ClinVar Miner

List of variants in gene WFS1 reported as benign by Clinical Genomics, Uppaluri K&H Personalized Medicine Clinic

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 234
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HGVS dbSNP gnomAD frequency
NM_006005.3(WFS1):c.684C>G (p.Arg228=) rs1801213 0.68223
NM_006005.3(WFS1):c.713-783G>A rs4689395 0.63899
NM_006005.3(WFS1):c.461-208G>C rs11732208 0.63585
NM_006005.3(WFS1):c.713-1341C>G rs6838400 0.63540
NM_006005.3(WFS1):c.712+195C>G rs11725500 0.63296
NM_006005.3(WFS1):c.461-9A>G rs10010131 0.63169
NM_006005.3(WFS1):c.713-1185C>A rs6446481 0.63035
NM_006005.3(WFS1):c.713-1203C>T rs6446480 0.62693
NM_006005.3(WFS1):c.713-1075C>G rs6446482 0.62564
NM_006005.3(WFS1):c.461-15C>T rs9998519 0.62200
NM_006005.3(WFS1):c.461-281G>C rs11732178 0.59793
NM_006005.3(WFS1):c.232+90G>A rs28420833 0.59278
NM_006005.3(WFS1):c.862-164C>G rs4688991 0.58956
NM_006005.3(WFS1):c.862-185C>T rs4689398 0.58804
NM_006005.3(WFS1):c.2433G>A (p.Lys811=) rs1046314 0.57941
NM_006005.3(WFS1):c.*683C>T rs3200 0.57543
NM_006005.3(WFS1):c.713-1018A>G rs6820509 0.40867
NM_006005.3(WFS1):c.713-915C>T rs73071607 0.16041
NM_006005.3(WFS1):c.713-993C>T rs28729642 0.11722
NM_006005.3(WFS1):c.*274A>G rs1046325 0.08190
NM_006005.3(WFS1):c.2322G>A (p.Lys774=) rs2230721 0.06809
NM_006005.3(WFS1):c.713-1360G>A rs61251604 0.05371
NM_006005.3(WFS1):c.*241T>C rs60985011 0.05284
NM_006005.3(WFS1):c.1023C>T (p.Phe341=) rs56072215 0.04932
NM_006005.3(WFS1):c.316-235C>G rs56141488 0.04351
NM_006005.3(WFS1):c.713-945A>G rs116109951 0.03694
NM_006005.3(WFS1):c.713-1219C>T rs112592966 0.03211
NM_006005.3(WFS1):c.1805C>T (p.Ala602Val) rs2230720 0.02889
NM_006005.3(WFS1):c.*567C>G rs12508118 0.02697
NM_006005.3(WFS1):c.*333C>A rs111800114 0.02051
NM_006005.3(WFS1):c.631+164G>C rs71539643 0.01831
NM_006005.3(WFS1):c.*637T>C rs71528901 0.01713
NM_006005.3(WFS1):c.*54A>G rs71526455 0.01704
NM_006005.3(WFS1):c.*512C>T rs71528900 0.01701
NM_006005.3(WFS1):c.2019C>T (p.Cys673=) rs71524375 0.01683
NM_006005.3(WFS1):c.9C>T (p.Ser3=) rs71524363 0.01435
NM_006005.3(WFS1):c.713-231G>A rs112272637 0.01258
NM_006005.3(WFS1):c.*131C>T rs55993016 0.01227
NM_006005.3(WFS1):c.461-91G>A rs71539642 0.01155
NM_006005.3(WFS1):c.1800C>T (p.Thr600=) rs71524362 0.01070
NM_006005.3(WFS1):c.930A>G (p.Ala310=) rs115561278 0.00845
NM_006005.3(WFS1):c.1308C>T (p.Thr436=) rs71539646 0.00773
NM_006005.3(WFS1):c.2247G>A (p.Thr749=) rs75096624 0.00513
NM_006005.3(WFS1):c.*242G>C rs80055761 0.00471
NM_006005.3(WFS1):c.-6+11C>T rs547998667 0.00469
NM_006005.3(WFS1):c.-264A>G rs71537683 0.00428
NM_006005.3(WFS1):c.225C>T (p.Asp75=) rs35216268 0.00366
NM_006005.3(WFS1):c.*358T>C rs71530919 0.00289
NM_006005.3(WFS1):c.1674C>T (p.Arg558=) rs61735402 0.00269
NM_006005.3(WFS1):c.*69C>T rs71530916 0.00257
NM_006005.3(WFS1):c.1158C>T (p.Pro386=) rs71524354 0.00252
NM_006005.3(WFS1):c.*288C>T rs56072224 0.00248
NM_006005.3(WFS1):c.2356G>A (p.Gly786Ser) rs71578980 0.00239
NM_006005.3(WFS1):c.712+16G>A rs71524367 0.00213
NM_006005.3(WFS1):c.227G>T (p.Gly76Val) rs200135768 0.00197
NM_006005.3(WFS1):c.1530C>T (p.Tyr510=) rs35789242 0.00183
NM_006005.3(WFS1):c.1491C>T (p.Val497=) rs148310584 0.00151
NM_006005.3(WFS1):c.2052G>A (p.Ala684=) rs71539668 0.00123
NM_006005.3(WFS1):c.96G>A (p.Ser32=) rs71539660 0.00106
NM_006005.3(WFS1):c.1683C>T (p.Ile561=) rs71530906 0.00086
NM_006005.3(WFS1):c.2184C>T (p.Gly728=) rs71530908 0.00084
NM_006005.3(WFS1):c.966C>T (p.His322=) rs140196582 0.00083
NM_006005.3(WFS1):c.631+12C>T rs183980454 0.00082
NM_006005.3(WFS1):c.*448A>T rs113513950 0.00076
NM_006005.3(WFS1):c.2233G>A (p.Gly745Ser) rs139185707 0.00068
NM_006005.3(WFS1):c.363C>T (p.Leu121=) rs140229545 0.00067
NM_006005.3(WFS1):c.*80C>T rs183014938 0.00065
NM_006005.3(WFS1):c.*520G>A rs573433508 0.00051
NM_006005.3(WFS1):c.*263T>G rs571223325 0.00048
NM_006005.3(WFS1):c.2424C>T (p.Ser808=) rs56035336 0.00048
NM_006005.3(WFS1):c.2202C>T (p.Leu734=) rs140427062 0.00041
NM_006005.3(WFS1):c.402G>A (p.Ala134=) rs199533137 0.00040
NM_006005.3(WFS1):c.594G>A (p.Ala198=) rs563931269 0.00031
NM_006005.3(WFS1):c.*300A>G rs541125786 0.00030
NM_006005.3(WFS1):c.2436C>T (p.Ser812=) rs142630687 0.00030
NM_006005.3(WFS1):c.1470C>T (p.Thr490=) rs146027767 0.00025
NM_006005.3(WFS1):c.*455A>G rs756674774 0.00024
NM_006005.3(WFS1):c.1419C>T (p.Ser473=) rs150997327 0.00024
NM_006005.3(WFS1):c.2250C>T (p.Ala750=) rs369498603 0.00023
NM_006005.3(WFS1):c.1302C>T (p.Val434=) rs142745931 0.00021
NM_006005.3(WFS1):c.1758C>T (p.Ala586=) rs145144527 0.00021
NM_006005.3(WFS1):c.2012C>T (p.Ala671Val) rs71530907 0.00021
NM_006005.3(WFS1):c.2563T>C (p.Ser855Pro) rs141833472 0.00021
NM_006005.3(WFS1):c.1632C>T (p.Ser544=) rs140115060 0.00020
NM_006005.3(WFS1):c.712+8C>T rs369185545 0.00020
NM_006005.3(WFS1):c.762C>T (p.Tyr254=) rs140266808 0.00020
NM_006005.3(WFS1):c.1695C>T (p.Leu565=) rs755736687 0.00019
NM_006005.3(WFS1):c.2466C>A (p.Leu822=) rs141669724 0.00019
NM_006005.3(WFS1):c.1923G>A (p.Thr641=) rs139040290 0.00018
NM_006005.3(WFS1):c.2622C>T (p.Ala874=) rs141052196 0.00018
NM_006005.3(WFS1):c.1755C>T (p.Phe585=) rs1801210 0.00017
NM_006005.3(WFS1):c.975C>T (p.Asn325=) rs141177727 0.00017
NM_006005.3(WFS1):c.1441C>T (p.Leu481=) rs727504663 0.00016
NM_006005.3(WFS1):c.2013G>A (p.Ala671=) rs147262416 0.00016
NM_006005.3(WFS1):c.471C>T (p.Ser157=) rs71524347 0.00016
NM_006005.3(WFS1):c.801C>T (p.Asp267=) rs147734431 0.00016
NM_006005.3(WFS1):c.825G>A (p.Ala275=) rs566634291 0.00016
NM_006005.3(WFS1):c.2667G>A (p.Ala889=) rs71526454 0.00015
NM_006005.3(WFS1):c.1399C>T (p.Leu467=) rs142700542 0.00014
NM_006005.3(WFS1):c.2040G>A (p.Glu680=) rs375263408 0.00014
NM_006005.3(WFS1):c.1173G>A (p.Glu391=) rs202104460 0.00013
NM_006005.3(WFS1):c.2610C>T (p.Thr870=) rs727503754 0.00013
NM_006005.3(WFS1):c.1395C>T (p.Ala465=) rs71530905 0.00012
NM_006005.3(WFS1):c.1452T>G (p.Leu484=) rs371470711 0.00009
NM_006005.3(WFS1):c.1770G>A (p.Thr590=) rs71532858 0.00009
NM_006005.3(WFS1):c.2631C>T (p.Phe877=) rs370347920 0.00009
NM_006005.3(WFS1):c.315+12G>A rs370922505 0.00009
NM_006005.3(WFS1):c.2103C>T (p.Thr701=) rs113800346 0.00008
NM_006005.3(WFS1):c.129A>T (p.Ala43=) rs566876793 0.00007
NM_006005.3(WFS1):c.1740G>T (p.Val580=) rs749882923 0.00007
NM_006005.3(WFS1):c.21G>T (p.Pro7=) rs372928810 0.00007
NM_006005.3(WFS1):c.291C>T (p.Ala97=) rs148404077 0.00007
NM_006005.3(WFS1):c.342C>T (p.Ala114=) rs201151892 0.00007
NM_006005.3(WFS1):c.396C>T (p.Leu132=) rs369759802 0.00007
NM_006005.3(WFS1):c.726C>T (p.Ile242=) rs71524381 0.00007
NM_006005.3(WFS1):c.*654G>A rs886059539 0.00006
NM_006005.3(WFS1):c.1392C>T (p.Thr464=) rs565697340 0.00006
NM_006005.3(WFS1):c.1479C>T (p.Val493=) rs750126396 0.00006
NM_006005.3(WFS1):c.1656C>T (p.Thr552=) rs141477172 0.00006
NM_006005.3(WFS1):c.1791C>T (p.Ile597=) rs141883293 0.00006
NM_006005.3(WFS1):c.2181C>T (p.Ile727=) rs140286718 0.00006
NM_006005.3(WFS1):c.2208C>T (p.Gly736=) rs141020933 0.00006
NM_006005.3(WFS1):c.231C>T (p.Thr77=) rs372609400 0.00006
NM_006005.3(WFS1):c.2358C>T (p.Gly786=) rs139236812 0.00006
NM_006005.3(WFS1):c.2445C>G (p.Leu815=) rs376195481 0.00006
NM_006005.3(WFS1):c.28C>T (p.Pro10Ser) rs760256649 0.00006
NM_006005.3(WFS1):c.504C>T (p.Ser168=) rs71537675 0.00006
NM_006005.3(WFS1):c.642G>A (p.Ala214=) rs761245713 0.00006
NM_006005.3(WFS1):c.69G>A (p.Ala23=) rs750859280 0.00006
NM_006005.3(WFS1):c.*158G>A rs548892128 0.00005
NM_006005.3(WFS1):c.2397C>G (p.Thr799=) rs747760206 0.00005
NM_006005.3(WFS1):c.477C>T (p.Asn159=) rs753964845 0.00005
NM_006005.3(WFS1):c.498C>G (p.Leu166=) rs758731318 0.00005
NM_006005.3(WFS1):c.*506C>T rs886059536 0.00004
NM_006005.3(WFS1):c.1080C>T (p.Cys360=) rs771284690 0.00004
NM_006005.3(WFS1):c.1237T>G (p.Phe413Val) rs71524356 0.00004
NM_006005.3(WFS1):c.1242C>T (p.Phe414=) rs376646736 0.00004
NM_006005.3(WFS1):c.1320C>T (p.Thr440=) rs762339922 0.00004
NM_006005.3(WFS1):c.1507G>A (p.Val503Ile) rs573775230 0.00004
NM_006005.3(WFS1):c.168C>T (p.Asp56=) rs112598170 0.00004
NM_006005.3(WFS1):c.1743C>T (p.Gly581=) rs377539343 0.00004
NM_006005.3(WFS1):c.1801G>A (p.Val601Met) rs147838635 0.00004
NM_006005.3(WFS1):c.1929C>T (p.Ile643=) rs544473222 0.00004
NM_006005.3(WFS1):c.2334C>T (p.Thr778=) rs71526460 0.00004
NM_006005.3(WFS1):c.2355C>T (p.Ser785=) rs201731358 0.00004
NM_006005.3(WFS1):c.2607C>T (p.Ser869=) rs1410561677 0.00004
NM_006005.3(WFS1):c.2664G>A (p.Ser888=) rs756116434 0.00004
NM_006005.3(WFS1):c.315+11C>T rs202232817 0.00004
NM_006005.3(WFS1):c.375C>T (p.Thr125=) rs762324196 0.00004
NM_006005.3(WFS1):c.*605T>C rs886059538 0.00003
NM_006005.3(WFS1):c.*700C>A rs528424908 0.00003
NM_006005.3(WFS1):c.1125C>T (p.Arg375=) rs778100722 0.00003
NM_006005.3(WFS1):c.1263C>T (p.Ile421=) rs748103155 0.00003
NM_006005.3(WFS1):c.1680C>T (p.Ser560=) rs760906868 0.00003
NM_006005.3(WFS1):c.1761G>C (p.Arg587=) rs35568345 0.00003
NM_006005.3(WFS1):c.1824G>A (p.Leu608=) rs1224321509 0.00003
NM_006005.3(WFS1):c.1884G>A (p.Thr628=) rs71532860 0.00003
NM_006005.3(WFS1):c.2011G>T (p.Ala671Ser) rs763020615 0.00003
NM_006005.3(WFS1):c.2406C>T (p.Ile802=) rs201102144 0.00003
NM_006005.3(WFS1):c.399C>T (p.Ala133=) rs757294266 0.00003
NM_006005.3(WFS1):c.787C>T (p.Leu263=) rs749765315 0.00003
NM_006005.3(WFS1):c.1290G>A (p.Ser430=) rs752100338 0.00002
NM_006005.3(WFS1):c.1425C>T (p.Pro475=) rs370846103 0.00002
NM_006005.3(WFS1):c.1863G>C (p.Val621=) rs779337227 0.00002
NM_006005.3(WFS1):c.1935G>T (p.Leu645=) rs727504912 0.00002
NM_006005.3(WFS1):c.2157C>T (p.Ala719=) rs766900991 0.00002
NM_006005.3(WFS1):c.2540G>A (p.Cys847Tyr) rs1394576939 0.00002
NM_006005.3(WFS1):c.345C>T (p.Gly115=) rs200385504 0.00002
NM_006005.3(WFS1):c.57G>A (p.Pro19=) rs1282394241 0.00002
NM_006005.3(WFS1):c.981C>T (p.Leu327=) rs1257021150 0.00002
NM_006005.3(WFS1):c.*11C>G rs919707549 0.00001
NM_006005.3(WFS1):c.*14C>T rs775493668 0.00001
NM_006005.3(WFS1):c.*223C>G rs905909594 0.00001
NM_006005.3(WFS1):c.*37C>A rs1312854010 0.00001
NM_006005.3(WFS1):c.*656C>T rs772538455 0.00001
NM_006005.3(WFS1):c.1236C>T (p.Val412=) rs753290200 0.00001
NM_006005.3(WFS1):c.125G>A (p.Arg42Gln) rs750806151 0.00001
NM_006005.3(WFS1):c.1335G>C (p.Leu445=) rs1426049330 0.00001
NM_006005.3(WFS1):c.1416C>A (p.Pro472=) rs530734300 0.00001
NM_006005.3(WFS1):c.1536C>T (p.Leu512=) rs199728640 0.00001
NM_006005.3(WFS1):c.234G>C (p.Gly78=) rs1205134261 0.00001
NM_006005.3(WFS1):c.2454C>T (p.Arg818=) rs139223980 0.00001
NM_006005.3(WFS1):c.2532C>T (p.Ala844=) rs767155345 0.00001
NM_006005.3(WFS1):c.2549G>A (p.Cys850Tyr) rs748404777 0.00001
NM_006005.3(WFS1):c.2625G>A (p.Val875=) rs1264608390 0.00001
NM_006005.3(WFS1):c.804C>T (p.Asp268=) rs199741678 0.00001
NM_006005.3(WFS1):c.816C>T (p.Asp272=) rs762774307 0.00001
NC_000004.12:g.6304102C>A rs754802246
NM_006005.3(WFS1):c.*260G>C rs71530909
NM_006005.3(WFS1):c.*526A>C rs886059537
NM_006005.3(WFS1):c.*553G>C rs904935032
NM_006005.3(WFS1):c.-55C>T rs886059525
NM_006005.3(WFS1):c.1020C>T (p.Phe340=) rs876658117
NM_006005.3(WFS1):c.1038G>A (p.Pro346=) rs143886476
NM_006005.3(WFS1):c.1089G>A (p.Lys363=) rs1553878342
NM_006005.3(WFS1):c.1134C>A (p.Thr378=) rs71530904
NM_006005.3(WFS1):c.1149C>T (p.Arg383=) rs1560418384
NM_006005.3(WFS1):c.114C>T (p.Ser38=) rs531593902
NM_006005.3(WFS1):c.1194C>T (p.Gly398=) rs143633587
NM_006005.3(WFS1):c.1233T>G (p.Ser411=) rs760897070
NM_006005.3(WFS1):c.1261A>G (p.Ile421Val) rs727503749
NM_006005.3(WFS1):c.1311C>T (p.Gly437=) rs886059529
NM_006005.3(WFS1):c.132C>T (p.Pro44=) rs754346893
NM_006005.3(WFS1):c.1333C>G (p.Leu445Val) rs764932308
NM_006005.3(WFS1):c.1350T>C (p.His450=) rs1057521190
NM_006005.3(WFS1):c.1461C>T (p.Thr487=) rs771363371
NM_006005.3(WFS1):c.1503C>T (p.Val501=) rs768245959
NM_006005.3(WFS1):c.1509C>T (p.Val503=) rs1267751619
NM_006005.3(WFS1):c.1653C>T (p.Ser551=) rs766730980
NM_006005.3(WFS1):c.169G>A (p.Ala57Thr) rs372783392
NM_006005.3(WFS1):c.172G>A (p.Ala58Thr) rs1057524887
NM_006005.3(WFS1):c.1797C>A (p.Val599=) rs71524361
NM_006005.3(WFS1):c.1806G>A (p.Ala602=) rs142295878
NM_006005.3(WFS1):c.1818G>A (p.Val606=) rs1553878726
NM_006005.3(WFS1):c.1829del (p.Leu610fs) rs1578611240
NM_006005.3(WFS1):c.2001G>A (p.Gln667=) rs769778558
NM_006005.3(WFS1):c.2158A>G (p.Ile720Val) rs1805070
NM_006005.3(WFS1):c.2337G>A (p.Val779=) rs1299034736
NM_006005.3(WFS1):c.2340C>A (p.Gly780=) rs886059531
NM_006005.3(WFS1):c.2370G>A (p.Ser790=) rs150936382
NM_006005.3(WFS1):c.2481C>T (p.Thr827=) rs886059532
NM_006005.3(WFS1):c.2514T>C (p.Pro838=) rs773643250
NM_006005.3(WFS1):c.2595C>T (p.His865=) rs142469572
NM_006005.3(WFS1):c.316-14T>G rs749922151
NM_006005.3(WFS1):c.350C>T (p.Thr117Met) rs141225426
NM_006005.3(WFS1):c.468G>A (p.Thr156=) rs201145164
NM_006005.3(WFS1):c.510C>G (p.Thr170=) rs151277039
NM_006005.3(WFS1):c.615C>T (p.Gly205=) rs954971844
NM_006005.3(WFS1):c.654C>T (p.Pro218=) rs727504666
NM_006005.3(WFS1):c.713-1024A>T rs28625666
NM_006005.3(WFS1):c.713-1317A>T rs10937720
NM_006005.3(WFS1):c.81C>G (p.Leu27=) rs777168956
NM_006005.3(WFS1):c.837T>G (p.Pro279=) rs762770133
NM_006005.3(WFS1):c.924C>T (p.Ser308=) rs763063215

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