ClinVar Miner

Variants in gene DIS3L2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
1016 44 0 4 21 0 1 26

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 1 0 0
likely pathogenic 1 0 0 0 0
uncertain significance 1 0 0 14 7
likely benign 0 0 14 0 3
benign 0 0 7 3 0

All variants with conflicting interpretations #

Total variants: 26
Download table as spreadsheet
HGVS dbSNP
NM_152383.4(DIS3L2):c.1809G>A (p.Glu603=) rs748787779
NM_152383.4(DIS3L2):c.210+10A>G rs201117797
NM_152383.4(DIS3L2):c.2394+5G>A rs1489037110
NM_152383.5(DIS3L2):c.108G>A (p.Lys36=) rs371477071
NM_152383.5(DIS3L2):c.1158C>T (p.Thr386=) rs539081624
NM_152383.5(DIS3L2):c.1447C>G (p.Arg483Gly) rs186865544
NM_152383.5(DIS3L2):c.1599C>T (p.His533=) rs760229466
NM_152383.5(DIS3L2):c.1680G>A (p.Leu560=) rs377644356
NM_152383.5(DIS3L2):c.1836G>A (p.Pro612=) rs202227137
NM_152383.5(DIS3L2):c.1839C>T (p.Pro613=) rs187677159
NM_152383.5(DIS3L2):c.1908C>T (p.Ser636=) rs778830625
NM_152383.5(DIS3L2):c.2067C>T (p.Tyr689=) rs186340144
NM_152383.5(DIS3L2):c.2124C>T (p.Asp708=) rs368518323
NM_152383.5(DIS3L2):c.2151C>T (p.Ala717=) rs747739911
NM_152383.5(DIS3L2):c.2370C>T (p.Gly790=) rs199541622
NM_152383.5(DIS3L2):c.2424G>A (p.Gln808=) rs369113667
NM_152383.5(DIS3L2):c.2637C>T (p.Pro879=) rs376299829
NM_152383.5(DIS3L2):c.263C>T (p.Pro88Leu) rs202059499
NM_152383.5(DIS3L2):c.325dup (p.Asp109fs)
NM_152383.5(DIS3L2):c.410A>G (p.Tyr137Cys) rs201733073
NM_152383.5(DIS3L2):c.453G>A (p.Pro151=) rs567611268
NM_152383.5(DIS3L2):c.519C>T (p.Ser173=) rs143680532
NM_152383.5(DIS3L2):c.662C>G (p.Thr221Arg) rs201020526
NM_152383.5(DIS3L2):c.702+10T>G rs184764939
NM_152383.5(DIS3L2):c.795C>T (p.Tyr265=) rs202042951
NM_152383.5(DIS3L2):c.878C>A (p.Pro293His) rs187563594

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