List of variants in gene VCL reported as likely benign by Ambry Genetics

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 109

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_014000.3(VCL):c.2025G>A (p.Val675=)	rs140766884	0.00256
NM_014000.3(VCL):c.1907A>G (p.His636Arg)	rs71579374	0.00240
NM_014000.3(VCL):c.660C>T (p.Asn220=)	rs56264452	0.00091
NM_014000.3(VCL):c.1572C>T (p.Ala524=)	rs138566234	0.00086
NM_014000.3(VCL):c.1348A>C (p.Arg450=)	rs142128712	0.00075
NM_014000.3(VCL):c.1555A>C (p.Ile519Leu)	rs141033098	0.00064
NM_014000.3(VCL):c.1237G>A (p.Ala413Thr)	rs146278697	0.00044
NM_014000.3(VCL):c.1626C>T (p.Leu542=)	rs150402791	0.00031
NM_014000.3(VCL):c.366G>A (p.Leu122=)	rs199562976	0.00029
NM_014000.3(VCL):c.1297C>T (p.Arg433Cys)	rs139559937	0.00026
NM_014000.3(VCL):c.787A>T (p.Thr263Ser)	rs142233726	0.00022
NM_014000.3(VCL):c.1788A>C (p.Ser596=)	rs199582103	0.00021
NM_014000.3(VCL):c.571T>C (p.Leu191=)	rs370334093	0.00021
NM_014000.3(VCL):c.2427C>T (p.Ser809=)	rs183739128	0.00019
NM_014000.3(VCL):c.590C>T (p.Thr197Ile)	rs189242810	0.00019
NM_014000.3(VCL):c.1716T>G (p.Leu572=)	rs189781480	0.00016
NM_014000.3(VCL):c.1842G>A (p.Thr614=)	rs144117013	0.00016
NM_014000.3(VCL):c.2827C>G (p.Pro943Ala)	rs71579375	0.00013
NM_014000.3(VCL):c.2796T>C (p.Asp932=)	rs140308982	0.00012
NM_014000.3(VCL):c.378C>T (p.Phe126=)	rs148966602	0.00012
NM_014000.3(VCL):c.2655C>T (p.Phe885=)	rs149196315	0.00011
NM_014000.3(VCL):c.1290C>T (p.Asp430=)	rs576271894	0.00009
NM_014000.3(VCL):c.1329T>C (p.Ser443=)	rs142350240	0.00009
NM_014000.3(VCL):c.2142C>T (p.Asp714=)	rs373790383	0.00009
NM_014000.3(VCL):c.3066C>T (p.Ile1022=)	rs138619320	0.00009
NM_014000.3(VCL):c.3102G>A (p.Lys1034=)	rs373584575	0.00009
NM_014000.3(VCL):c.3333T>C (p.Ala1111=)	rs147415627	0.00008
NM_014000.3(VCL):c.2802C>T (p.Ala934=)	rs372381809	0.00007
NM_014000.3(VCL):c.404T>C (p.Ile135Thr)	rs373744314	0.00006
NM_014000.3(VCL):c.528C>T (p.Asp176=)	rs746453891	0.00005
NM_014000.3(VCL):c.1177-5T>C	rs370860265	0.00004
NM_014000.3(VCL):c.1206G>A (p.Pro402=)	rs779265817	0.00004
NM_014000.3(VCL):c.2028C>G (p.Val676=)	rs528539468	0.00004
NM_014000.3(VCL):c.2418A>G (p.Gly806=)	rs538142998	0.00004
NM_014000.3(VCL):c.2472C>G (p.Ile824Met)	rs140381835	0.00004
NM_014000.3(VCL):c.255C>T (p.Cys85=)	rs117384664	0.00004
NM_014000.3(VCL):c.2652G>A (p.Glu884=)	rs371187988	0.00004
NM_014000.3(VCL):c.1041G>C (p.Pro347=)	rs373079313	0.00003
NM_014000.3(VCL):c.225A>G (p.Pro75=)	rs759937112	0.00003
NM_014000.3(VCL):c.1170T>C (p.Ala390=)	rs201459260	0.00002
NM_014000.3(VCL):c.1857G>A (p.Ala619=)	rs1402201354	0.00002
NM_014000.3(VCL):c.2670C>T (p.Ala890=)	rs748291846	0.00002
NM_014000.3(VCL):c.2847C>T (p.Tyr949=)	rs770857763	0.00002
NM_014000.3(VCL):c.3375C>T (p.Arg1125=)	rs12573090	0.00002
NM_014000.3(VCL):c.582G>A (p.Ser194=)	rs773725513	0.00002
NM_014000.3(VCL):c.1458G>A (p.Pro486=)	rs767968937	0.00001
NM_014000.3(VCL):c.1497A>G (p.Gln499=)	rs986960406	0.00001
NM_014000.3(VCL):c.1563G>C (p.Gly521=)	rs747932867	0.00001
NM_014000.3(VCL):c.1767G>A (p.Glu589=)	rs878854971	0.00001
NM_014000.3(VCL):c.1845G>A (p.Ala615=)	rs749812890	0.00001
NM_014000.3(VCL):c.1932C>T (p.Ala644=)	rs762594014	0.00001
NM_014000.3(VCL):c.1941G>A (p.Ala647=)	rs1840045095	0.00001
NM_014000.3(VCL):c.1947G>A (p.Ala649=)	rs200168992	0.00001
NM_014000.3(VCL):c.2019C>T (p.Pro673=)	rs1591709995	0.00001
NM_014000.3(VCL):c.240-4A>G	rs769989314	0.00001
NM_014000.3(VCL):c.2532G>A (p.Pro844=)	rs1428239005	0.00001
NM_014000.3(VCL):c.2601A>G (p.Glu867=)	rs764067327	0.00001
NM_014000.3(VCL):c.2760C>T (p.Ala920=)	rs138594604	0.00001
NM_014000.3(VCL):c.3033C>T (p.Thr1011=)	rs537877002	0.00001
NM_014000.3(VCL):c.3051G>A (p.Gln1017=)	rs756849548	0.00001
NM_014000.3(VCL):c.3186G>A (p.Gln1062=)	rs761534024	0.00001
NM_014000.3(VCL):c.3237C>T (p.Ile1079=)	rs201526599	0.00001
NM_014000.3(VCL):c.3381T>C (p.Val1127=)	rs943734765	0.00001
NM_014000.3(VCL):c.3393C>T (p.Pro1131=)	rs760396103	0.00001
NM_014000.3(VCL):c.723T>C (p.Ile241=)	rs771420978	0.00001
NM_014000.3(VCL):c.780C>T (p.Ser260=)	rs774377548	0.00001
NM_014000.3(VCL):c.1041G>A (p.Pro347=)
NM_014000.3(VCL):c.1095A>G (p.Ala365=)
NM_014000.3(VCL):c.1157A>G (p.Lys386Arg)	rs200342284
NM_014000.3(VCL):c.1272T>C (p.Asp424=)	rs1393816882
NM_014000.3(VCL):c.1296A>G (p.Leu432=)
NM_014000.3(VCL):c.1296_1297inv (p.Arg433Cys)
NM_014000.3(VCL):c.1435C>A (p.Arg479=)	rs369055603
NM_014000.3(VCL):c.1440T>G (p.Ala480=)
NM_014000.3(VCL):c.1494G>A (p.Glu498=)
NM_014000.3(VCL):c.1563G>A (p.Gly521=)
NM_014000.3(VCL):c.1587G>A (p.Leu529=)
NM_014000.3(VCL):c.1641A>G (p.Arg547=)	rs1246258740
NM_014000.3(VCL):c.1824G>C (p.Leu608=)
NM_014000.3(VCL):c.1857G>C (p.Ala619=)
NM_014000.3(VCL):c.1857G>T (p.Ala619=)
NM_014000.3(VCL):c.1896C>T (p.Asn632=)
NM_014000.3(VCL):c.1929G>A (p.Thr643=)
NM_014000.3(VCL):c.195T>C (p.Thr65=)
NM_014000.3(VCL):c.1973T>C (p.Val658Ala)	rs372691803
NM_014000.3(VCL):c.2109C>T (p.Ile703=)	rs1253771786
NM_014000.3(VCL):c.2256G>C (p.Gly752=)	rs1057522615
NM_014000.3(VCL):c.2262C>A (p.Thr754=)
NM_014000.3(VCL):c.2268T>C (p.Ile756=)
NM_014000.3(VCL):c.2275C>A (p.Arg759=)	rs774477633
NM_014000.3(VCL):c.228A>G (p.Pro76=)
NM_014000.3(VCL):c.2304G>A (p.Lys768=)
NM_014000.3(VCL):c.2577T>C (p.Ala859=)
NM_014000.3(VCL):c.261G>A (p.Lys87=)	rs1057523799
NM_014000.3(VCL):c.2769G>A (p.Val923=)	rs1057521313
NM_014000.3(VCL):c.2784A>G (p.Val928=)	rs752985431
NM_014000.3(VCL):c.2862_2864del (p.Leu955del)	rs397517237
NM_014000.3(VCL):c.2895C>T (p.Pro965=)
NM_014000.3(VCL):c.300C>T (p.Tyr100=)
NM_014000.3(VCL):c.3024C>A (p.Gly1008=)	rs2131939835
NM_014000.3(VCL):c.3246G>A (p.Glu1082=)	rs988135144
NM_014000.3(VCL):c.3375C>A (p.Arg1125=)
NM_014000.3(VCL):c.354A>C (p.Gly118=)
NM_014000.3(VCL):c.480C>T (p.Tyr160=)	rs2136272917
NM_014000.3(VCL):c.622+4C>T	rs201020802
NM_014000.3(VCL):c.705A>G (p.Glu235=)
NM_014000.3(VCL):c.789T>C (p.Thr263=)	rs538002543
NM_014000.3(VCL):c.837G>A (p.Gln279=)
NM_014000.3(VCL):c.875-4T>G

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.