ClinVar Miner

Variants in gene AXIN2 with conflicting interpretations

See also:
Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic) 		Variants with a confidence conflict
(e.g. benign vs likely benign) 		Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects) 		Variants with a clinically significant conflict
(e.g. benign vs pathogenic) 		Variants with any conflict
3172 222 0 70 69 0 4 124

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 0 1 0 0
likely pathogenic 0 0 3 1 1
uncertain significance 1 3 0 67 14
likely benign 0 1 67 0 70
benign 0 1 14 70 0

All variants with conflicting interpretations #

Total variants: 124
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_004655.4(AXIN2):c.1615G>A (p.Val539Met) rs9913621 0.01361
NM_004655.4(AXIN2):c.1573C>G (p.Pro525Ala) rs73346297 0.00930
NM_004655.4(AXIN2):c.2282C>A (p.Ala761Asp) rs79732150 0.00649
NM_004655.4(AXIN2):c.1410C>T (p.His470=) rs149483825 0.00394
NM_004655.4(AXIN2):c.1530G>A (p.Thr510=) rs141014640 0.00299
NM_004655.4(AXIN2):c.2272G>A (p.Ala758Thr) rs145007501 0.00179
NM_004655.4(AXIN2):c.1070G>A (p.Arg357His) rs8081536 0.00172
NM_004655.4(AXIN2):c.1713-18G>A rs147664289 0.00169
NM_004655.4(AXIN2):c.1200+19T>C rs116931989 0.00165
NM_004655.4(AXIN2):c.1200+18T>G rs117258157 0.00163
NM_004655.4(AXIN2):c.2439C>T (p.Ala813=) rs149533605 0.00157
NM_004655.4(AXIN2):c.1807G>C (p.Ala603Pro) rs145353986 0.00128
NM_004655.4(AXIN2):c.1952C>T (p.Ser651Leu) rs74006838 0.00128
NM_004655.4(AXIN2):c.2428G>A (p.Asp810Asn) rs140344858 0.00123
NM_004655.4(AXIN2):c.2051C>T (p.Ala684Val) rs138287857 0.00112
NM_004655.4(AXIN2):c.1532C>T (p.Thr511Met) rs200883019 0.00109
NM_004655.4(AXIN2):c.1101C>T (p.Pro367=) rs141697521 0.00094
NM_004655.4(AXIN2):c.1985T>C (p.Leu662Pro) rs142476324 0.00084
NM_004655.4(AXIN2):c.270C>T (p.Asp90=) rs141655687 0.00076
NM_004655.4(AXIN2):c.1168A>G (p.Ser390Gly) rs139871607 0.00075
NM_004655.4(AXIN2):c.1545C>T (p.His515=) rs139316692 0.00070
NM_004655.4(AXIN2):c.1250C>T (p.Ala417Val) rs201460658 0.00064
NM_004655.4(AXIN2):c.2285G>A (p.Ser762Asn) rs117688560 0.00064
NM_004655.4(AXIN2):c.2052G>A (p.Ala684=) rs200573256 0.00046
NM_004655.4(AXIN2):c.733C>T (p.Pro245Ser) rs62640028 0.00043
NM_004655.4(AXIN2):c.1685C>T (p.Pro562Leu) rs149764887 0.00031
NM_004655.4(AXIN2):c.2213C>T (p.Ser738Phe) rs139209450 0.00031
NM_004655.4(AXIN2):c.1059+8C>T rs367595502 0.00025
NM_004655.4(AXIN2):c.815+7C>T rs142103235 0.00025
NM_004655.4(AXIN2):c.-33A>C rs190687283 0.00024
NM_004655.4(AXIN2):c.1637G>T (p.Gly546Val) rs145717795 0.00024
NM_004655.4(AXIN2):c.879A>G (p.Pro293=) rs374479599 0.00024
NM_004655.4(AXIN2):c.1368C>T (p.Gly456=) rs372841853 0.00021
NM_004655.4(AXIN2):c.203G>A (p.Arg68Gln) rs138056036 0.00020
NM_004655.4(AXIN2):c.1829G>A (p.Arg610Gln) rs376248072 0.00018
NM_004655.4(AXIN2):c.1242G>A (p.Arg414=) rs200325634 0.00016
NM_004655.4(AXIN2):c.780T>C (p.Ser260=) rs147681058 0.00016
NM_004655.4(AXIN2):c.344A>G (p.Asn115Ser) rs370257532 0.00015
NM_004655.4(AXIN2):c.1176G>A (p.Glu392=) rs376052287 0.00014
NM_004655.4(AXIN2):c.1305G>A (p.Pro435=) rs369221405 0.00014
NM_004655.4(AXIN2):c.1327C>T (p.Leu443=) rs371691797 0.00013
NM_004655.4(AXIN2):c.144C>T (p.Pro48=) rs144099816 0.00013
NM_004655.4(AXIN2):c.1633G>T (p.Gly545Trp) rs148951121 0.00013
NM_004655.4(AXIN2):c.1948C>T (p.Arg650Cys) rs148419444 0.00013
NM_004655.4(AXIN2):c.435C>A (p.Val145=) rs111470596 0.00013
NM_004655.4(AXIN2):c.1882C>T (p.Arg628Trp) rs200201811 0.00011
NM_004655.4(AXIN2):c.2433G>A (p.Glu811=) rs147134295 0.00011
NM_004655.4(AXIN2):c.1181G>A (p.Arg394His) rs200899695 0.00010
NM_004655.4(AXIN2):c.1376G>A (p.Arg459His) rs368525111 0.00010
NM_004655.4(AXIN2):c.1907+17G>A rs201487132 0.00010
NM_004655.4(AXIN2):c.2142-20C>T rs764171738 0.00010
NM_004655.4(AXIN2):c.2406-8C>G rs143905290 0.00009
NM_004655.4(AXIN2):c.1623C>T (p.Cys541=) rs199931425 0.00008
NM_004655.4(AXIN2):c.2239C>T (p.His747Tyr) rs143571197 0.00008
NM_004655.4(AXIN2):c.475G>T (p.Asp159Tyr) rs753036084 0.00008
NM_004655.4(AXIN2):c.738C>T (p.Thr246=) rs201191083 0.00008
NM_004655.4(AXIN2):c.1201-7C>T rs760667639 0.00006
NM_004655.4(AXIN2):c.1267C>T (p.Leu423Phe) rs376630432 0.00006
NM_004655.4(AXIN2):c.1598C>T (p.Ala533Val) rs147716924 0.00006
NM_004655.4(AXIN2):c.2237+3G>A rs376584101 0.00006
NM_004655.4(AXIN2):c.623C>T (p.Ala208Val) rs201531372 0.00006
NM_004655.4(AXIN2):c.2140C>T (p.Arg714Trp) rs148765149 0.00005
NM_004655.4(AXIN2):c.1092C>T (p.Pro364=) rs765518896 0.00004
NM_004655.4(AXIN2):c.1222G>A (p.Glu408Lys) rs749846538 0.00004
NM_004655.4(AXIN2):c.1553A>G (p.Tyr518Cys) rs368289818 0.00004
NM_004655.4(AXIN2):c.2004G>A (p.Gly668=) rs144092307 0.00004
NM_004655.4(AXIN2):c.2083G>T (p.Ala695Ser) rs140510381 0.00004
NM_004655.4(AXIN2):c.2216A>G (p.Asn739Ser) rs547630327 0.00004
NM_004655.4(AXIN2):c.2379G>A (p.Glu793=) rs1367633896 0.00004
NM_004655.4(AXIN2):c.1485C>T (p.Gly495=) rs770556906 0.00003
NM_004655.4(AXIN2):c.1635G>A (p.Gly545=) rs778710067 0.00003
NM_004655.4(AXIN2):c.2184C>T (p.Ala728=) rs146547133 0.00003
NM_004655.4(AXIN2):c.2196G>A (p.Thr732=) rs878854725 0.00003
NM_004655.4(AXIN2):c.2405+4A>G rs377423720 0.00003
NM_004655.4(AXIN2):c.645C>T (p.Leu215=) rs767834824 0.00003
NM_004655.4(AXIN2):c.135C>T (p.Val45=) rs376726966 0.00002
NM_004655.4(AXIN2):c.1887G>A (p.Gln629=) rs140163819 0.00002
NM_004655.4(AXIN2):c.1976G>A (p.Arg659Gln) rs730881400 0.00002
NM_004655.4(AXIN2):c.522G>T (p.Ala174=) rs780914406 0.00002
NM_004655.4(AXIN2):c.897C>T (p.Asp299=) rs748143308 0.00002
NM_004655.4(AXIN2):c.1200+8G>A rs776372607 0.00001
NM_004655.4(AXIN2):c.1251G>T (p.Ala417=) rs557397475 0.00001
NM_004655.4(AXIN2):c.1284C>A (p.Ser428=) rs750126379 0.00001
NM_004655.4(AXIN2):c.13A>G (p.Met5Val) rs148691166 0.00001
NM_004655.4(AXIN2):c.1494C>T (p.Pro498=) rs1353761854 0.00001
NM_004655.4(AXIN2):c.1510G>C (p.Gly504Arg) rs757512425 0.00001
NM_004655.4(AXIN2):c.1531A>T (p.Thr511Ser) rs376936740 0.00001
NM_004655.4(AXIN2):c.1713-2A>G rs766170422 0.00001
NM_004655.4(AXIN2):c.1713C>T (p.Gly571=) rs761978806 0.00001
NM_004655.4(AXIN2):c.1780G>A (p.Ala594Thr) rs876660965 0.00001
NM_004655.4(AXIN2):c.1908-2A>G rs978837790 0.00001
NM_004655.4(AXIN2):c.1962C>A (p.Gly654=) rs377642903 0.00001
NM_004655.4(AXIN2):c.2100C>T (p.Ala700=) rs1057522521 0.00001
NM_004655.4(AXIN2):c.21G>A (p.Val7=) rs1467193033 0.00001
NM_004655.4(AXIN2):c.2405+7G>A rs373593841 0.00001
NM_004655.4(AXIN2):c.2487G>A (p.Pro829=) rs768793839 0.00001
NM_004655.4(AXIN2):c.2499C>A (p.Gly833=) rs772461187 0.00001
NM_004655.4(AXIN2):c.33G>A (p.Pro11=) rs768626471 0.00001
NM_004655.4(AXIN2):c.414C>T (p.Tyr138=) rs878854730 0.00001
NM_004655.4(AXIN2):c.558C>T (p.Ala186=) rs1598119456 0.00001
NM_004655.4(AXIN2):c.598G>A (p.Val200Met) rs752081909 0.00001
NM_004655.4(AXIN2):c.652C>G (p.Leu218Val) rs766935285 0.00001
NM_004655.4(AXIN2):c.721T>G (p.Cys241Gly) rs370549410 0.00001
NM_004655.4(AXIN2):c.815+4A>G rs565020131 0.00001
NM_004655.4(AXIN2):c.-12_8del (p.Met1fs) rs768265778
NM_004655.4(AXIN2):c.1235A>G (p.Asn412Ser) rs115931022
NM_004655.4(AXIN2):c.1338C>A (p.Val446=) rs369864600
NM_004655.4(AXIN2):c.1347C>T (p.Thr449=) rs762279806
NM_004655.4(AXIN2):c.1380T>C (p.Tyr460=) rs566313620
NM_004655.4(AXIN2):c.1404CCA[5] (p.His474del) rs570443161
NM_004655.4(AXIN2):c.1404CCA[7] (p.His474dup) rs570443161
NM_004655.4(AXIN2):c.1443C>T (p.Leu481=) rs886053272
NM_004655.4(AXIN2):c.1743C>T (p.Arg581=) rs774932064
NM_004655.4(AXIN2):c.174C>T (p.Asn58=) rs763012548
NM_004655.4(AXIN2):c.1927G>C (p.Ala643Pro) rs748005374
NM_004655.4(AXIN2):c.1952C>G (p.Ser651Trp) rs74006838
NM_004655.4(AXIN2):c.2012G>C (p.Arg671Pro) rs765845684
NM_004655.4(AXIN2):c.2091G>A (p.Leu697=) rs2043915103
NM_004655.4(AXIN2):c.2124G>A (p.Ser708=) rs143243661
NM_004655.4(AXIN2):c.2124G>C (p.Ser708=) rs143243661
NM_004655.4(AXIN2):c.2405+4A>C rs377423720
NM_004655.4(AXIN2):c.339C>T (p.Ala113=) rs1598119867
NM_004655.4(AXIN2):c.435C>G (p.Val145=) rs111470596
NM_004655.4(AXIN2):c.629T>C (p.Met210Thr) rs529954883

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