ClinVar Miner

Variants in gene GLRA1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
82 11 11 7 2 0 2 20

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 11 1 1 1 1
likely pathogenic 1 0 0 0 0
uncertain significance 1 0 0 2 0
likely benign 1 0 2 0 6
benign 1 0 0 6 0

All variants with conflicting interpretations #

Total variants: 20
Download table as spreadsheet
HGVS dbSNP
NM_000171.3(GLRA1):c.1041G>A (p.Arg347=) rs75463357
NM_000171.3(GLRA1):c.1046G>A (p.Arg349Gln) rs139213838
NM_000171.3(GLRA1):c.1108G>A (p.Gly370Ser) rs116474260
NM_000171.3(GLRA1):c.117G>C (p.Ser39=) rs149023945
NM_000171.3(GLRA1):c.1214G>A (p.Arg405Gln) rs199561280
NM_000171.3(GLRA1):c.299G>A (p.Arg100His) rs281864914
NM_000171.3(GLRA1):c.390C>T (p.Asn130=) rs112970419
NM_000171.3(GLRA1):c.723G>C (p.Arg241=) rs76872663
NM_000171.3(GLRA1):c.896G>T (p.Arg299Leu) rs121918408
NM_000171.3(GLRA1):c.920A>G (p.Tyr307Cys) rs121918410
NM_000171.3(GLRA1):c.993C>T (p.Ala331=) rs17112272
NM_001146040.1(GLRA1):c.(?_-287)_(912+?)del
NM_001146040.1(GLRA1):c.690C>A (p.Tyr230Ter) rs121918415
NM_001146040.1(GLRA1):c.777C>G (p.Ser259Arg) rs121918417
NM_001146040.1(GLRA1):c.815T>A (p.Ile272Asn) rs121918409
NM_001146040.1(GLRA1):c.832C>A (p.Pro278Thr) rs121918413
NM_001146040.1(GLRA1):c.862G>A (p.Val288Met) rs121918416
NM_001146040.1(GLRA1):c.882G>C (p.Gln294His) rs121918411
NM_001146040.1(GLRA1):c.896G>A (p.Arg299Gln) rs121918408
NM_001146040.1(GLRA1):c.910A>G (p.Lys304Glu) rs121918412

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