Variants in gene CDKL5 with conflicting interpretations "likely benign" and "uncertain significance"

Submission 1 (likely benign) minimum review status:		Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status:		Submission 2 (uncertain significance) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 15

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HGVS	dbSNP	gnomAD frequency
NM_001323289.2(CDKL5):c.1892T>C (p.Ile631Thr)	rs144878564	0.00012
NM_001323289.2(CDKL5):c.2555C>T (p.Pro852Leu)	rs587783156	0.00012
NM_001323289.2(CDKL5):c.2200A>G (p.Thr734Ala)	rs55803460	0.00010
NM_001323289.2(CDKL5):c.1564T>G (p.Leu522Val)	rs781427744	0.00006
NM_001323289.2(CDKL5):c.2243A>G (p.Asn748Ser)	rs748459878	0.00005
NM_001323289.2(CDKL5):c.2469C>T (p.Pro823=)	rs369377144	0.00005
NM_001323289.2(CDKL5):c.2465G>A (p.Arg822His)	rs376429571	0.00004
NM_001323289.2(CDKL5):c.93A>G (p.Arg31=)	rs140332992	0.00004
NM_001323289.2(CDKL5):c.1002T>C (p.Ala334=)	rs756986206	0.00002
NM_001323289.2(CDKL5):c.1616G>C (p.Arg539Thr)	rs1356745875	0.00002
NM_001323289.2(CDKL5):c.2408C>T (p.Thr803Met)	rs1005844306	0.00002
NM_001323289.2(CDKL5):c.1676G>A (p.Arg559Gln)	rs1926294168	0.00001
NM_001323289.2(CDKL5):c.2152+10C>G	rs763466606	0.00001
NM_001323289.2(CDKL5):c.1455_1460del (p.Ala486_Lys487del)	rs587783114
NM_001323289.2(CDKL5):c.2157A>G (p.Pro719=)

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