP1 0 0 1 0 1
PMS2 1 0 0 0 1
POLE 0 0 1 0 1

Condition and significance breakdown #

Total conditions: 33
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Condition pathogenic likely pathogenic uncertain significance likely benign total
Neoplasm of the breast 17 1 11 1 30
Cancer of the pancreas 5 0 13 2 20
Ovarian cancer 10 0 6 1 17
Colon cancer 6 0 7 0 13
Carcinoma of colon 5 0 7 0 12
Infiltrating duct carcinoma of breast 4 0 7 0 11
Neoplasm of the liver 0 0 10 0 10
Neoplasm of stomach 0 1 4 0 5
Adenocarcinoma of the colon 2 0 2 0 4
Rectal Adenocarcinoma 0 0 4 0 4
Colorectal cancer 0 0 3 0 3
Intrahepatic Cholangiocarcinoma 0 0 3 0 3
Lung adenocarcinoma 2 0 1 0 3
Malignant tumor of sigmoid colon 1 0 1 1 3
Duodenal adenocarcinoma 0 0 2 0 2
Gastrointestinal stromal tumor of small intestine 0 0 2 0 2
Hepatocellular carcinoma 0 0 2 0 2
Malignant tumor of ascending colon 1 0 1 0 2
Neuroendocrine tumor of pancreas 2 0 0 0 2
Ovarian Serous Surface Papillary Adenocarcinoma 1 1 0 0 2
Adenocarcinoma of stomach 0 0 1 0 1
Carcinoma of head of pancreas 0 0 1 0 1
Familial multiple polyposis syndrome 1 0 0 0 1
Gastrointestinal stroma tumor 0 0 1 0 1
Invasive Breast Carcinoma 0 0 1 0 1
Invasive Lobular Breast Carcinoma 0 0 1 0 1
Klatskin tumor 0 0 1 0 1
Malignant tumor of esophagus 0 0 1 0 1
Malignant tumor of prostate 0 0 1 0 1
Medullary thyroid carcinoma 1 0 0 0 1
Sarcoma 1 0 0 0 1
Squamous cell lung carcinoma 1 0 0 0 1
Thyroid carcinoma 1 0 0 0 1

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