List of variants in gene MLH1 reported as benign by Ambry Genetics

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 36

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HGVS	dbSNP	gnomAD frequency
NM_000249.4(MLH1):c.1668-19A>G	rs9876116	0.41821
NM_000249.4(MLH1):c.655A>G (p.Ile219Val)	rs1799977	0.23048
NM_000249.3(MLH1):c.-93G>A	rs1800734	0.22121
NM_000249.4(MLH1):c.1558+14G>A	rs41562513	0.05554
NM_000249.4(MLH1):c.2152C>T (p.His718Tyr)	rs2020873	0.02345
NM_000249.4(MLH1):c.474C>T (p.Asn158=)	rs4647256	0.01161
NM_000249.4(MLH1):c.1039-8T>A	rs193922367	0.01153
NM_000249.4(MLH1):c.588+11G>C	rs4647258	0.00993
NM_000249.4(MLH1):c.1732-19T>A	rs77120160	0.00923
NM_000249.4(MLH1):c.1959G>T (p.Leu653=)	rs1800146	0.00913
NM_000249.4(MLH1):c.637G>A (p.Val213Met)	rs2308317	0.00818
NM_000249.4(MLH1):c.1038+51C>T	rs55986674	0.00582
NM_000249.4(MLH1):c.589-15C>T	rs55658850	0.00582
NM_000249.4(MLH1):c.545+20A>T	rs121909453	0.00424
NM_000249.4(MLH1):c.1852A>G (p.Lys618Glu)	rs35001569	0.00399
NM_000249.4(MLH1):c.1963A>G (p.Ile655Val)	rs55907433	0.00297
NM_000249.4(MLH1):c.790+10A>G	rs182733777	0.00188
NM_000249.4(MLH1):c.2146G>A (p.Val716Met)	rs35831931	0.00143
NM_000249.4(MLH1):c.1217G>A (p.Ser406Asn)	rs41294980	0.00087
NM_000249.4(MLH1):c.1151T>A (p.Val384Asp)	rs63750447	0.00077
NM_000249.4(MLH1):c.1321G>A (p.Ala441Thr)	rs63750365	0.00034
NM_000249.4(MLH1):c.2066A>G (p.Gln689Arg)	rs63750702	0.00022
NM_000249.4(MLH1):c.307-19A>G	rs121909451	0.00022
NM_000249.4(MLH1):c.1040C>A (p.Thr347Asn)	rs201541505	0.00017
NM_000249.4(MLH1):c.2101C>A (p.Gln701Lys)	rs63750114	0.00016
NM_000249.4(MLH1):c.1742C>T (p.Pro581Leu)	rs63751684	0.00008
NM_000249.4(MLH1):c.1730C>T (p.Ser577Leu)	rs56185292	0.00003
NM_000249.4(MLH1):c.303T>G (p.Gly101=)	rs4647220	0.00002
NM_000249.4(MLH1):c.1039-6dup	rs1553650466
NM_000249.4(MLH1):c.1039-8_1039-7insTA	rs535965616
NM_000249.4(MLH1):c.1136A>C (p.Tyr379Ser)	rs143009528
NM_000249.4(MLH1):c.1487C>G (p.Pro496Arg)	rs63750226
NM_000249.4(MLH1):c.1852_1853delinsGC (p.Lys618Ala)	rs35502531
NM_000249.4(MLH1):c.1853A>C (p.Lys618Thr)	rs63750449
NM_000249.4(MLH1):c.1978C>T (p.Leu660=)	rs752427924
NM_000249.4(MLH1):c.290A>G (p.Tyr97Cys)	rs773647920

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