ClinVar Miner

Variants in gene KCND3 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
151 13 0 11 8 0 0 18

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 0 0 0
likely pathogenic 1 0 0 0 0
uncertain significance 0 0 0 6 3
likely benign 0 0 6 0 10
benign 0 0 3 10 0

All variants with conflicting interpretations #

Total variants: 18
Download table as spreadsheet
NM_004980.4(KCND3):c.1041G>A (p.Ser347=) rs369361457
NM_004980.4(KCND3):c.1062C>A (p.Ile354=) rs150934088
NM_004980.4(KCND3):c.1106+10C>T rs377267051
NM_004980.4(KCND3):c.1131G>T (p.Thr377=) rs148428571
NM_004980.4(KCND3):c.117T>C (p.Asp39=) rs12720446
NM_004980.4(KCND3):c.1292G>A (p.Arg431His) rs771703569
NM_004980.4(KCND3):c.1348C>T (p.Leu450Phe) rs150401343
NM_004980.4(KCND3):c.1354G>A (p.Glu452Lys) rs200532657
NM_004980.4(KCND3):c.1456A>G (p.Thr486Ala) rs149008060
NM_004980.4(KCND3):c.1573A>G (p.Met525Val) rs145890206
NM_004980.4(KCND3):c.186G>A (p.Pro62=) rs1411627342
NM_004980.4(KCND3):c.1959C>T (p.Ser653=) rs147087785
NM_004980.4(KCND3):c.264C>T (p.Pro88=) rs17221819
NM_004980.4(KCND3):c.459G>A (p.Ser153=) rs755206508
NM_004980.4(KCND3):c.5C>A (p.Ala2Glu) rs201340369
NM_004980.4(KCND3):c.627G>C (p.Thr209=) rs149299911
NM_004980.4(KCND3):c.633G>T (p.Pro211=) rs35131566
NM_004980.4(KCND3):c.641A>G (p.Lys214Arg) rs142744204

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.