ClinVar Miner

Variants in gene DIS3L2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
469 22 0 7 12 0 0 19

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

uncertain significance likely benign benign
uncertain significance 0 9 3
likely benign 9 0 7
benign 3 7 0

All variants with conflicting interpretations #

Total variants: 19
Download table as spreadsheet
NM_152383.4(DIS3L2):c.1158C>T (p.Thr386=) rs539081624
NM_152383.4(DIS3L2):c.1170C>T (p.Leu390=) rs17272089
NM_152383.4(DIS3L2):c.1448G>A (p.Arg483Gln) rs148474013
NM_152383.4(DIS3L2):c.1488T>C (p.His496=) rs72998118
NM_152383.4(DIS3L2):c.1599C>T (p.His533=) rs760229466
NM_152383.4(DIS3L2):c.1680G>A (p.Leu560=) rs377644356
NM_152383.4(DIS3L2):c.1809G>A (p.Glu603=) rs748787779
NM_152383.4(DIS3L2):c.2067C>T (p.Tyr689=) rs186340144
NM_152383.4(DIS3L2):c.2124C>T (p.Asp708=) rs368518323
NM_152383.4(DIS3L2):c.2187C>T (p.Pro729=) rs75782436
NM_152383.4(DIS3L2):c.2424G>A (p.Gln808=) rs369113667
NM_152383.4(DIS3L2):c.2637C>T (p.Pro879=) rs376299829
NM_152383.4(DIS3L2):c.263C>T (p.Pro88Leu) rs202059499
NM_152383.4(DIS3L2):c.34C>T (p.Pro12Ser) rs723044
NM_152383.4(DIS3L2):c.426C>T (p.Pro142=) rs73001172
NM_152383.4(DIS3L2):c.456A>G (p.Gln152=) rs11887184
NM_152383.4(DIS3L2):c.519C>T (p.Ser173=) rs143680532
NM_152383.4(DIS3L2):c.702+10T>G rs184764939
NM_152383.4(DIS3L2):c.795C>T (p.Tyr265=) rs202042951

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