ClinVar Miner

Variants in gene ABCC2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
326 17 0 5 11 0 1 17

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 3 1 0 0
likely pathogenic 3 0 1 0 0
uncertain significance 1 1 0 10 1
likely benign 0 0 10 0 2
benign 0 0 1 2 0

All variants with conflicting interpretations #

Total variants: 17
Download table as spreadsheet
NM_000392.5(ABCC2):c.1007C>T (p.Thr336Met) rs149854486
NM_000392.5(ABCC2):c.1032-3C>T rs139800035
NM_000392.5(ABCC2):c.2034C>T (p.Ser678=) rs1554850241
NM_000392.5(ABCC2):c.2073C>A (p.Val691=) rs17222624
NM_000392.5(ABCC2):c.2273G>T (p.Gly758Val) rs786205465
NM_000392.5(ABCC2):c.2302C>T (p.Arg768Trp) rs56199535
NM_000392.5(ABCC2):c.2955G>A (p.Ala985=) rs139082536
NM_000392.5(ABCC2):c.306C>A (p.Thr102=) rs559908064
NM_000392.5(ABCC2):c.3107T>C (p.Ile1036Thr) rs45441199
NM_000392.5(ABCC2):c.3196C>T (p.Arg1066Ter) rs72558199
NM_000392.5(ABCC2):c.3258+1G>A rs762243203
NM_000392.5(ABCC2):c.3492C>T (p.Ser1164=) rs144192700
NM_000392.5(ABCC2):c.3576C>G (p.Thr1192=) rs146575217
NM_000392.5(ABCC2):c.3614+6G>C rs17222716
NM_000392.5(ABCC2):c.3648C>A (p.Asn1216Lys) rs144967259
NM_000392.5(ABCC2):c.842G>A (p.Ser281Asn) rs56131651
NM_000392.5(ABCC2):c.998A>G (p.Asp333Gly) rs17222674

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