Variants in gene ALS2 with conflicting interpretations "likely benign" and "uncertain significance"

Submission 1 (likely benign) minimum review status:		Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status:		Submission 2 (uncertain significance) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 14

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HGVS	dbSNP	gnomAD frequency
NM_020919.4(ALS2):c.2241C>T (p.Tyr747=)	rs3219160	0.00208
NM_020919.4(ALS2):c.1816-8C>T	rs185911369	0.00165
NM_020919.4(ALS2):c.3741T>G (p.Gly1247=)	rs3219166	0.00112
NM_020919.4(ALS2):c.3046C>G (p.Pro1016Ala)	rs41308840	0.00099
NM_020919.4(ALS2):c.2479A>T (p.Thr827Ser)	rs202219507	0.00061
NM_020919.4(ALS2):c.4416G>A (p.Thr1472=)	rs200202953	0.00056
NM_020919.4(ALS2):c.1641G>A (p.Arg547=)	rs34122078	0.00038
NM_020919.4(ALS2):c.1627G>A (p.Asp543Asn)	rs201161419	0.00036
NM_020919.4(ALS2):c.1677A>G (p.Lys559=)	rs367640165	0.00026
NM_020919.4(ALS2):c.331G>A (p.Val111Ile)	rs61745503	0.00010
NM_020919.4(ALS2):c.886G>A (p.Ala296Thr)	rs765049503	0.00004
NM_020919.4(ALS2):c.1640+10A>G	rs755148474	0.00001
NM_020919.4(ALS2):c.2171-7G>A	rs376270303	0.00001
NM_020919.4(ALS2):c.2491_2499del (p.Glu831_Leu833del)	rs773628251

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