Variants in gene ACADVL with conflicting interpretations "uncertain significance" and "likely pathogenic"

Submission 1 (uncertain significance) minimum review status:		Submission 1 (uncertain significance) method:
Submission 2 (likely pathogenic) minimum review status:		Submission 2 (likely pathogenic) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 82

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HGVS	dbSNP	gnomAD frequency
NM_000018.4(ACADVL):c.1844G>A (p.Arg615Gln)	rs148584617	0.00244
NM_000018.4(ACADVL):c.1591C>T (p.Arg531Trp)	rs146379816	0.00039
NM_000018.4(ACADVL):c.1894C>T (p.Arg632Cys)	rs151254520	0.00038
NM_000018.4(ACADVL):c.1220G>C (p.Gly407Ala)	rs904631654	0.00011
NM_000018.4(ACADVL):c.1273G>A (p.Ala425Thr)	rs138834083	0.00009
NM_000018.4(ACADVL):c.947G>A (p.Arg316Gln)	rs147366714	0.00006
NM_000018.4(ACADVL):c.760G>A (p.Gly254Ser)	rs765423779	0.00005
NM_000018.4(ACADVL):c.1153C>T (p.Arg385Trp)	rs745832866	0.00004
NM_000018.4(ACADVL):c.1531C>T (p.Arg511Trp)	rs771025937	0.00004
NM_000018.4(ACADVL):c.1820G>C (p.Cys607Ser)	rs200117742	0.00004
NM_000018.4(ACADVL):c.866G>A (p.Gly289Glu)	rs778514103	0.00004
NM_000018.4(ACADVL):c.1076C>T (p.Ala359Val)	rs539029862	0.00003
NM_000018.4(ACADVL):c.1096C>T (p.Arg366Cys)	rs771874163	0.00003
NM_000018.4(ACADVL):c.1246G>T (p.Ala416Ser)	rs118204018	0.00003
NM_000018.4(ACADVL):c.1748C>G (p.Ser583Trp)	rs1085307648	0.00003
NM_000018.4(ACADVL):c.1838G>A (p.Arg613Gln)	rs534647044	0.00003
NM_000018.4(ACADVL):c.521T>C (p.Val174Ala)	rs372684079	0.00003
NM_000018.4(ACADVL):c.1077G>A (p.Ala359=)	rs779458466	0.00002
NM_000018.4(ACADVL):c.1154G>A (p.Arg385Gln)	rs772014118	0.00002
NM_000018.4(ACADVL):c.485G>A (p.Arg162His)	rs754756970	0.00002
NM_000018.4(ACADVL):c.709T>C (p.Cys237Arg)	rs1189763523	0.00002
NM_000018.4(ACADVL):c.1001T>G (p.Met334Arg)	rs398123079	0.00001
NM_000018.4(ACADVL):c.1045G>A (p.Ala349Thr)	rs1567565733	0.00001
NM_000018.4(ACADVL):c.1127T>C (p.Phe376Ser)	rs758928307	0.00001
NM_000018.4(ACADVL):c.1146G>C (p.Lys382Asn)	rs1057523504	0.00001
NM_000018.4(ACADVL):c.1183-15A>G	rs765390290	0.00001
NM_000018.4(ACADVL):c.1198G>A (p.Val400Met)	rs149116708	0.00001
NM_000018.4(ACADVL):c.1217A>C (p.Gln406Pro)	rs1384021857	0.00001
NM_000018.4(ACADVL):c.1269G>A (p.Ser423=)	rs765356942	0.00001
NM_000018.4(ACADVL):c.1349G>A (p.Arg450His)	rs118204016	0.00001
NM_000018.4(ACADVL):c.1375C>T (p.Arg459Trp)	rs766742117	0.00001
NM_000018.4(ACADVL):c.1388G>A (p.Gly463Glu)	rs200366828	0.00001
NM_000018.4(ACADVL):c.1748C>T (p.Ser583Leu)	rs1085307648	0.00001
NM_000018.4(ACADVL):c.227G>A (p.Gly76Glu)	rs750043368	0.00001
NM_000018.4(ACADVL):c.374T>C (p.Leu125Pro)	rs1416443472	0.00001
NM_000018.4(ACADVL):c.428G>A (p.Gly143Asp)	rs1458941582	0.00001
NM_000018.4(ACADVL):c.538G>A (p.Ala180Thr)	rs727503791	0.00001
NM_000018.4(ACADVL):c.577G>C (p.Gly193Arg)	rs763630981	0.00001
NM_000018.4(ACADVL):c.622G>A (p.Gly208Arg)	rs748329498	0.00001
NM_000018.4(ACADVL):c.661A>G (p.Ser221Gly)	rs767063791	0.00001
NM_000018.4(ACADVL):c.751A>G (p.Ser251Gly)	rs749159573	0.00001
NM_000018.4(ACADVL):c.853G>C (p.Glu285Gln)	rs202216257	0.00001
NM_000018.4(ACADVL):c.881G>A (p.Gly294Glu)	rs200573371	0.00001
NM_000018.4(ACADVL):c.899T>G (p.Met300Arg)	rs142765230	0.00001
NM_000018.4(ACADVL):c.1019G>T (p.Gly340Val)	rs934797393
NM_000018.4(ACADVL):c.1055T>C (p.Met352Thr)
NM_000018.4(ACADVL):c.1062CAT[1] (p.Ile356del)	rs754325237
NM_000018.4(ACADVL):c.1072A>G (p.Lys358Glu)
NM_000018.4(ACADVL):c.1081G>A (p.Asp361Asn)	rs1331739604
NM_000018.4(ACADVL):c.1103A>C (p.Gln368Pro)	rs776063244
NM_000018.4(ACADVL):c.1276G>A (p.Ala426Thr)	rs1419478766
NM_000018.4(ACADVL):c.1309A>G (p.Met437Val)	rs2071345754
NM_000018.4(ACADVL):c.1321G>A (p.Gly441Ser)	rs2071346777
NM_000018.4(ACADVL):c.1328T>G (p.Met443Arg)	rs886043236
NM_000018.4(ACADVL):c.1376G>C (p.Arg459Pro)	rs751995154
NM_000018.4(ACADVL):c.1384G>A (p.Glu462Lys)	rs2071355499
NM_000018.4(ACADVL):c.1613G>C (p.Arg538Pro)	rs201350598
NM_000018.4(ACADVL):c.1616C>A (p.Ala539Asp)	rs781613690
NM_000018.4(ACADVL):c.1678+3_1678+6del	rs759135941
NM_000018.4(ACADVL):c.1808del (p.Cys603fs)	rs2142990894
NM_000018.4(ACADVL):c.1882del (p.Gln628fs)	rs1597541142
NM_000018.4(ACADVL):c.1923G>C (p.Leu641Phe)	rs1452402269
NM_000018.4(ACADVL):c.215C>T (p.Ser72Phe)	rs1161495077
NM_000018.4(ACADVL):c.260T>C (p.Val87Ala)	rs796051907
NM_000018.4(ACADVL):c.272C>A (p.Pro91Gln)	rs2071160066
NM_000018.4(ACADVL):c.277G>A (p.Val93Met)
NM_000018.4(ACADVL):c.425T>C (p.Phe142Ser)	rs398123088
NM_000018.4(ACADVL):c.430C>G (p.Leu144Val)
NM_000018.4(ACADVL):c.436G>C (p.Val146Leu)	rs398123089
NM_000018.4(ACADVL):c.481G>A (p.Ala161Thr)	rs375284481
NM_000018.4(ACADVL):c.507_527del (p.Met169_Gly175del)	rs796051920
NM_000018.4(ACADVL):c.533T>C (p.Leu178Pro)	rs1131691808
NM_000018.4(ACADVL):c.535G>T (p.Gly179Trp)	rs796051909
NM_000018.4(ACADVL):c.605T>A (p.Leu202His)	rs398123090
NM_000018.4(ACADVL):c.619T>C (p.Ser207Pro)	rs768975918
NM_000018.4(ACADVL):c.638C>T (p.Ala213Val)	rs2071252145
NM_000018.4(ACADVL):c.640T>G (p.Phe214Val)	rs1192969297
NM_000018.4(ACADVL):c.689C>T (p.Thr230Ile)	rs1241935771
NM_000018.4(ACADVL):c.722A>G (p.Tyr241Cys)	rs575789958
NM_000018.4(ACADVL):c.739A>G (p.Lys247Glu)	rs387906253
NM_000018.4(ACADVL):c.829_831del (p.Glu277del)	rs796051913
NM_000018.4(ACADVL):c.869G>A (p.Gly290Asp)

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