ClinVar Miner

Variants from 3DMed Clinical Laboratory Inc

Location: China  Primary collection method: clinical testing
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
57 3 87 4 0 151

Gene and significance breakdown #

Total genes and gene combinations: 15
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign total
APC 2 0 45 0 47
BRCA2 12 1 28 2 43
BRCA1 16 1 6 1 24
BRCA1, LOC126862571 6 0 2 0 8
MLH1 6 0 0 0 6
MSH2 4 0 0 0 4
PALB2 3 0 1 0 4
CHEK2 2 0 1 0 3
EGFR 2 0 1 0 3
CDH1 0 1 1 0 2
MSH6 1 0 0 1 2
RET 2 0 0 0 2
BRIP1 0 0 1 0 1
PMS2 1 0 0 0 1
POLE 0 0 1 0 1

Condition and significance breakdown #

Total conditions: 33
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Condition pathogenic likely pathogenic uncertain significance likely benign total
Breast neoplasm 17 1 11 1 30
Cancer of the pancreas 5 0 13 2 20
Ovarian cancer 10 0 6 1 17
Colon cancer 6 0 7 0 13
Carcinoma of colon 5 0 7 0 12
Infiltrating duct carcinoma of breast 4 0 7 0 11
Neoplasm of the liver 0 0 10 0 10
Neoplasm of stomach 0 1 4 0 5
Colon adenocarcinoma 2 0 2 0 4
Rectum adenocarcinoma 0 0 4 0 4
Colorectal cancer 0 0 3 0 3
Intrahepatic cholangiocarcinoma 0 0 3 0 3
Lung adenocarcinoma 2 0 1 0 3
Sigmoid colon cancer 1 0 1 1 3
Duodenal adenocarcinoma 0 0 2 0 2
Gastrointestinal stromal tumor of small intestine 0 0 2 0 2
Hepatocellular carcinoma 0 0 2 0 2
Malignant tumor of ascending colon 1 0 1 0 2
Neuroendocrine tumor of pancreas 2 0 0 0 2
Ovarian serous surface papillary adenocarcinoma 1 1 0 0 2
Carcinoma of head of pancreas 0 0 1 0 1
Familial multiple polyposis syndrome 1 0 0 0 1
Gastric adenocarcinoma 0 0 1 0 1
Gastrointestinal stromal tumor 0 0 1 0 1
Invasive breast carcinoma 0 0 1 0 1
Invasive lobular breast carcinoma 0 0 1 0 1
Klatskin tumor 0 0 1 0 1
Malignant tumor of esophagus 0 0 1 0 1
Malignant tumor of prostate 0 0 1 0 1
Medullary thyroid carcinoma 1 0 0 0 1
Sarcoma 1 0 0 0 1
Squamous cell lung carcinoma 1 0 0 0 1
Thyroid gland carcinoma 1 0 0 0 1

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