ClinVar Miner

Variants in gene FLNB with conflicting interpretations "likely benign" and "benign"

Submission 1 (likely benign) minimum review status: Submission 1 (likely benign) method:
Submission 2 (benign) minimum review status: Submission 2 (benign) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 67
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_001457.4(FLNB):c.6017A>G (p.Lys2006Arg) rs62621996 0.00994
NM_001457.4(FLNB):c.1919C>T (p.Thr640Met) rs62621999 0.00943
NM_001457.4(FLNB):c.3771G>A (p.Pro1257=) rs146851485 0.00794
NM_001457.4(FLNB):c.6956T>C (p.Ile2319Thr) rs116826041 0.00739
NM_001457.4(FLNB):c.669G>A (p.Pro223=) rs140815373 0.00527
NM_001457.4(FLNB):c.5646G>A (p.Pro1882=) rs114882667 0.00522
NM_001457.4(FLNB):c.3785G>C (p.Gly1262Ala) rs111330368 0.00503
NM_001457.4(FLNB):c.7099G>A (p.Val2367Ile) rs115747856 0.00488
NM_001457.4(FLNB):c.4671+11G>A rs115346578 0.00454
NM_001457.4(FLNB):c.4872C>T (p.Ile1624=) rs147426569 0.00436
NM_001457.4(FLNB):c.3090C>T (p.Tyr1030=) rs112968165 0.00406
NM_001457.4(FLNB):c.2382C>T (p.Asp794=) rs146159035 0.00360
NM_001457.4(FLNB):c.3240G>A (p.Pro1080=) rs77989135 0.00333
NM_001457.4(FLNB):c.3264C>T (p.Ser1088=) rs112864468 0.00322
NM_001457.4(FLNB):c.4222+19A>C rs146229370 0.00319
NM_001457.4(FLNB):c.362A>T (p.Tyr121Phe) rs147846832 0.00269
NM_001457.4(FLNB):c.292+14C>G rs200721532 0.00260
NM_001457.4(FLNB):c.1044C>T (p.Asp348=) rs111996979 0.00252
NM_001457.4(FLNB):c.4222+8A>G rs190025781 0.00248
NM_001457.4(FLNB):c.4377T>C (p.Val1459=) rs149921907 0.00232
NM_001457.4(FLNB):c.274A>G (p.Ile92Val) rs62622011 0.00229
NM_001457.4(FLNB):c.4362G>A (p.Pro1454=) rs150844992 0.00217
NM_001457.4(FLNB):c.1472T>C (p.Met491Thr) rs147575358 0.00203
NM_001457.4(FLNB):c.6231C>T (p.Asp2077=) rs145280904 0.00184
NM_001457.4(FLNB):c.6684C>T (p.Ile2228=) rs138416613 0.00170
NM_001457.4(FLNB):c.6642C>T (p.Phe2214=) rs140786324 0.00161
NM_001457.4(FLNB):c.6773-13C>A rs200653965 0.00149
NM_001457.4(FLNB):c.6741G>A (p.Ser2247=) rs143400214 0.00142
NM_001457.4(FLNB):c.4929C>T (p.Ala1643=) rs149070858 0.00140
NM_001457.4(FLNB):c.420G>A (p.Thr140=) rs192491895 0.00134
NM_001457.4(FLNB):c.7360G>A (p.Val2454Ile) rs146499414 0.00131
NM_001457.4(FLNB):c.6000T>C (p.Gly2000=) rs140926445 0.00127
NM_001457.4(FLNB):c.7668C>T (p.Cys2556=) rs144621434 0.00125
NM_001457.4(FLNB):c.3522G>A (p.Ser1174=) rs140993979 0.00111
NM_001457.4(FLNB):c.292+12G>C rs201148582 0.00066
NM_001457.4(FLNB):c.4672-11A>G rs72884428 0.00064
NM_001457.4(FLNB):c.6843C>T (p.Ile2281=) rs140332932 0.00062
NM_001457.4(FLNB):c.6680C>G (p.Ser2227Cys) rs138327769 0.00050
NM_001457.4(FLNB):c.1704G>A (p.Ala568=) rs139001948 0.00043
NM_001457.4(FLNB):c.7254C>T (p.Ser2418=) rs563382903 0.00031
NM_001457.4(FLNB):c.7255G>A (p.Val2419Ile) rs202143851 0.00024
NM_001457.4(FLNB):c.5887+8A>G rs143066905 0.00023
NM_001457.4(FLNB):c.1534G>A (p.Ala512Thr) rs201544295 0.00022
NM_001457.4(FLNB):c.3898+19G>A rs780062399 0.00021
NM_001457.4(FLNB):c.5445C>T (p.Tyr1815=) rs755702006 0.00019
NM_001457.4(FLNB):c.5769C>T (p.Ala1923=) rs201723447 0.00019
NM_001457.4(FLNB):c.7183G>A (p.Glu2395Lys) rs142023538 0.00019
NM_001457.4(FLNB):c.7198+20C>G rs201580886 0.00019
NM_001457.4(FLNB):c.4390+8T>A rs377095569 0.00018
NM_001457.4(FLNB):c.5785G>A (p.Asp1929Asn) rs146685642 0.00017
NM_001457.4(FLNB):c.2931G>A (p.Leu977=) rs574484752 0.00012
NM_001457.4(FLNB):c.6416G>A (p.Arg2139His) rs578244438 0.00010
NM_001457.4(FLNB):c.5220C>T (p.Asn1740=) rs531970315 0.00008
NM_001457.4(FLNB):c.5532C>T (p.Ile1844=) rs202240037 0.00008
NM_001457.4(FLNB):c.1873G>A (p.Glu625Lys) rs372998485 0.00007
NM_001457.4(FLNB):c.1278C>T (p.His426=) rs572259451 0.00003
NM_001457.4(FLNB):c.1107C>T (p.Asn369=) rs538953239 0.00002
NM_001457.4(FLNB):c.6829C>T (p.Leu2277=) rs150602768 0.00002
NM_001457.4(FLNB):c.7749G>A (p.Leu2583=) rs535252967 0.00002
NM_001457.4(FLNB):c.6755A>T (p.Tyr2252Phe) rs200567066 0.00001
NM_001457.4(FLNB):c.107G>A (p.Arg36His) rs142568031
NM_001457.4(FLNB):c.1327G>C (p.Val443Leu) rs200902568
NM_001457.4(FLNB):c.2622G>T (p.Gly874=)
NM_001457.4(FLNB):c.3163G>A (p.Val1055Met) rs9813235
NM_001457.4(FLNB):c.3724+36del rs56147140
NM_001457.4(FLNB):c.4515-24GT[4] rs151085835
NM_001457.4(FLNB):c.5343C>T (p.Asp1781=)

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.