ClinVar Miner

Variants in gene HCN4 with conflicting interpretations "likely benign" and "uncertain significance"

Submission 1 (likely benign) minimum review status: Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status: Submission 2 (uncertain significance) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 28
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HGVS dbSNP gnomAD frequency
NM_005477.3(HCN4):c.458A>G (p.Glu153Gly) rs560874115 0.00149
NM_005477.3(HCN4):c.1356C>T (p.Ser452=) rs148453034 0.00116
NM_005477.3(HCN4):c.3010C>T (p.Pro1004Ser) rs201418838 0.00084
NM_005477.3(HCN4):c.3577G>C (p.Glu1193Gln) rs200507617 0.00068
NM_005477.3(HCN4):c.2739G>A (p.Ala913=) rs373411041 0.00056
NM_005477.3(HCN4):c.1371+9G>A rs200303699 0.00048
NM_005477.3(HCN4):c.2800C>T (p.Arg934Cys) rs199638465 0.00045
NM_005477.3(HCN4):c.2181C>T (p.His727=) rs140354126 0.00036
NM_005477.3(HCN4):c.2730C>A (p.Phe910Leu) rs200814534 0.00014
NM_005477.3(HCN4):c.2025C>T (p.Ala675=) rs149033101 0.00013
NM_005477.3(HCN4):c.2701G>A (p.Ala901Thr) rs201742383 0.00012
NM_005477.3(HCN4):c.621C>G (p.Arg207=) rs727503958 0.00012
NM_005477.3(HCN4):c.2522C>T (p.Ser841Leu) rs200546024 0.00011
NM_005477.3(HCN4):c.3117G>A (p.Pro1039=) rs749785521 0.00011
NM_005477.3(HCN4):c.584C>T (p.Ala195Val) rs201375192 0.00011
NM_005477.3(HCN4):c.3195C>A (p.Val1065=) rs4493011 0.00010
NM_005477.3(HCN4):c.1815G>A (p.Thr605=) rs367753936 0.00009
NM_005477.3(HCN4):c.1243G>A (p.Val415Met) rs201978086 0.00007
NM_005477.3(HCN4):c.2864C>T (p.Pro955Leu) rs371562763 0.00005
NM_005477.3(HCN4):c.2845C>T (p.Arg949Trp) rs755614529 0.00004
NM_005477.3(HCN4):c.3582A>G (p.Pro1194=) rs375637572 0.00004
NM_005477.3(HCN4):c.2830G>A (p.Ala944Thr) rs777648103 0.00003
NM_005477.3(HCN4):c.2370T>C (p.Ser790=) rs747648596 0.00002
NM_005477.3(HCN4):c.1459G>A (p.Val487Met) rs202037304 0.00001
NM_005477.3(HCN4):c.2055C>T (p.Ser685=) rs886042819 0.00001
NM_005477.3(HCN4):c.2523G>A (p.Ser841=) rs768157473 0.00001
NM_005477.3(HCN4):c.2804C>T (p.Ser935Phe) rs775803239
NM_005477.3(HCN4):c.321C>T (p.Gly107=) rs1555479019

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