List of variants in gene TP53 reported as uncertain significance by ClinGen TP53 Variant Curation Expert Panel, ClinGen

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 27

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HGVS	dbSNP	gnomAD frequency
NM_000546.6(TP53):c.883C>T (p.Pro295Ser)	rs1131691006	0.00004
NM_000546.6(TP53):c.214C>G (p.Pro72Ala)	rs587782769	0.00003
NM_000546.6(TP53):c.467G>A (p.Arg156His)	rs371524413	0.00003
NM_000546.6(TP53):c.784G>A (p.Gly262Ser)	rs200579969	0.00002
NM_000546.6(TP53):c.1000G>C (p.Gly334Arg)	rs730882028	0.00001
NM_000546.6(TP53):c.353C>T (p.Thr118Ile)	rs1064794141	0.00001
NM_000546.6(TP53):c.370T>A (p.Cys124Ser)	rs730881997	0.00001
NM_000546.6(TP53):c.37C>T (p.Pro13Ser)	rs1060501208	0.00001
NM_000546.6(TP53):c.393C>A (p.Asn131Lys)	rs769270327	0.00001
NM_000546.6(TP53):c.461G>A (p.Gly154Asp)	rs762846821	0.00001
NM_000546.6(TP53):c.523C>T (p.Arg175Cys)	rs138729528	0.00001
NM_000546.6(TP53):c.607G>A (p.Val203Met)	rs730882003	0.00001
NM_000546.6(TP53):c.800G>A (p.Arg267Gln)	rs587780075	0.00001
NM_000546.6(TP53):c.946C>A (p.Pro316Thr)	rs772773208	0.00001
NM_000546.6(TP53):c.1003C>T (p.Arg335Cys)	rs375444154
NM_000546.6(TP53):c.1009C>A (p.Arg337Ser)	rs587782529
NM_000546.6(TP53):c.206C>G (p.Ala69Gly)	rs756233241
NM_000546.6(TP53):c.214_215delinsTG (p.Pro72Cys)	rs730882014
NM_000546.6(TP53):c.431A>T (p.Gln144Leu)	rs786203071
NM_000546.6(TP53):c.436T>G (p.Trp146Gly)	rs786203064
NM_000546.6(TP53):c.46C>A (p.Gln16Lys)	rs2151047550
NM_000546.6(TP53):c.482_487del (p.Ala161_Tyr163delinsAsp)	rs2073376974
NM_000546.6(TP53):c.511G>A (p.Glu171Lys)	rs587781845
NM_000546.6(TP53):c.541C>A (p.Arg181Ser)	rs587782596
NM_000546.6(TP53):c.845G>T (p.Arg282Leu)	rs730882008
NM_000546.6(TP53):c.85AAC[1] (p.Asn30del)	rs587782270
NM_000546.6(TP53):c.97-3C>T	rs786203749

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