Variants in gene CHEK2 with conflicting interpretations "uncertain significance" and "pathogenic"

Submission 1 (uncertain significance) minimum review status:		Submission 1 (uncertain significance) method:
Submission 2 (pathogenic) minimum review status:		Submission 2 (pathogenic) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 9

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HGVS	dbSNP	gnomAD frequency
NM_007194.4(CHEK2):c.470T>C (p.Ile157Thr)	rs17879961	0.00434
NM_007194.4(CHEK2):c.1427C>T (p.Thr476Met)	rs142763740	0.00032
NM_007194.4(CHEK2):c.444+1G>A	rs121908698	0.00009
NM_007194.4(CHEK2):c.485A>G (p.Asp162Gly)	rs587781652	0.00001
NM_007194.4(CHEK2):c.592+3A>T	rs587782849	0.00001
NM_007194.4(CHEK2):c.592G>C (p.Val198Leu)	rs1555926708
NM_007194.4(CHEK2):c.599T>C (p.Val200Ala)	rs2053696720
NM_007194.4(CHEK2):c.882AGA[1] (p.Glu295del)	rs771860071
NM_007194.4(CHEK2):c.902del (p.Leu301fs)	rs748005072

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