ClinVar Miner

Variants with conflicting interpretations studied for FLNB-Related Spectrum Disorders

Coded as:
Minimum review status of the submission for FLNB-Related Spectrum Disorders: Y axis collection method of the submission for FLNB-Related Spectrum Disorders:
Minimum review status of the other submission: Collection method of the other submission:
Minimum conflict level:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
88 8 0 31 3 0 0 34

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

All conditions
FLNB-Related Spectrum Disorders likely benign benign
uncertain significance 3 0
likely benign 0 31

Condition to condition summary #

Total conditions: 2
Download table as spreadsheet
Condition Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
not specified 0 4 0 31 3 0 0 34
not provided 0 5 0 4 0 0 0 4

All variants with conflicting interpretations #

Total variants: 34
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HGVS dbSNP
NM_001457.4(FLNB):c.-31C>T rs138060096
NM_001457.4(FLNB):c.1611-4G>A rs73074072
NM_001457.4(FLNB):c.1869C>T (p.Asp623=) rs2140104
NM_001457.4(FLNB):c.1919C>T (p.Thr640Met) rs62621999
NM_001457.4(FLNB):c.2382C>T (p.Asp794=) rs146159035
NM_001457.4(FLNB):c.249G>A (p.Ala83=) rs112750785
NM_001457.4(FLNB):c.2907G>A (p.Arg969=) rs138449267
NM_001457.4(FLNB):c.292+8C>A rs9831243
NM_001457.4(FLNB):c.2935G>A (p.Val979Met) rs376511120
NM_001457.4(FLNB):c.3469G>A (p.Asp1157Asn) rs1131356
NM_001457.4(FLNB):c.3535G>A (p.Glu1179Lys) rs17058845
NM_001457.4(FLNB):c.3724+36del rs56147140
NM_001457.4(FLNB):c.3771G>A (p.Pro1257=) rs146851485
NM_001457.4(FLNB):c.3857C>T (p.Ala1286Val) rs62621997
NM_001457.4(FLNB):c.4062-5T>G rs3732632
NM_001457.4(FLNB):c.4173A>G (p.Ala1391=) rs2362903
NM_001457.4(FLNB):c.4221C>T (p.Pro1407=) rs2362904
NM_001457.4(FLNB):c.4390+8T>A rs377095569
NM_001457.4(FLNB):c.4411G>A (p.Val1471Met) rs12632456
NM_001457.4(FLNB):c.4872C>T (p.Ile1624=) rs147426569
NM_001457.4(FLNB):c.5091C>T (p.Asn1697=) rs141357606
NM_001457.4(FLNB):c.5426-10G>A rs183917041
NM_001457.4(FLNB):c.5646G>A (p.Pro1882=) rs114882667
NM_001457.4(FLNB):c.5769C>T (p.Ala1923=) rs201723447
NM_001457.4(FLNB):c.6017A>G (p.Lys2006Arg) rs62621996
NM_001457.4(FLNB):c.6438G>A (p.Val2146=) rs60599272
NM_001457.4(FLNB):c.6680C>G (p.Ser2227Cys) rs138327769
NM_001457.4(FLNB):c.669G>A (p.Pro223=) rs140815373
NM_001457.4(FLNB):c.6956T>C (p.Ile2319Thr) rs116826041
NM_001457.4(FLNB):c.7099G>A (p.Val2367Ile) rs115747856
NM_001457.4(FLNB):c.7209G>A (p.Ser2403=) rs13079906
NM_001457.4(FLNB):c.7359C>T (p.Ser2453=) rs8640
NM_001457.4(FLNB):c.792C>T (p.Ile264=) rs7623314
NM_001457.4(FLNB):c.927T>C (p.Ser309=) rs1522384

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