ClinVar Miner

Variants in gene BIN1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
114 12 0 19 12 0 0 27

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

uncertain significance likely benign benign
uncertain significance 0 10 6
likely benign 10 0 19
benign 6 19 0

All variants with conflicting interpretations #

Total variants: 27
Download table as spreadsheet
HGVS dbSNP
NM_139343.2(BIN1):c.-27C>T rs11554586
NM_139343.2(BIN1):c.1003-16C>T rs547659375
NM_139343.2(BIN1):c.1131+9C>T rs138606879
NM_139343.2(BIN1):c.1132-7T>C rs115938552
NM_139343.2(BIN1):c.1143G>A (p.Pro381=) rs372360787
NM_139343.2(BIN1):c.1263+11C>T rs78967885
NM_139343.2(BIN1):c.1264-11_1270delCCTGTTACCAGCCCACAG rs776737413
NM_139343.2(BIN1):c.1292C>T (p.Pro431Leu) rs141119288
NM_139343.2(BIN1):c.1362G>T (p.Gly454=) rs61748155
NM_139343.2(BIN1):c.1595C>T (p.Thr532Met) rs112318500
NM_139343.2(BIN1):c.1611C>T (p.Asp537=) rs142523172
NM_139343.2(BIN1):c.30G>A (p.Thr10=) rs35535012
NM_139343.2(BIN1):c.384G>A (p.Thr128=) rs61748158
NM_139343.2(BIN1):c.486T>C (p.Thr162=) rs1060743
NM_139343.2(BIN1):c.696C>A (p.Asn232Lys) rs143820618
NM_139343.2(BIN1):c.698+10A>G rs72481904
NM_139343.2(BIN1):c.714C>T (p.Tyr238=) rs1137845
NM_139343.2(BIN1):c.775-4G>A rs61748157
NM_139343.2(BIN1):c.805G>A (p.Gly269Ser) rs372072916
NM_139343.2(BIN1):c.858-12C>A rs6720741
NM_139343.2(BIN1):c.858-5C>T rs75328896
NM_139343.2(BIN1):c.888C>T (p.Ser296=) rs114833236
NM_139343.2(BIN1):c.894G>A (p.Ser298=) rs2228955
NM_139343.2(BIN1):c.906C>T (p.Gly302=) rs371258305
NM_139343.2(BIN1):c.924C>T (p.Pro308=) rs367611371
NM_139343.2(BIN1):c.942C>T (p.His314=) rs370911793
NM_139343.2(BIN1):c.957C>T (p.Ala319=) rs2276579

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.