ClinVar Miner

Variants in gene APOB with conflicting interpretations

See also:
Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
576 147 0 107 112 0 12 172

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 4 9 2 2
likely pathogenic 4 0 6 1 1
uncertain significance 9 6 0 105 60
likely benign 2 1 105 0 103
benign 2 1 60 103 0

All variants with conflicting interpretations #

Total variants: 172
Download table as spreadsheet
HGVS dbSNP
NM_000384.2(APOB):c.10061C>G (p.Ala3354Gly) rs61742331
NM_000384.2(APOB):c.10131G>A (p.Leu3377=) rs1799812
NM_000384.2(APOB):c.10182G>T (p.Lys3394Asn) rs1382988295
NM_000384.2(APOB):c.10294C>G (p.Gln3432Glu) rs1042023
NM_000384.2(APOB):c.10520G>C (p.Arg3507Pro) rs201156840
NM_000384.2(APOB):c.10575C>T (p.Ser3525=) rs142573551
NM_000384.2(APOB):c.10579C>T (p.Arg3527Trp) rs144467873
NM_000384.2(APOB):c.10580G>A (p.Arg3527Gln) rs5742904
NM_000384.2(APOB):c.10672C>T (p.Arg3558Cys) rs12713559
NM_000384.2(APOB):c.10700C>T (p.Thr3567Met) rs368278927
NM_000384.2(APOB):c.10701G>A (p.Thr3567=) rs12713558
NM_000384.2(APOB):c.10708C>T (p.His3570Tyr) rs201736972
NM_000384.2(APOB):c.10737C>T (p.Thr3579=) rs12713554
NM_000384.2(APOB):c.10740C>T (p.Asn3580=) rs150312765
NM_000384.2(APOB):c.10780T>C (p.Trp3594Arg) rs61744288
NM_000384.2(APOB):c.10913G>A (p.Arg3638Gln) rs1801701
NM_000384.2(APOB):c.11257T>C (p.Phe3753Leu) rs61741974
NM_000384.2(APOB):c.11354C>T (p.Thr3785Ile) rs143710616
NM_000384.2(APOB):c.11356C>T (p.Leu3786Phe) rs571485213
NM_000384.2(APOB):c.11362G>A (p.Glu3788Lys) rs13306191
NM_000384.2(APOB):c.11401T>A (p.Ser3801Thr) rs12713540
NM_000384.2(APOB):c.11477C>T (p.Thr3826Met) rs61744153
NM_000384.2(APOB):c.11568C>T (p.Ile3856=) rs542175556
NM_000384.2(APOB):c.11761G>A (p.Val3921Ile) rs72654409
NM_000384.2(APOB):c.11789-8C>T rs201274370
NM_000384.2(APOB):c.11808C>T (p.Ile3936=) rs12720852
NM_000384.2(APOB):c.11819C>T (p.Thr3940Met) rs72654416
NM_000384.2(APOB):c.11833A>G (p.Thr3945Ala) rs1801698
NM_000384.2(APOB):c.11854C>T (p.Arg3952Cys) rs535121944
NM_000384.2(APOB):c.11904-15T>A rs370325726
NM_000384.2(APOB):c.11904-7C>T rs12720851
NM_000384.2(APOB):c.11911G>A (p.Glu3971Lys) rs373477107
NM_000384.2(APOB):c.1199G>A (p.Arg400His) rs530171166
NM_000384.2(APOB):c.12016G>A (p.Val4006Ile) rs183117027
NM_000384.2(APOB):c.12024C>T (p.Thr4008=) rs145269223
NM_000384.2(APOB):c.12088-13delT rs751121092
NM_000384.2(APOB):c.12088-13dupT rs751121092
NM_000384.2(APOB):c.12088-14T>C rs182329513
NM_000384.2(APOB):c.1223T>C (p.Ile408Thr) rs12714225
NM_000384.2(APOB):c.12252T>C (p.Tyr4084=) rs138157751
NM_000384.2(APOB):c.12310C>A (p.Leu4104Met) rs199668351
NM_000384.2(APOB):c.12318A>G (p.Arg4106=) rs375795401
NM_000384.2(APOB):c.12382G>A (p.Val4128Met) rs1801703
NM_000384.2(APOB):c.12444C>A (p.Ala4148=) rs757789853
NM_000384.2(APOB):c.12541G>A (p.Glu4181Lys) rs1042031
NM_000384.2(APOB):c.12697T>A (p.Ser4233Thr) rs61743299
NM_000384.2(APOB):c.12699G>A (p.Ser4233=) rs56675344
NM_000384.2(APOB):c.12766G>A (p.Glu4256Lys) rs61743313
NM_000384.2(APOB):c.12794T>C (p.Val4265Ala) rs61743502
NM_000384.2(APOB):c.12803T>C (p.Met4268Thr) rs72654422
NM_000384.2(APOB):c.12809G>C (p.Arg4270Thr) rs1801702
NM_000384.2(APOB):c.1280G>A (p.Arg427Gln) rs755407886
NM_000384.2(APOB):c.12903C>T (p.Asp4301=) rs200145506
NM_000384.2(APOB):c.12940A>G (p.Ile4314Val) rs72654423
NM_000384.2(APOB):c.13013G>A (p.Ser4338Asn) rs1042034
NM_000384.2(APOB):c.13028_13029delAT (p.Tyr4343Cysfs) rs760832994
NM_000384.2(APOB):c.13102C>G (p.Gln4368Glu) rs72654424
NM_000384.2(APOB):c.1310G>A (p.Arg437His) rs142114415
NM_000384.2(APOB):c.13154G>A (p.Arg4385His) rs533755016
NM_000384.2(APOB):c.13160A>T (p.Glu4387Val) rs150412734
NM_000384.2(APOB):c.13302C>T (p.Ser4434=) rs144040999
NM_000384.2(APOB):c.13441G>A (p.Ala4481Thr) rs1801695
NM_000384.2(APOB):c.13449G>A (p.Ala4483=) rs138421941
NM_000384.2(APOB):c.13451C>T (p.Thr4484Met) rs12713450
NM_000384.2(APOB):c.13480_13482delCAG (p.Gln4494del) rs562574661
NM_000384.2(APOB):c.1353-12C>T rs76202659
NM_000384.2(APOB):c.1470+15T>C rs185550846
NM_000384.2(APOB):c.1594C>T (p.Arg532Trp) rs13306194
NM_000384.2(APOB):c.1648G>C (p.Asp550His) rs145862664
NM_000384.2(APOB):c.1661C>T (p.Pro554Leu) rs12714214
NM_000384.2(APOB):c.1785C>G (p.Ser595=) rs139864087
NM_000384.2(APOB):c.1853C>T (p.Ala618Val) rs679899
NM_000384.2(APOB):c.2068-4T>A rs41291161
NM_000384.2(APOB):c.2188G>A (p.Val730Ile) rs12691202
NM_000384.2(APOB):c.2222C>A (p.Thr741Asn) rs12714192
NM_000384.2(APOB):c.2244+3G>A rs12714189
NM_000384.2(APOB):c.2585T>C (p.Val862Ala) rs145142090
NM_000384.2(APOB):c.2604+15G>C rs72653066
NM_000384.2(APOB):c.2630C>T (p.Pro877Leu) rs12714097
NM_000384.2(APOB):c.2706C>T (p.Asn902=) rs1801700
NM_000384.2(APOB):c.2817-19T>G rs72653069
NM_000384.2(APOB):c.2823A>G (p.Thr941=) rs200868559
NM_000384.2(APOB):c.2853G>A (p.Glu951=) rs151193347
NM_000384.2(APOB):c.285C>A (p.Ser95Arg) rs143613534
NM_000384.2(APOB):c.2863C>T (p.Pro955Ser) rs13306206
NM_000384.2(APOB):c.288G>T (p.Gln96His) rs186544754
NM_000384.2(APOB):c.293C>T (p.Thr98Ile) rs1367117
NM_000384.2(APOB):c.2968G>A (p.Ala990Thr) rs139434026
NM_000384.2(APOB):c.2981C>T (p.Pro994Leu) rs41288783
NM_000384.2(APOB):c.3034G>A (p.Glu1012Lys) rs575505383
NM_000384.2(APOB):c.307T>C (p.Tyr103His) rs9282603
NM_000384.2(APOB):c.3122-6G>A rs72653071
NM_000384.2(APOB):c.3178T>C (p.Leu1060=) rs72653073
NM_000384.2(APOB):c.3337G>C (p.Asp1113His) rs12713844
NM_000384.2(APOB):c.3383G>A (p.Arg1128His) rs12713843
NM_000384.2(APOB):c.3426G>A (p.Ser1142=) rs142448733
NM_000384.2(APOB):c.3427C>T (p.Pro1143Ser) rs72653077
NM_000384.2(APOB):c.3471T>C (p.Tyr1157=) rs201128198
NM_000384.2(APOB):c.3491G>A (p.Arg1164Lys) rs759845943
NM_000384.2(APOB):c.3491G>C (p.Arg1164Thr) rs759845943
NM_000384.2(APOB):c.3509-10G>A rs12720770
NM_000384.2(APOB):c.3509-11C>T rs200768300
NM_000384.2(APOB):c.3634C>A (p.Leu1212Met) rs61736761
NM_000384.2(APOB):c.3712C>A (p.Leu1238Ile) rs72653078
NM_000384.2(APOB):c.3740A>G (p.Tyr1247Cys) rs61741164
NM_000384.2(APOB):c.3843C>T (p.Ser1281=) rs72653079
NM_000384.2(APOB):c.400G>T (p.Ala134Ser) rs368321279
NM_000384.2(APOB):c.403A>G (p.Ile135Val) rs769296548
NM_000384.2(APOB):c.4163G>A (p.Arg1388His) rs13306187
NM_000384.2(APOB):c.4178C>T (p.Ala1393Val) rs143282164
NM_000384.2(APOB):c.433C>T (p.Pro145Ser) rs6752026
NM_000384.2(APOB):c.4365C>T (p.Phe1455=) rs12720847
NM_000384.2(APOB):c.4449A>G (p.Glu1483=) rs151018874
NM_000384.2(APOB):c.4656T>C (p.Ser1552=) rs761580028
NM_000384.2(APOB):c.4663A>G (p.Ile1555Val) rs141225768
NM_000384.2(APOB):c.4825T>C (p.Leu1609=) rs72653083
NM_000384.2(APOB):c.4929G>A (p.Ala1643=) rs200623857
NM_000384.2(APOB):c.499C>T (p.Pro167Ser) rs139842930
NM_000384.2(APOB):c.5066G>A (p.Arg1689His) rs151009667
NM_000384.2(APOB):c.5322C>T (p.Tyr1774=) rs13306188
NM_000384.2(APOB):c.538-9C>T rs1800478
NM_000384.2(APOB):c.5690G>A (p.Arg1897His) rs199510126
NM_000384.2(APOB):c.5741A>G (p.Asn1914Ser) rs1801699
NM_000384.2(APOB):c.5763A>G (p.Gly1921=) rs141022509
NM_000384.2(APOB):c.5768A>G (p.His1923Arg) rs533617
NM_000384.2(APOB):c.581C>T (p.Thr194Met) rs13306198
NM_000384.2(APOB):c.5913G>A (p.Leu1971=) rs374251542
NM_000384.2(APOB):c.606A>T (p.Glu202Asp) rs61746672
NM_000384.2(APOB):c.607A>G (p.Ile203Val) rs72653059
NM_000384.2(APOB):c.6136G>A (p.Val2046Ile) rs72653084
NM_000384.2(APOB):c.6261C>A (p.Thr2087=) rs61744855
NM_000384.2(APOB):c.6639_6641delTGA (p.Asp2213del) rs541497967
NM_000384.2(APOB):c.6656G>A (p.Arg2219His) rs200106845
NM_000384.2(APOB):c.6895G>C (p.Asp2299His) rs12713681
NM_000384.2(APOB):c.6936C>T (p.Asp2312=) rs1041968
NM_000384.2(APOB):c.6937G>A (p.Val2313Ile) rs584542
NM_000384.2(APOB):c.7242A>C (p.Glu2414Asp) rs72653091
NM_000384.2(APOB):c.7283A>G (p.Lys2428Arg) rs1369533953
NM_000384.2(APOB):c.7285T>A (p.Ser2429Thr) rs72653092
NM_000384.2(APOB):c.7367C>A (p.Ala2456Asp) rs12713675
NM_000384.2(APOB):c.751G>A (p.Ala251Thr) rs61741625
NM_000384.2(APOB):c.7545C>T (p.Thr2515=) rs693
NM_000384.2(APOB):c.7612C>T (p.Leu2538=) rs72653093
NM_000384.2(APOB):c.7615G>A (p.Val2539Ile) rs148170480
NM_000384.2(APOB):c.7619G>T (p.Gly2540Val) rs571626569
NM_000384.2(APOB):c.7696G>A (p.Glu2566Lys) rs1801696
NM_000384.2(APOB):c.7853T>C (p.Ile2618Thr) rs531273434
NM_000384.2(APOB):c.7989T>C (p.Ile2663=) rs199642915
NM_000384.2(APOB):c.8148C>T (p.Ile2716=) rs6413458
NM_000384.2(APOB):c.8216C>T (p.Pro2739Leu) rs676210
NM_000384.2(APOB):c.8295A>G (p.Gln2765=) rs767506952
NM_000384.2(APOB):c.8353A>C (p.Asn2785His) rs2163204
NM_000384.2(APOB):c.8462C>T (p.Pro2821Leu) rs72653095
NM_000384.2(APOB):c.8469T>C (p.Ala2823=) rs531216195
NM_000384.2(APOB):c.8720G>A (p.Arg2907His) rs751437976
NM_000384.2(APOB):c.8877G>A (p.Leu2959=) rs765899256
NM_000384.2(APOB):c.8889C>T (p.Ile2963=) rs72653097
NM_000384.2(APOB):c.8912A>C (p.Asn2971Thr) rs72653098
NM_000384.2(APOB):c.9004C>T (p.Leu3002=) rs12713600
NM_000384.2(APOB):c.905-15C>G rs72653061
NM_000384.2(APOB):c.905-16A>C rs12720810
NM_000384.2(APOB):c.9105T>C (p.Asn3035=) rs147510760
NM_000384.2(APOB):c.9140C>G (p.Thr3047Arg) rs61742323
NM_000384.2(APOB):c.9175C>T (p.Arg3059Cys) rs146377316
NM_000384.2(APOB):c.9294C>T (p.Tyr3098=) rs145777339
NM_000384.2(APOB):c.9477G>A (p.Lys3159=) rs13306196
NM_000384.2(APOB):c.9639C>A (p.Asn3213Lys) rs574725520
NM_000384.2(APOB):c.9811G>A (p.Gly3271Ser) rs142422341
NM_000384.2(APOB):c.9835A>G (p.Ser3279Gly) rs12720854
NM_000384.2(APOB):c.9855C>T (p.Ile3285=) rs72654403
NM_000384.2(APOB):c.9880T>C (p.Ser3294Pro) rs12720855
NM_000384.2(APOB):c.9883T>C (p.Tyr3295His) rs186299244

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.