ClinVar Miner

Variants in gene DNMT1 with conflicting interpretations "likely benign" and "uncertain significance"

Submission 1 (likely benign) minimum review status: Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status: Submission 2 (uncertain significance) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 25
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HGVS dbSNP gnomAD frequency
NM_001130823.3(DNMT1):c.150C>T (p.His50=) rs146112081 0.00182
NM_001130823.3(DNMT1):c.575C>T (p.Ala192Val) rs62621089 0.00023
NM_001130823.3(DNMT1):c.301C>T (p.Arg101Trp) rs369196079 0.00014
NM_001130823.3(DNMT1):c.2667C>T (p.Tyr889=) rs199832007 0.00013
NM_001130823.3(DNMT1):c.382C>A (p.Pro128Thr) rs146601335 0.00013
NM_001130823.3(DNMT1):c.3097C>T (p.Arg1033Trp) rs144533539 0.00011
NM_001130823.3(DNMT1):c.4876G>A (p.Glu1626Lys) rs201774098 0.00011
NM_001130823.3(DNMT1):c.868G>A (p.Glu290Lys) rs200024502 0.00011
NM_001130823.3(DNMT1):c.483T>C (p.Thr161=) rs764496230 0.00009
NM_001130823.3(DNMT1):c.2937C>T (p.Pro979=) rs150359172 0.00008
NM_001130823.3(DNMT1):c.919A>G (p.Lys307Glu) rs148831705 0.00008
NM_001130823.3(DNMT1):c.327C>T (p.Asn109=) rs144685297 0.00007
NM_001130823.3(DNMT1):c.4894G>C (p.Asp1632His) rs147118268 0.00005
NM_001130823.3(DNMT1):c.3117-4G>A rs781402268 0.00003
NM_001130823.3(DNMT1):c.2835C>T (p.Asn945=) rs539948794 0.00002
NM_001130823.3(DNMT1):c.867C>T (p.Asp289=) rs750916721 0.00002
NM_001130823.3(DNMT1):c.2260G>A (p.Val754Ile) rs762172122 0.00001
NM_001130823.3(DNMT1):c.3036C>G (p.Ile1012Met) rs376854079 0.00001
NM_001130823.3(DNMT1):c.3117-8G>A rs769623856 0.00001
NM_001130823.3(DNMT1):c.3537G>A (p.Thr1179=) rs761140414 0.00001
NM_001130823.3(DNMT1):c.4164C>T (p.Ser1388=) rs779701784 0.00001
NM_001130823.3(DNMT1):c.720A>G (p.Arg240=) rs760733624 0.00001
NM_001130823.3(DNMT1):c.1171-7C>T rs1168540279
NM_001130823.3(DNMT1):c.3524-5G>T
NM_001130823.3(DNMT1):c.410C>T (p.Thr137Met) rs377146699

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