List of variants in gene PTEN reported as uncertain significance by Clingen PTEN Variant Curation Expert Panel, Clingen

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 46

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HGVS	dbSNP	gnomAD frequency
NM_000314.8(PTEN):c.*5T>C	rs1006891299	0.00005
NM_000314.8(PTEN):c.159A>G (p.Val53=)	rs189583426	0.00003
NM_000314.8(PTEN):c.-765G>A	rs587776674	0.00002
NM_000314.8(PTEN):c.1093G>A (p.Val365Ile)	rs758542021	0.00001
NM_000314.8(PTEN):c.114T>G (p.Pro38=)	rs748040144	0.00001
NM_000314.8(PTEN):c.1171C>T (p.Pro391Ser)	rs786203911	0.00001
NM_000314.8(PTEN):c.253+4G>A	rs1060500112	0.00001
NM_000314.8(PTEN):c.78C>T (p.Thr26=)	rs786201280	0.00001
NM_000314.8(PTEN):c.841C>G (p.Pro281Ala)	rs750705904	0.00001
NM_000314.8(PTEN):c.*10del	rs756681683
NM_000314.8(PTEN):c.1027-4C>G	rs587782788
NM_000314.8(PTEN):c.1052_1054del (p.Val351del)	rs587780003
NM_000314.8(PTEN):c.105G>A (p.Met35Ile)	rs1554893782
NM_000314.8(PTEN):c.1061C>T (p.Pro354Leu)	rs375709098
NM_000314.8(PTEN):c.10A>G (p.Ile4Val)
NM_000314.8(PTEN):c.1105G>A (p.Val369Ile)	rs587782224
NM_000314.8(PTEN):c.112C>T (p.Pro38Ser)	rs587780004
NM_000314.8(PTEN):c.1133_1136del (p.Arg378fs)	rs1064794878
NM_000314.8(PTEN):c.209+3A>T	rs786202612
NM_000314.8(PTEN):c.304A>C (p.Lys102Gln)	rs786202944
NM_000314.8(PTEN):c.304_306dup (p.Lys102dup)	rs587782641
NM_000314.8(PTEN):c.338G>T (p.Ser113Ile)	rs587781254
NM_000314.8(PTEN):c.344A>G (p.Asp115Gly)	rs869312775
NM_000314.8(PTEN):c.355G>T (p.Val119Phe)	rs139767111
NM_000314.8(PTEN):c.35A>G (p.Asn12Ser)	rs1085308044
NM_000314.8(PTEN):c.364A>G (p.Ile122Val)	rs786202740
NM_000314.8(PTEN):c.39_41del (p.Arg15del)	rs1114167625
NM_000314.8(PTEN):c.40A>G (p.Arg14Gly)	rs1085308047
NM_000314.8(PTEN):c.42G>A (p.Arg14=)	rs1064794513
NM_000314.8(PTEN):c.46T>C (p.Tyr16His)	rs1064796078
NM_000314.8(PTEN):c.493-7C>T	rs1554900492
NM_000314.8(PTEN):c.545T>C (p.Leu182Ser)	rs794729664
NM_000314.8(PTEN):c.599T>C (p.Phe200Ser)	rs786204867
NM_000314.8(PTEN):c.685T>A (p.Ser229Thr)	rs587781998
NM_000314.8(PTEN):c.698G>A (p.Arg233Gln)	rs770025422
NM_000314.8(PTEN):c.700C>T (p.Arg234Trp)	rs786201730
NM_000314.8(PTEN):c.701G>A (p.Arg234Gln)	rs121909235
NM_000314.8(PTEN):c.715A>G (p.Met239Val)	rs786201758
NM_000314.8(PTEN):c.79+20C>G	rs587781291
NM_000314.8(PTEN):c.79+7A>T	rs374331677
NM_000314.8(PTEN):c.80-5C>T	rs1060503842
NM_000314.8(PTEN):c.802-3T>A	rs587780712
NM_000314.8(PTEN):c.838A>G (p.Ile280Val)	rs1474354667
NM_000314.8(PTEN):c.914G>A (p.Ser305Asn)	rs587780007
NM_000314.8(PTEN):c.947T>C (p.Leu316Pro)	rs1064793345
NM_000314.8(PTEN):c.98T>C (p.Ile33Thr)	rs1554893771

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