ClinVar Miner

Variants in gene KRAS with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
87 104 0 34 7 1 5 43

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign drug response
pathogenic 0 22 3 0 0 1
likely pathogenic 22 0 2 0 0 1
uncertain significance 3 2 0 6 4 0
likely benign 0 0 6 0 12 0
benign 0 0 4 12 0 0
drug response 1 1 0 0 0 0

All variants with conflicting interpretations #

Total variants: 43
Download table as spreadsheet
NM_004985.5(KRAS):c.-27C>T rs587781013
NM_004985.5(KRAS):c.-48G>A rs532564755
NM_004985.5(KRAS):c.35G>A (p.Gly12Asp) rs121913529
NM_004985.5(KRAS):c.35G>T (p.Gly12Val) rs121913529
NM_004985.5(KRAS):c.451-14T>C rs372508498
NM_033360.4(KRAS):c.*12A>G rs104894360
NM_033360.4(KRAS):c.*20T>G rs397517042
NM_033360.4(KRAS):c.*298T>G rs712
NM_033360.4(KRAS):c.*73T>C rs1137282
NM_033360.4(KRAS):c.*82_*84GAA[1] rs397517043
NM_033360.4(KRAS):c.-160A>G rs727503111
NM_033360.4(KRAS):c.101C>G (p.Pro34Arg) rs104894366
NM_033360.4(KRAS):c.108A>G (p.Ile36Met) rs727503109
NM_033360.4(KRAS):c.112-5C>T rs376520586
NM_033360.4(KRAS):c.13A>G (p.Lys5Glu) rs193929331
NM_033360.4(KRAS):c.15A>T (p.Lys5Asn) rs104894361
NM_033360.4(KRAS):c.175G>A (p.Ala59Thr) rs121913528
NM_033360.4(KRAS):c.179G>T (p.Gly60Val) rs727503108
NM_033360.4(KRAS):c.182A>C (p.Gln61Pro) rs121913240
NM_033360.4(KRAS):c.182A>T (p.Gln61Leu) rs121913240
NM_033360.4(KRAS):c.183A>C (p.Gln61His) rs17851045
NM_033360.4(KRAS):c.183A>T (p.Gln61His) rs17851045
NM_033360.4(KRAS):c.194G>T (p.Ser65Ile) rs1555194026
NM_033360.4(KRAS):c.198A>G (p.Ala66=) rs200229810
NM_033360.4(KRAS):c.24A>G (p.Val8=) rs147406419
NM_033360.4(KRAS):c.264A>G (p.Lys88=) rs370920665
NM_033360.4(KRAS):c.34G>A (p.Gly12Ser) rs121913530
NM_033360.4(KRAS):c.34G>T (p.Gly12Cys) rs121913530
NM_033360.4(KRAS):c.351A>C (p.Lys117Asn) rs770248150
NM_033360.4(KRAS):c.35G>C (p.Gly12Ala) rs121913529
NM_033360.4(KRAS):c.38G>A (p.Gly13Asp) rs112445441
NM_033360.4(KRAS):c.38G>T (p.Gly13Val) rs112445441
NM_033360.4(KRAS):c.436G>A (p.Ala146Thr) rs121913527
NM_033360.4(KRAS):c.436G>C (p.Ala146Pro) rs121913527
NM_033360.4(KRAS):c.436G>T (p.Ala146Ser) rs121913527
NM_033360.4(KRAS):c.439A>G (p.Lys147Glu) rs387907206
NM_033360.4(KRAS):c.496T>C (p.Tyr166His) rs397517476
NM_033360.4(KRAS):c.5-9G>A rs12313763
NM_033360.4(KRAS):c.540T>A (p.Cys180Ter) rs373169526
NM_033360.4(KRAS):c.565A>C (p.Met189Leu) rs201170656
NM_033360.4(KRAS):c.57G>C (p.Leu19Phe) rs121913538
NM_033360.4(KRAS):c.65A>G (p.Gln22Arg) rs727503110
NM_033360.4(KRAS):c.90C>T (p.Asp30=) rs113623140

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