ClinVar Miner

Variants with conflicting interpretations studied for Cardiac arrhythmia, ankyrin B-related

Coded as:
Minimum review status of the submission for Cardiac arrhythmia, ankyrin B-related: Y axis collection method of the submission for Cardiac arrhythmia, ankyrin B-related:
Minimum review status of the other submission: Collection method of the other submission:
Minimum conflict level:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
5 11 0 17 11 0 3 26

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

All conditions
Cardiac arrhythmia, ankyrin B-related pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 2 3 1
likely pathogenic 1 0 1 1 0
uncertain significance 1 1 0 3 2
likely benign 0 0 7 0 8
benign 0 0 2 11 0

Condition to condition summary #

Total conditions: 8
Download table as spreadsheet
Condition Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
Long QT syndrome 0 9 0 16 8 0 3 23
Cardiovascular phenotype 0 12 0 5 3 0 3 11
not provided 0 12 0 3 2 0 3 8
not specified 0 15 0 4 3 0 1 8
Cardiac arrhythmia 0 0 0 1 1 0 2 4
Cardiac arrhythmia, ankyrin B-related 37 1 0 4 0 0 1 4
Cardiac arrest 0 0 0 0 1 0 0 1
Long QT syndrome 4 0 0 0 1 0 0 1 1

All variants with conflicting interpretations #

Total variants: 26
Download table as spreadsheet
HGVS dbSNP
NM_001148.4(ANK2):c.*7C>T rs35446871
NM_001148.4(ANK2):c.10371G>A (p.Thr3457=) rs142908806
NM_001148.4(ANK2):c.11218C>A (p.Leu3740Ile) rs35530544
NM_001148.4(ANK2):c.11231C>A (p.Thr3744Asn) rs121912705
NM_001148.4(ANK2):c.11673T>C (p.His3891=) rs2293324
NM_001148.4(ANK2):c.11791G>A (p.Glu3931Lys) rs45454496
NM_001148.4(ANK2):c.1401A>G (p.Ala467=) rs142159132
NM_001148.4(ANK2):c.2060A>G (p.Asn687Ser) rs29372
NM_001148.4(ANK2):c.2277+9C>T rs141965666
NM_001148.4(ANK2):c.2278-11G>A rs146312675
NM_001148.4(ANK2):c.2377-8C>T rs139893914
NM_001148.4(ANK2):c.3379+12T>G rs139528815
NM_001148.4(ANK2):c.4373A>G (p.Glu1458Gly) rs72544141
NM_001148.4(ANK2):c.4745G>A (p.Arg1582Gln) rs138842207
NM_001148.4(ANK2):c.5469C>T (p.Pro1823=) rs33966911
NM_001148.4(ANK2):c.6176C>T (p.Thr2059Met) rs200765866
NM_001148.4(ANK2):c.6206G>A (p.Arg2069His) rs149645600
NM_001148.4(ANK2):c.7106T>C (p.Val2369Ala) rs28377576
NM_001148.4(ANK2):c.7110A>G (p.Gln2370=) rs3733615
NM_001148.4(ANK2):c.7132G>A (p.Glu2378Lys) rs141191319
NM_001148.4(ANK2):c.8354C>T (p.Ser2785Leu) rs145895389
NM_001148.4(ANK2):c.8843C>G (p.Ala2948Gly) rs138438183
NM_001148.4(ANK2):c.9526G>T (p.Asp3176Tyr) rs138928206
NM_001148.4(ANK2):c.9648A>G (p.Glu3216=) rs10013743
NM_001148.4(ANK2):c.9854T>C (p.Ile3285Thr) rs36210417
NM_001148.4(ANK2):c.9900C>A (p.Ser3300Arg) rs34270799

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.