List of variants in gene MSH6 reported as benign by Ambry Genetics

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 34

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HGVS	dbSNP	gnomAD frequency
NM_000179.3(MSH6):c.3438+14A>T	rs2020911	0.32279
NM_000179.3(MSH6):c.540T>C (p.Asp180=)	rs1800935	0.23857
NM_000179.3(MSH6):c.116G>A (p.Gly39Glu)	rs1042821	0.18742
NM_000179.3(MSH6):c.276A>G (p.Pro92=)	rs1800932	0.14697
NM_000179.3(MSH6):c.186C>A (p.Arg62=)	rs1042820	0.12806
NM_000179.3(MSH6):c.642C>T (p.Tyr214=)	rs1800937	0.07457
NM_000179.3(MSH6):c.2253T>C (p.Asn751=)	rs2020913	0.02003
NM_000179.3(MSH6):c.1164C>T (p.His388=)	rs55708305	0.01384
NM_000179.3(MSH6):c.2272C>T (p.Leu758=)	rs56371757	0.01363
NM_000179.3(MSH6):c.3306T>A (p.Thr1102=)	rs2020910	0.00869
NM_000179.3(MSH6):c.1186C>G (p.Leu396Val)	rs2020908	0.00565
NM_000179.3(MSH6):c.2633T>C (p.Val878Ala)	rs2020912	0.00448
NM_000179.3(MSH6):c.457+13A>G	rs1800933	0.00434
NM_000179.3(MSH6):c.1345C>T (p.Leu449=)	rs3136333	0.00429
NM_000179.3(MSH6):c.3911G>A (p.Arg1304Lys)	rs34625968	0.00253
NM_000179.3(MSH6):c.3439-16C>T	rs192614006	0.00237
NM_000179.3(MSH6):c.431G>T (p.Ser144Ile)	rs3211299	0.00158
NM_000179.3(MSH6):c.3265T>C (p.Leu1089=)	rs34490141	0.00096
NM_000179.3(MSH6):c.1526T>C (p.Val509Ala)	rs63751005	0.00067
NM_000179.3(MSH6):c.663A>C (p.Glu221Asp)	rs41557217	0.00064
NM_000179.3(MSH6):c.1508C>G (p.Ser503Cys)	rs63750897	0.00059
NM_000179.3(MSH6):c.3488A>T (p.Glu1163Val)	rs63750252	0.00032
NM_000179.3(MSH6):c.3217C>T (p.Pro1073Ser)	rs142254875	0.00028
NM_000179.3(MSH6):c.3438+11_3438+14del	rs377746844	0.00023
NM_000179.3(MSH6):c.3172+20T>C	rs3136335	0.00009
NM_000179.3(MSH6):c.1050C>T (p.Ala350=)	rs730881802	0.00006
NM_000179.3(MSH6):c.3557-3A>T	rs41295274	0.00004
NM_000179.3(MSH6):c.3151G>A (p.Val1051Ile)	rs576269342
NM_000179.3(MSH6):c.3173-18T>A	rs189672273
NM_000179.3(MSH6):c.3190G>A (p.Ala1064Thr)	rs587782492
NM_000179.3(MSH6):c.3259C>A (p.Pro1087Thr)	rs63750998
NM_000179.3(MSH6):c.3557-5_3557-4dup	rs267608102
NM_000179.3(MSH6):c.4068_4071dup (p.Lys1358delinsAspTer)	rs55740729
NM_000179.3(MSH6):c.628-4G>C	rs1572719700

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