Variants in gene FANCM with conflicting interpretations "uncertain significance" and "likely benign"

Submission 1 (uncertain significance) minimum review status:		Submission 1 (uncertain significance) method:
Submission 2 (likely benign) minimum review status:		Submission 2 (likely benign) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 44

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HGVS	dbSNP	gnomAD frequency
NM_020937.4(FANCM):c.1040C>T (p.Pro347Leu)	rs151071546	0.00243
NM_020937.4(FANCM):c.491A>C (p.His164Pro)	rs144278051	0.00176
NM_020937.4(FANCM):c.171G>C (p.Leu57Phe)	rs142007602	0.00161
NM_020937.4(FANCM):c.1576C>G (p.Leu526Val)	rs144215747	0.00147
NM_020937.4(FANCM):c.926A>C (p.Glu309Ala)	rs143006771	0.00091
NM_020937.4(FANCM):c.1237T>C (p.Tyr413His)	rs138225703	0.00082
NM_020937.4(FANCM):c.3296G>A (p.Arg1099His)	rs139382267	0.00082
NM_020937.4(FANCM):c.2517T>G (p.Ile839Met)	rs61744648	0.00068
NM_020937.4(FANCM):c.2859A>C (p.Lys953Asn)	rs142864437	0.00064
NM_020937.4(FANCM):c.2297A>G (p.Glu766Gly)	rs139946652	0.00053
NM_020937.4(FANCM):c.3681A>G (p.Leu1227=)	rs61749475	0.00047
NM_020937.4(FANCM):c.4084G>A (p.Asp1362Asn)	rs199895244	0.00038
NM_020937.4(FANCM):c.2267G>A (p.Arg756His)	rs142763060	0.00032
NM_020937.4(FANCM):c.4366C>T (p.Arg1456Cys)	rs200360968	0.00025
NM_020937.4(FANCM):c.5108A>G (p.His1703Arg)	rs146897650	0.00020
NM_020937.4(FANCM):c.4627C>T (p.Leu1543Phe)	rs139536545	0.00019
NM_020937.4(FANCM):c.2809C>T (p.Leu937Phe)	rs138274490	0.00017
NM_020937.4(FANCM):c.5848T>G (p.Leu1950Val)	rs146436929	0.00017
NM_020937.4(FANCM):c.2003-3T>C	rs777799598	0.00016
NM_020937.4(FANCM):c.4709G>A (p.Arg1570His)	rs201803784	0.00016
NM_020937.4(FANCM):c.1741C>T (p.Arg581Cys)	rs202171930	0.00015
NM_020937.4(FANCM):c.4959G>A (p.Met1653Ile)	rs143152888	0.00014
NM_020937.4(FANCM):c.30G>A (p.Gln10=)	rs145745979	0.00013
NM_020937.4(FANCM):c.5832G>T (p.Leu1944Phe)	rs201017015	0.00011
NM_020937.4(FANCM):c.2330A>G (p.Tyr777Cys)	rs200173413	0.00007
NM_020937.4(FANCM):c.1193G>A (p.Arg398Gln)	rs530233908	0.00006
NM_020937.4(FANCM):c.1996A>G (p.Arg666Gly)	rs78437454	0.00006
NM_020937.4(FANCM):c.3938G>C (p.Ser1313Thr)	rs771311008	0.00005
NM_020937.4(FANCM):c.4934G>A (p.Arg1645His)	rs377502779	0.00005
NM_020937.4(FANCM):c.1667A>G (p.Asp556Gly)	rs148810507	0.00003
NM_020937.4(FANCM):c.2158C>T (p.Pro720Ser)	rs751262177	0.00003
NM_020937.4(FANCM):c.242C>T (p.Ala81Val)	rs538464580	0.00002
NM_020937.4(FANCM):c.2968G>A (p.Val990Ile)	rs772477865	0.00002
NM_020937.4(FANCM):c.3663T>C (p.Phe1221=)	rs772996800	0.00002
NM_020937.4(FANCM):c.5066C>T (p.Ala1689Val)	rs759068569	0.00002
NM_020937.4(FANCM):c.4465G>A (p.Gly1489Arg)	rs183784665	0.00001
NM_020937.4(FANCM):c.5152G>A (p.Val1718Met)	rs371629950	0.00001
NM_020937.4(FANCM):c.5717-4T>A	rs781258517	0.00001
NM_020937.4(FANCM):c.1759A>G (p.Ile587Val)
NM_020937.4(FANCM):c.2160+10A>G	rs767254996
NM_020937.4(FANCM):c.2678A>G (p.Asp893Gly)	rs1023555775
NM_020937.4(FANCM):c.4005A>G (p.Lys1335=)	rs1888735204
NM_020937.4(FANCM):c.4859AAG[2] (p.Glu1622del)	rs765421461
NM_020937.4(FANCM):c.6010T>A (p.Ser2004Thr)	rs760258217

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