ClinVar Miner

Variants in gene combination ANK2, LOC126807137 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
217 24 0 17 25 0 1 42

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic uncertain significance likely benign benign
pathogenic 0 1 0 0
uncertain significance 1 0 25 0
likely benign 0 25 0 17
benign 0 0 17 0

All variants with conflicting interpretations #

Total variants: 42
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HGVS dbSNP gnomAD frequency
NM_001148.6(ANK2):c.7106T>C (p.Val2369Ala) rs28377576 0.12654
NM_001148.6(ANK2):c.7831T>C (p.Tyr2611His) rs35338364 0.00539
NM_001148.6(ANK2):c.7132G>A (p.Glu2378Lys) rs141191319 0.00222
NM_001148.6(ANK2):c.7902G>A (p.Val2634=) rs150878494 0.00138
NM_001148.6(ANK2):c.6906C>T (p.Thr2302=) rs139910215 0.00133
NM_001148.6(ANK2):c.7059A>G (p.Gln2353=) rs145782226 0.00124
NM_001148.6(ANK2):c.6912T>C (p.Thr2304=) rs190680846 0.00058
NM_001148.6(ANK2):c.7971C>T (p.Ser2657=) rs146085234 0.00051
NM_001148.6(ANK2):c.7267G>A (p.Ala2423Thr) rs3733616 0.00038
NM_001148.6(ANK2):c.7488A>G (p.Thr2496=) rs143161930 0.00031
NM_001148.6(ANK2):c.7707A>G (p.Ala2569=) rs144407821 0.00026
NM_001148.6(ANK2):c.7265G>A (p.Ser2422Asn) rs140341680 0.00019
NM_001148.6(ANK2):c.7148C>T (p.Pro2383Leu) rs35960628 0.00017
NM_001148.6(ANK2):c.7183A>C (p.Thr2395Pro) rs201693280 0.00017
NM_001148.6(ANK2):c.7251T>C (p.Asp2417=) rs201688836 0.00016
NM_001148.6(ANK2):c.6854T>C (p.Ile2285Thr) rs150684838 0.00014
NM_001148.6(ANK2):c.7436A>G (p.Lys2479Arg) rs201619005 0.00013
NM_001148.6(ANK2):c.7117A>G (p.Thr2373Ala) rs184514058 0.00012
NM_001148.6(ANK2):c.7868C>G (p.Ser2623Cys) rs116253689 0.00010
NM_001148.6(ANK2):c.7168A>C (p.Lys2390Gln) rs151218210 0.00009
NM_001148.6(ANK2):c.7131C>T (p.Asp2377=) rs553324580 0.00008
NM_001148.6(ANK2):c.7964C>T (p.Ser2655Leu) rs373153154 0.00007
NM_001148.6(ANK2):c.7412G>A (p.Ser2471Asn) rs375139170 0.00006
NM_001148.6(ANK2):c.7932G>A (p.Glu2644=) rs201645638 0.00006
NM_001148.6(ANK2):c.7320C>T (p.Ser2440=) rs190590036 0.00005
NM_001148.6(ANK2):c.6973G>C (p.Asp2325His) rs1298469624 0.00004
NM_001148.6(ANK2):c.7105G>T (p.Val2369Phe) rs758054052 0.00004
NM_001148.6(ANK2):c.7396C>T (p.Arg2466Cys) rs562115547 0.00004
NM_001148.6(ANK2):c.7136C>A (p.Thr2379Lys) rs753351853 0.00003
NM_001148.6(ANK2):c.6875G>A (p.Arg2292Gln) rs1350377647 0.00001
NM_001148.6(ANK2):c.7249G>C (p.Asp2417His) rs372545180 0.00001
NM_001148.6(ANK2):c.7532G>A (p.Arg2511Gln) rs142684331 0.00001
NM_001148.6(ANK2):c.7546A>G (p.Ser2516Gly) rs771826064 0.00001
NM_001148.6(ANK2):c.7943G>A (p.Gly2648Asp) rs563254150 0.00001
NM_001148.6(ANK2):c.7951G>C (p.Val2651Leu) rs777477439 0.00001
NM_001148.6(ANK2):c.7054_7059del (p.Gly2352_Gln2353del) rs774514148
NM_001148.6(ANK2):c.7084A>G (p.Lys2362Glu)
NM_001148.6(ANK2):c.7106T>G (p.Val2369Gly) rs28377576
NM_001148.6(ANK2):c.7531C>T (p.Arg2511Ter) rs2154024936
NM_001148.6(ANK2):c.7706_7707inv (p.Ala2569Val)
NM_001148.6(ANK2):c.7942G>C (p.Gly2648Arg) rs199828363
NM_001148.6(ANK2):c.7985C>T (p.Ser2662Phe) rs1564029811

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