ClinVar Miner

Variants with conflicting interpretations studied for Neuroblastoma Susceptibility

Coded as:
Minimum review status of the submission for Neuroblastoma Susceptibility: Y axis collection method of the submission for Neuroblastoma Susceptibility:
Minimum review status of the other submission: Collection method of the other submission:
Minimum conflict level:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
28 23 0 29 11 0 0 40

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

All conditions
Neuroblastoma Susceptibility uncertain significance likely benign benign
uncertain significance 0 7 1
likely benign 3 0 29

Condition to condition summary #

Total conditions: 4
Download table as spreadsheet
Condition Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
Neuroblastoma 3 0 22 0 26 10 0 0 36
Hereditary cancer-predisposing syndrome 0 10 0 14 2 0 0 16
not specified 0 24 0 13 1 0 0 14
not provided 0 14 0 7 0 0 0 7

All variants with conflicting interpretations #

Total variants: 40
Download table as spreadsheet
HGVS dbSNP
NM_004304.5(ALK):c.-5G>A rs56270786
NM_004304.5(ALK):c.1111G>A (p.Ala371Thr) rs149968229
NM_004304.5(ALK):c.1427T>C (p.Val476Ala) rs35093491
NM_004304.5(ALK):c.1464C>T (p.Gly488=) rs56165377
NM_004304.5(ALK):c.1626G>C (p.Pro542=) rs143916398
NM_004304.5(ALK):c.2011C>T (p.Pro671Ser) rs145780832
NM_004304.5(ALK):c.2039C>T (p.Thr680Ile) rs35228363
NM_004304.5(ALK):c.2109C>T (p.Asn703=) rs560163657
NM_004304.5(ALK):c.2127C>A (p.Asn709Lys) rs376175333
NM_004304.5(ALK):c.2133C>T (p.Ser711=) rs77102810
NM_004304.5(ALK):c.2148C>T (p.Ser716=) rs55733526
NM_004304.5(ALK):c.2175C>T (p.Ile725=) rs57881134
NM_004304.5(ALK):c.2210C>T (p.Ser737Leu) rs368581969
NM_004304.5(ALK):c.2430C>T (p.Ser810=) rs150292405
NM_004304.5(ALK):c.2526C>T (p.Ala842=) rs145271283
NM_004304.5(ALK):c.2613C>T (p.Asn871=) rs150557024
NM_004304.5(ALK):c.2676C>T (p.Ala892=) rs138668699
NM_004304.5(ALK):c.3035C>T (p.Thr1012Met) rs35073634
NM_004304.5(ALK):c.3057C>A (p.Val1019=) rs138406372
NM_004304.5(ALK):c.310C>A (p.Pro104Thr) rs576431612
NM_004304.5(ALK):c.3173-11C>T rs79339096
NM_004304.5(ALK):c.3336G>A (p.Pro1112=) rs146074150
NM_004304.5(ALK):c.3408C>T (p.Ser1136=) rs56146053
NM_004304.5(ALK):c.3594C>T (p.Leu1198=) rs56071005
NM_004304.5(ALK):c.3600G>C (p.Ala1200=) rs56247462
NM_004304.5(ALK):c.3633C>A (p.Thr1211=) rs144437923
NM_004304.5(ALK):c.3839C>T (p.Ala1280Val) rs74716434
NM_004304.5(ALK):c.384G>A (p.Lys128=) rs753267950
NM_004304.5(ALK):c.3939-8A>G rs3738869
NM_004304.5(ALK):c.4203T>C (p.Tyr1401=) rs55772745
NM_004304.5(ALK):c.4297_4299GAG[2] (p.Glu1435del) rs138827116
NM_004304.5(ALK):c.4338C>T (p.Thr1446=) rs56132472
NM_004304.5(ALK):c.4344C>T (p.Ser1448=) rs886055929
NM_004304.5(ALK):c.4375G>T (p.Ala1459Ser) rs372612147
NM_004304.5(ALK):c.4573A>G (p.Lys1525Glu) rs139437088
NM_004304.5(ALK):c.4596C>T (p.Asn1532=) rs1881422
NM_004304.5(ALK):c.4836G>A (p.Lys1612=) rs78174819
NM_004304.5(ALK):c.597C>T (p.Gly199=) rs200868013
NM_004304.5(ALK):c.645T>C (p.Leu215=) rs115392387
NM_004304.5(ALK):c.72G>A (p.Gly24=) rs756782371

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