List of variants in gene BRCA2 reported as uncertain significance by 3DMed Clinical Laboratory Inc

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 28

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HGVS	dbSNP	gnomAD frequency
NM_000059.4(BRCA2):c.440A>G (p.Gln147Arg)	rs80358674	0.00025
NM_000059.4(BRCA2):c.6325G>A (p.Val2109Ile)	rs79456940	0.00006
NM_000059.4(BRCA2):c.7522G>A (p.Gly2508Ser)	rs80358978	0.00004
NM_000059.4(BRCA2):c.2671G>C (p.Val891Leu)	rs756951335	0.00002
NM_000059.4(BRCA2):c.353G>A (p.Arg118His)	rs80358603	0.00002
NM_000059.4(BRCA2):c.10150C>T (p.Arg3384Ter)	rs397507568	0.00001
NM_000059.4(BRCA2):c.215A>G (p.Asn72Ser)	rs276174818	0.00001
NM_000059.4(BRCA2):c.2186T>C (p.Ile729Thr)	rs431825296	0.00001
NM_000059.4(BRCA2):c.2838T>G (p.Asp946Glu)	rs149753706	0.00001
NM_000059.4(BRCA2):c.4376A>G (p.Asn1459Ser)	rs117187202	0.00001
NM_000059.4(BRCA2):c.7488G>C (p.Lys2496Asn)	rs774994294	0.00001
NM_000059.4(BRCA2):c.8050A>G (p.Lys2684Glu)	rs1289414853	0.00001
NM_000059.4(BRCA2):c.8356G>A (p.Ala2786Thr)	rs80359077	0.00001
NM_000059.4(BRCA2):c.10131A>C (p.Glu3377Asp)	rs1064793835
NM_000059.4(BRCA2):c.1166C>A (p.Pro389Gln)	rs397507263
NM_000059.4(BRCA2):c.2482T>C (p.Tyr828His)	rs1060502466
NM_000059.4(BRCA2):c.2803G>T (p.Asp935Tyr)	rs28897716
NM_000059.4(BRCA2):c.3074A>G (p.Lys1025Arg)	rs1555283038
NM_000059.4(BRCA2):c.3875T>A (p.Leu1292Gln)	rs1555283446
NM_000059.4(BRCA2):c.4025G>A (p.Ser1342Asn)	rs1270552356
NM_000059.4(BRCA2):c.4312G>A (p.Val1438Ile)	rs786202874
NM_000059.4(BRCA2):c.4639G>A (p.Asp1547Asn)	rs1555283880
NM_000059.4(BRCA2):c.5323G>C (p.Val1775Leu)	rs1555284171
NM_000059.4(BRCA2):c.63A>G (p.Lys21=)	rs1280004443
NM_000059.4(BRCA2):c.6715G>A (p.Glu2239Lys)	rs276174876
NM_000059.4(BRCA2):c.7426G>C (p.Glu2476Gln)	rs879248686
NM_000059.4(BRCA2):c.9206G>A (p.Cys3069Tyr)	rs587782091
NM_000059.4(BRCA2):c.92G>T (p.Trp31Leu)	rs397508045

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