ClinVar Miner

Variants with conflicting interpretations studied for See cases

Minimum review status of the submission for See cases: Y axis collection method of the submission for See cases:
Minimum review status of the other submission: Collection method of the other submission:
Minimum conflict level:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
24151 357 13 14 42 0 30 91

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

All conditions
See cases pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 9 19 3 4
likely pathogenic 10 1 3 1 1
uncertain significance 18 4 11 9 28
likely benign 4 0 11 1 4
benign 4 1 28 4 0

Condition to condition summary #

Total conditions: 3
Download table as spreadsheet
Condition Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
See cases 24225 300 13 13 32 0 24 74
not provided 0 55 1 1 10 0 5 17
Cardiomyopathy; Left ventricular noncompaction; Infantile muscular hypotonia 0 0 0 0 0 0 1 1

All variants with conflicting interpretations #

Total variants: 91
Download table as spreadsheet
HGVS dbSNP
GRCh37/hg19 13q12.12(chr13:23519916-24928440)x1
GRCh37/hg19 13q12.12(chr13:23519916-24936848)x1
GRCh37/hg19 13q12.12(chr13:23519916-24941516)x1
GRCh37/hg19 13q31.3(chr13:92062055-92303438)x1
GRCh37/hg19 15q11.2(chr15:22770421-23195725)x1
GRCh37/hg19 15q11.2(chr15:22770421-23283811)x1
GRCh37/hg19 15q13.2-13.3(chr15:31073735-32444044)x3
GRCh37/hg19 15q26.3(chr15:100614375-100911698)x1
GRCh37/hg19 16p11.2(chr16:28819028-29051191)x3
GRCh37/hg19 16p11.2(chr16:28826162-29043901)x1
GRCh37/hg19 16p11.2(chr16:29580020-30191848)x3
GRCh37/hg19 16p12.2(chr16:21801889-22431357)x3
GRCh37/hg19 16p12.3(chr16:19144340-19281768)x1
GRCh37/hg19 16p13.11(chr16:14897625-16516109)x1
GRCh37/hg19 16p13.11-12.3(chr16:15316618-18185466)x3
GRCh37/hg19 16p13.3(chr16:6294808-6394422)x1
GRCh37/hg19 18q22.1(chr18:65687087-66530088)x4
GRCh37/hg19 1q24.2(chr1:168439652-168712431)x1
GRCh37/hg19 22q11.21(chr22:20716876-21465662)x1
GRCh37/hg19 22q11.21(chr22:20733495-21463730)x1
GRCh37/hg19 22q11.21-11.22(chr22:21029655-22481498)x1
GRCh37/hg19 2p21(chr2:45408934-45976420)x3
GRCh37/hg19 2q21.1(chr2:131477947-131956516)x1
GRCh37/hg19 2q34(chr2:213969855-214925262)x3
GRCh37/hg19 4p16.3-16.1(chr4:68345-8731855)x3
GRCh37/hg19 4q32.3(chr4:164801123-165481802)x3
GRCh37/hg19 6q14.2-14.3(chr6:84373742-85044270)x3
GRCh37/hg19 9p24.3(chr9:611150-694567)x1
GRCh37/hg19 Xp11.3(chrX:43396992-43626868)x2
GRCh38/hg38 10q11.22(chr10:46489780-47923579)x3
GRCh38/hg38 10q11.22-11.23(chr10:45931517-49929364)x1
GRCh38/hg38 10q11.22-11.23(chr10:45999930-49937908)x1
GRCh38/hg38 11q22.1(chr11:97849768-98439058)x1
GRCh38/hg38 12q24.33(chr12:129325762-129943507)x3
GRCh38/hg38 15q11.2(chr15:22572809-23066575)x1
GRCh38/hg38 15q11.2(chr15:22572809-23066575)x3
GRCh38/hg38 15q11.2(chr15:22655582-23066575)x1
GRCh38/hg38 15q11.2(chr15:22655582-23174546)x3
GRCh38/hg38 15q11.2(chr15:22726969-23066575)x3
GRCh38/hg38 15q13.1-13.2(chr15:28694893-30073921)x3
GRCh38/hg38 15q13.2-13.3(chr15:30361674-32607357)x3
GRCh38/hg38 15q13.2-13.3(chr15:30438310-32569425)x3
GRCh38/hg38 15q13.2-13.3(chr15:30438310-32607357)x3
GRCh38/hg38 15q13.3(chr15:31738809-32217725)x3
GRCh38/hg38 15q13.3(chr15:31806467-32134668)x3
GRCh38/hg38 15q26.3(chr15:101686039-101723215)x3
GRCh38/hg38 16p11.2(chr16:29662633-30179247)x3
GRCh38/hg38 16p12.2(chr16:21825971-22396751)x1
GRCh38/hg38 16p12.2(chr16:21826171-22396610)x1
GRCh38/hg38 16p13.11(chr16:14816348-16580464)x3
GRCh38/hg38 17p13.2(chr17:3640170-3656795)x1
GRCh38/hg38 17p13.3(chr17:2599570-2624929)x3
GRCh38/hg38 17q12(chr17:36180741-36266291)x3
GRCh38/hg38 17q25.1(chr17:73851698-74610813)x3
GRCh38/hg38 1q21.1(chr1:145439580-147036021)x3
GRCh38/hg38 1q21.1(chr1:145705541-146009831)x1
GRCh38/hg38 1q21.1(chr1:146987841-148234205)x1
GRCh38/hg38 1q21.1-21.2(chr1:144572470-149076087)x1
GRCh38/hg38 1q21.1-21.2(chr1:145215697-149076087)x3
GRCh38/hg38 1q21.1-21.2(chr1:146964168-148572213)x1
GRCh38/hg38 1q21.1-21.2(chr1:146964168-148572213)x3
GRCh38/hg38 1q21.3(chr1:153641117-153752390)x3
GRCh38/hg38 22q11.21(chr22:18339130-21151128)x1
GRCh38/hg38 22q11.21(chr22:20400132-21086225)x1
GRCh38/hg38 22q11.21(chr22:20400132-21151128)x3
GRCh38/hg38 22q11.21(chr22:20726972-21151128)x3
GRCh38/hg38 22q11.21-11.22(chr22:21454661-22562663)x1
GRCh38/hg38 22q11.22-11.23(chr22:22669543-24563859)x3
GRCh38/hg38 22q11.23(chr22:23377984-24563859)x3
GRCh38/hg38 2p11.2(chr2:87148954-87655401)x3
GRCh38/hg38 2p11.2(chr2:87148954-87705899)x3
GRCh38/hg38 2p22.3(chr2:32452646-33032447)x3
GRCh38/hg38 2p25.3(chr2:30341-507042)x3
GRCh38/hg38 2p25.3(chr2:84669-206271)x1
GRCh38/hg38 2q13(chr2:110104900-110201550)x1
GRCh38/hg38 4q13.2-13.3(chr4:68852530-69850009)x3
GRCh38/hg38 4q35.2(chr4:189111218-189975519)x1
GRCh38/hg38 6q11.1(chr6:61468685-62167348)x3
GRCh38/hg38 7q11.1-11.21(chr7:61006478-62410831)x1
GRCh38/hg38 7q11.1-11.21(chr7:61006478-62410831)x3
GRCh38/hg38 7q11.23(chr7:73040501-75255046)x3
GRCh38/hg38 7q21.13(chr7:88563550-90170632)x3
GRCh38/hg38 7q21.13(chr7:89030468-89447599)x1
GRCh38/hg38 8p23.1(chr8:7411297-8222398)x3
GRCh38/hg38 8q11.1(chr8:46031334-46662449)x1
GRCh38/hg38 8q11.1(chr8:46031334-46792065)x1
GRCh38/hg38 9p24.3(chr9:204193-295405)x3
GRCh38/hg38 9p24.3(chr9:204193-381489)x3
GRCh38/hg38 Xp22.31(chrX:6570680-8129470)x1
GRCh38/hg38 Yq11.222(chrY:17251756-19149935)x2
NCBI36/hg18 16p11.2-q24.3(chr16:31893599-33705883)x3

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