ClinVar Miner

Variants in gene BRAT1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
1115 46 0 20 13 0 3 36

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 6 2 0 0
likely pathogenic 6 0 1 0 0
uncertain significance 2 1 0 11 2
likely benign 0 0 11 0 14
benign 0 0 2 14 0

All variants with conflicting interpretations #

Total variants: 36
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_152743.4(BRAT1):c.1206C>T (p.Asp402=) rs7807895 0.01413
NM_152743.4(BRAT1):c.1867G>A (p.Gly623Ser) rs77015302 0.01031
NM_152743.4(BRAT1):c.1135-8C>A rs113613637 0.00936
NM_152743.4(BRAT1):c.962T>G (p.Leu321Arg) rs150942467 0.00675
NM_152743.4(BRAT1):c.1884C>T (p.Ala628=) rs142346283 0.00625
NM_152743.4(BRAT1):c.866G>C (p.Cys289Ser) rs140451075 0.00598
NM_152743.4(BRAT1):c.675C>T (p.Phe225=) rs139443843 0.00438
NM_152743.4(BRAT1):c.2353C>T (p.Arg785Trp) rs61729932 0.00249
NM_152743.4(BRAT1):c.1922C>T (p.Ala641Val) rs113030000 0.00206
NM_152743.4(BRAT1):c.1659C>T (p.Leu553=) rs61746940 0.00205
NM_152743.4(BRAT1):c.1862G>A (p.Arg621Gln) rs138077616 0.00198
NM_152743.4(BRAT1):c.2208G>T (p.Leu736=) rs61753093 0.00159
NM_152743.4(BRAT1):c.1828C>T (p.Arg610Trp) rs61753094 0.00152
NM_152743.4(BRAT1):c.1579C>T (p.Leu527=) rs151161353 0.00126
NM_152743.4(BRAT1):c.434C>T (p.Ala145Val) rs140833277 0.00095
NM_152743.4(BRAT1):c.1792C>T (p.His598Tyr) rs201523118 0.00088
NM_152743.4(BRAT1):c.1564G>C (p.Glu522Gln) rs145509776 0.00083
NM_152743.4(BRAT1):c.2041G>A (p.Glu681Lys) rs145833100 0.00079
NM_152743.4(BRAT1):c.1507C>T (p.Pro503Ser) rs147745609 0.00078
NM_152743.4(BRAT1):c.2147C>T (p.Ala716Val) rs140802292 0.00075
NM_152743.4(BRAT1):c.826G>A (p.Asp276Asn) rs146546197 0.00070
NM_152743.4(BRAT1):c.955G>A (p.Val319Ile) rs140903769 0.00034
NM_152743.4(BRAT1):c.1594G>A (p.Gly532Arg) rs142129866 0.00028
NM_152743.4(BRAT1):c.294dup (p.Leu99fs) rs776913277 0.00022
NM_152743.4(BRAT1):c.2340C>G (p.Asp780Glu) rs201045158 0.00021
NM_152743.4(BRAT1):c.1196G>A (p.Arg399Gln) rs371360176 0.00008
NM_152743.4(BRAT1):c.491C>T (p.Ala164Val) rs771600489 0.00004
NM_152743.4(BRAT1):c.1305G>T (p.Thr435=) rs145506790
NM_152743.4(BRAT1):c.1371_1395+16del rs1224820591
NM_152743.4(BRAT1):c.1499-1G>T rs1778987915
NM_152743.4(BRAT1):c.1710del (p.Gln571fs) rs756489141
NM_152743.4(BRAT1):c.2125_2128del (p.Phe709fs) rs763527391
NM_152743.4(BRAT1):c.2169T>A (p.Leu723=) rs150300694
NM_152743.4(BRAT1):c.393_422del (p.Gln132_Ala141del) rs1562582216
NM_152743.4(BRAT1):c.393_422dup (p.Gln132_Ala141dup) rs1562582216
NM_152743.4(BRAT1):c.638dup (p.Val214fs) rs730880324

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