ClinVar Miner

Variants in gene ADAMTS2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
200 35 0 27 22 0 0 40

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 0 0 0
likely pathogenic 1 0 0 0 0
uncertain significance 0 0 0 18 13
likely benign 0 0 18 0 26
benign 0 0 13 26 0

All variants with conflicting interpretations #

Total variants: 40
Download table as spreadsheet
HGVS dbSNP
NM_014244.4(ADAMTS2):c.1122C>T (p.Ser374=) rs145109914
NM_014244.4(ADAMTS2):c.1164G>A (p.Pro388=) rs141348218
NM_014244.4(ADAMTS2):c.1281C>T (p.Asp427=) rs34424371
NM_014244.4(ADAMTS2):c.1308G>A (p.Ala436=) rs41285549
NM_014244.4(ADAMTS2):c.1431G>A (p.Ala477=) rs147259971
NM_014244.4(ADAMTS2):c.1458C>T (p.Tyr486=) rs61757478
NM_014244.4(ADAMTS2):c.1488C>T (p.Phe496=) rs147438064
NM_014244.4(ADAMTS2):c.1629+9G>A rs115550684
NM_014244.4(ADAMTS2):c.1644A>G (p.Gly548=) rs61731454
NM_014244.4(ADAMTS2):c.1695C>T (p.Gly565=) rs116708837
NM_014244.4(ADAMTS2):c.1803G>A (p.Ser601=) rs76754323
NM_014244.4(ADAMTS2):c.1908C>T (p.His636=) rs1862211
NM_014244.4(ADAMTS2):c.1993G>A (p.Gly665Arg) rs35372714
NM_014244.4(ADAMTS2):c.2073C>T (p.Arg691=) rs149391669
NM_014244.4(ADAMTS2):c.220G>A (p.Val74Met) rs2271211
NM_014244.4(ADAMTS2):c.2291-8A>G rs140401199
NM_014244.4(ADAMTS2):c.2292C>T (p.Ala764=) rs188566209
NM_014244.4(ADAMTS2):c.2384G>A (p.Trp795Ter) rs137853147
NM_014244.4(ADAMTS2):c.2439C>T (p.His813=) rs141661592
NM_014244.4(ADAMTS2):c.2480G>A (p.Arg827Gln) rs35445112
NM_014244.4(ADAMTS2):c.2730A>G (p.Pro910=) rs6869261
NM_014244.4(ADAMTS2):c.2751-4G>A rs112155474
NM_014244.4(ADAMTS2):c.2795G>A (p.Arg932Gln) rs140022033
NM_014244.4(ADAMTS2):c.2817C>T (p.Ser939=) rs201215425
NM_014244.4(ADAMTS2):c.3014C>T (p.Ala1005Val) rs79330641
NM_014244.4(ADAMTS2):c.3279T>C (p.Cys1093=) rs73806887
NM_014244.4(ADAMTS2):c.3342C>T (p.Asn1114=) rs79606317
NM_014244.4(ADAMTS2):c.3480C>A (p.Ala1160=) rs34437036
NM_014244.4(ADAMTS2):c.3506G>T (p.Gly1169Val) rs117187367
NM_014244.4(ADAMTS2):c.596C>T (p.Ala199Val) rs76704342
NM_014244.4(ADAMTS2):c.68T>C (p.Leu23Pro) rs565885690
NM_014244.4(ADAMTS2):c.68_70delTGC (p.Leu23del) rs568040559
NM_014244.4(ADAMTS2):c.701A>G (p.Asp234Gly) rs59567206
NM_014244.4(ADAMTS2):c.722G>A (p.Arg241His) rs11750821
NM_014244.4(ADAMTS2):c.748G>A (p.Ala250Thr) rs143764421
NM_014244.4(ADAMTS2):c.764G>A (p.Arg255Gln) rs117222015
NM_014244.4(ADAMTS2):c.80_88dupTCCTGCCGC (p.Pro29_Pro30insLeuLeuPro) rs775509290
NM_014244.4(ADAMTS2):c.858C>T (p.His286=) rs66565583
NM_014244.4(ADAMTS2):c.936C>T (p.Asn312=) rs35462609
NM_021599.3(ADAMTS2):c.80_100dup (p.Pro33_Pro34insLeuLeuProProProProPro) rs1064794627

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