ClinVar Miner

Variants in gene LAMA2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
1497 233 3 83 107 1 10 180

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign drug response protective other
pathogenic 3 21 7 0 0 0 0 0
likely pathogenic 22 0 3 1 1 1 1 1
uncertain significance 7 2 0 101 25 0 0 0
likely benign 0 0 101 0 61 0 0 0
benign 0 0 25 61 0 0 0 0

All variants with conflicting interpretations #

Total variants: 180
Download table as spreadsheet
HGVS dbSNP
NM_000426.3(LAMA2):c.112+1G>A rs398123367
NM_000426.3(LAMA2):c.1206+11C>T rs115007959
NM_000426.3(LAMA2):c.12del (p.Ala5fs) rs1554312639
NM_000426.3(LAMA2):c.1303C>T (p.Arg435Ter) rs773209126
NM_000426.3(LAMA2):c.1308T>G (p.Gly436=) rs41285286
NM_000426.3(LAMA2):c.1400A>G (p.Lys467Arg) rs138162760
NM_000426.3(LAMA2):c.1403C>G (p.Ala468Gly) rs111695726
NM_000426.3(LAMA2):c.1467+1G>A rs1554234161
NM_000426.3(LAMA2):c.1491T>C (p.Cys497=) rs2306220
NM_000426.3(LAMA2):c.1533T>C (p.Asn511=) rs9492266
NM_000426.3(LAMA2):c.1580G>A (p.Cys527Tyr) rs121913574
NM_000426.3(LAMA2):c.1621A>G (p.Ser541Gly) rs141363186
NM_000426.3(LAMA2):c.1634T>A (p.Leu545Gln) rs118083923
NM_000426.3(LAMA2):c.1650C>T (p.Gly550=) rs899353
NM_000426.3(LAMA2):c.1701C>T (p.Ile567=) rs111381107
NM_000426.3(LAMA2):c.1716G>C (p.Ala572=) rs758682648
NM_000426.3(LAMA2):c.1762del (p.Ala588fs) rs786205654
NM_000426.3(LAMA2):c.1782+10C>T rs200030296
NM_000426.3(LAMA2):c.1782+14T>C rs191215452
NM_000426.3(LAMA2):c.1798G>A (p.Gly600Arg) rs36044314
NM_000426.3(LAMA2):c.1814C>T (p.Thr605Ile) rs112388307
NM_000426.3(LAMA2):c.1893_1897del (p.Asp631fs) rs746844753
NM_000426.3(LAMA2):c.1930C>G (p.His644Asp) rs35879899
NM_000426.3(LAMA2):c.2037G>C (p.Ala679=) rs398123369
NM_000426.3(LAMA2):c.2049_2050delAG rs202247790
NM_000426.3(LAMA2):c.2115T>G (p.Leu705=) rs149753273
NM_000426.3(LAMA2):c.2187G>C (p.Gly729=) rs142345851
NM_000426.3(LAMA2):c.2217G>T (p.Trp739Cys) rs192317605
NM_000426.3(LAMA2):c.2304C>T (p.Asp768=) rs142126511
NM_000426.3(LAMA2):c.2323-18T>A rs199846930
NM_000426.3(LAMA2):c.237G>A (p.Arg79=) rs201402165
NM_000426.3(LAMA2):c.2382C>T (p.Gly794=) rs147744763
NM_000426.3(LAMA2):c.2427T>C (p.Cys809=) rs778050587
NM_000426.3(LAMA2):c.2430A>C (p.Pro810=) rs147572139
NM_000426.3(LAMA2):c.2451-2A>G rs993196576
NM_000426.3(LAMA2):c.2462C>T (p.Thr821Met) rs117422805
NM_000426.3(LAMA2):c.2476C>T (p.Arg826Trp) rs118147866
NM_000426.3(LAMA2):c.255C>T (p.Ile85=) rs142083777
NM_000426.3(LAMA2):c.2584T>C (p.Cys862Arg) rs121913573
NM_000426.3(LAMA2):c.2736G>A (p.Ala912=) rs142671449
NM_000426.3(LAMA2):c.2756G>T (p.Arg919Leu) rs35277491
NM_000426.3(LAMA2):c.2856+13G>A rs149487202
NM_000426.3(LAMA2):c.2857-13C>T rs201188972
NM_000426.3(LAMA2):c.2901C>A (p.Cys967Ter) rs121913577
NM_000426.3(LAMA2):c.2993G>A (p.Arg998His) rs144946631
NM_000426.3(LAMA2):c.3004G>A (p.Gly1002Ser) rs200953311
NM_000426.3(LAMA2):c.3279C>T (p.Cys1093=) rs371376404
NM_000426.3(LAMA2):c.3296A>G (p.Asn1099Ser) rs35065563
NM_000426.3(LAMA2):c.3429C>A (p.Ile1143=) rs200646230
NM_000426.3(LAMA2):c.3556-13T>A rs775278003
NM_000426.3(LAMA2):c.3556-15T>G rs17741922
NM_000426.3(LAMA2):c.3582T>C (p.Ile1194=) rs137962409
NM_000426.3(LAMA2):c.3585A>G (p.Leu1195=) rs780444488
NM_000426.3(LAMA2):c.3597T>C (p.Asp1199=) rs199904029
NM_000426.3(LAMA2):c.3613A>G (p.Thr1205Ala) rs35889149
NM_000426.3(LAMA2):c.3645A>G (p.Pro1215=) rs794727396
NM_000426.3(LAMA2):c.3718C>T (p.Gln1240Ter) rs121913569
NM_000426.3(LAMA2):c.3750G>T (p.Gly1250=) rs754604600
NM_000426.3(LAMA2):c.3925-6T>A rs372612467
NM_000426.3(LAMA2):c.4002T>G (p.Tyr1334Ter) rs1562451730
NM_000426.3(LAMA2):c.411G>A (p.Ala137=) rs149347601
NM_000426.3(LAMA2):c.4157A>T (p.Tyr1386Phe) rs560139751
NM_000426.3(LAMA2):c.4176+9C>T rs117116822
NM_000426.3(LAMA2):c.4301C>T (p.Ser1434Leu) rs368379507
NM_000426.3(LAMA2):c.4348C>T (p.Arg1450Ter) rs200923373
NM_000426.3(LAMA2):c.4349G>A (p.Arg1450Gln) rs148905630
NM_000426.3(LAMA2):c.4436+8T>C rs192650285
NM_000426.3(LAMA2):c.4437-5T>A rs41285288
NM_000426.3(LAMA2):c.4470C>T (p.Asp1490=) rs35089085
NM_000426.3(LAMA2):c.4487C>T (p.Ala1496Val) rs147077184
NM_000426.3(LAMA2):c.4523+1G>A rs398123375
NM_000426.3(LAMA2):c.4523G>A (p.Arg1508Lys) rs770084568
NM_000426.3(LAMA2):c.4717+1G>T rs1131691660
NM_000426.3(LAMA2):c.4749C>T (p.Leu1583=) rs754850670
NM_000426.3(LAMA2):c.4750G>A (p.Gly1584Ser) rs117781224
NM_000426.3(LAMA2):c.4772A>G (p.Gln1591Arg) rs143986011
NM_000426.3(LAMA2):c.4926A>G (p.Thr1642=) rs62421010
NM_000426.3(LAMA2):c.4935C>A (p.Thr1645=) rs35579821
NM_000426.3(LAMA2):c.4944C>T (p.Asn1648=) rs111632017
NM_000426.3(LAMA2):c.4959+6G>T rs148060790
NM_000426.3(LAMA2):c.4993G>A (p.Gly1665Arg) rs373997222
NM_000426.3(LAMA2):c.5021G>A (p.Arg1674Lys) rs143333246
NM_000426.3(LAMA2):c.5072-10C>A rs552989582
NM_000426.3(LAMA2):c.5072-6del rs398123376
NM_000426.3(LAMA2):c.5121C>T (p.Asp1707=) rs151199929
NM_000426.3(LAMA2):c.5247C>T (p.Ala1749=) rs149951387
NM_000426.3(LAMA2):c.5280G>A (p.Glu1760=) rs376693904
NM_000426.3(LAMA2):c.5290dup (p.Glu1764fs) rs1415944134
NM_000426.3(LAMA2):c.5382A>G (p.Thr1794=) rs565429072
NM_000426.3(LAMA2):c.5469C>T (p.Ser1823=) rs753886576
NM_000426.3(LAMA2):c.5476C>T (p.Arg1826Ter) rs747349942
NM_000426.3(LAMA2):c.5530C>A (p.Arg1844Ser) rs56173620
NM_000426.3(LAMA2):c.5530C>T (p.Arg1844Cys) rs56173620
NM_000426.3(LAMA2):c.5558T>G (p.Ile1853Arg) rs141911213
NM_000426.3(LAMA2):c.5562+5G>C rs771046502
NM_000426.3(LAMA2):c.5601T>G (p.Ser1867=) rs780368037
NM_000426.3(LAMA2):c.5633C>T (p.Ser1878Phe) rs139586720
NM_000426.3(LAMA2):c.5670G>T (p.Val1890=) rs374587087
NM_000426.3(LAMA2):c.5688C>T (p.His1896=) rs573779258
NM_000426.3(LAMA2):c.5689G>A (p.Ala1897Thr) rs200518204
NM_000426.3(LAMA2):c.5909G>C (p.Cys1970Ser) rs148451013
NM_000426.3(LAMA2):c.5969-4G>A rs566302197
NM_000426.3(LAMA2):c.6002G>A (p.Arg2001Lys) rs151009169
NM_000426.3(LAMA2):c.6150T>C (p.Asp2050=) rs114766691
NM_000426.3(LAMA2):c.6161A>G (p.Gln2054Arg) rs56035053
NM_000426.3(LAMA2):c.6167C>A (p.Thr2056Lys) rs73775407
NM_000426.3(LAMA2):c.6206A>G (p.Tyr2069Cys) rs117884199
NM_000426.3(LAMA2):c.6234A>G (p.Lys2078=) rs56920166
NM_000426.3(LAMA2):c.6279C>T (p.Ala2093=) rs141190803
NM_000426.3(LAMA2):c.6345C>T (p.Pro2115=) rs200364660
NM_000426.3(LAMA2):c.6426T>C (p.Asn2142=) rs150730793
NM_000426.3(LAMA2):c.6429+10T>G rs770063449
NM_000426.3(LAMA2):c.6429+8C>A rs199773264
NM_000426.3(LAMA2):c.6438A>G (p.Val2146=) rs755485519
NM_000426.3(LAMA2):c.6506A>G (p.Asn2169Ser) rs144845618
NM_000426.3(LAMA2):c.6539A>T (p.Asp2180Val) rs567385461
NM_000426.3(LAMA2):c.6567C>T (p.Ala2189=) rs748650667
NM_000426.3(LAMA2):c.6629T>C (p.Val2210Ala) rs78880369
NM_000426.3(LAMA2):c.6649G>A (p.Val2217Ile) rs147857398
NM_000426.3(LAMA2):c.6697G>A (p.Val2233Ile) rs150945378
NM_000426.3(LAMA2):c.6708-3A>C rs112637707
NM_000426.3(LAMA2):c.675C>T (p.Ala225=) rs139665175
NM_000426.3(LAMA2):c.6786G>A (p.Ser2262=) rs398123382
NM_000426.3(LAMA2):c.6788C>T (p.Thr2263Met) rs56209257
NM_000426.3(LAMA2):c.7058G>A (p.Arg2353His) rs548483084
NM_000426.3(LAMA2):c.7111T>G (p.Phe2371Val) rs150644209
NM_000426.3(LAMA2):c.7118C>T (p.Ser2373Leu) rs758887080
NM_000426.3(LAMA2):c.7153C>T (p.Leu2385=) rs1281520681
NM_000426.3(LAMA2):c.715C>T (p.Arg239Cys) rs145465528
NM_000426.3(LAMA2):c.7300+10T>A rs200469923
NM_000426.3(LAMA2):c.7344T>C (p.Asn2448=) rs199931560
NM_000426.3(LAMA2):c.7395T>C (p.Asp2465=) rs140483001
NM_000426.3(LAMA2):c.7431A>T (p.Arg2477Ser) rs34367843
NM_000426.3(LAMA2):c.7440-9G>A rs369558532
NM_000426.3(LAMA2):c.7479C>T (p.Ser2493=) rs368989339
NM_000426.3(LAMA2):c.74C>T (p.Pro25Leu) rs145310035
NM_000426.3(LAMA2):c.7640G>A (p.Gly2547Glu) rs115488979
NM_000426.3(LAMA2):c.7869A>G (p.Glu2623=) rs140658201
NM_000426.3(LAMA2):c.7881T>G (p.His2627Gln) rs202247792
NM_000426.3(LAMA2):c.7888C>T (p.Arg2630Ter) rs727502851
NM_000426.3(LAMA2):c.7965C>A (p.Ile2655=) rs141101234
NM_000426.3(LAMA2):c.8028T>C (p.Asn2676=) rs35313209
NM_000426.3(LAMA2):c.8124T>A (p.Gly2708=) rs34997144
NM_000426.3(LAMA2):c.8211A>C (p.Pro2737=) rs369596190
NM_000426.3(LAMA2):c.8223G>A (p.Thr2741=) rs150596964
NM_000426.3(LAMA2):c.8244+3_8244+6del rs746678525
NM_000426.3(LAMA2):c.8245-2A>G rs914395925
NM_000426.3(LAMA2):c.8298C>T (p.Phe2766=) rs145295628
NM_000426.3(LAMA2):c.8464T>C (p.Leu2822=) rs199570699
NM_000426.3(LAMA2):c.8528A>G (p.Asn2843Ser) rs73599293
NM_000426.3(LAMA2):c.8548-10T>C rs113644365
NM_000426.3(LAMA2):c.8586T>C (p.Tyr2862=) rs142451929
NM_000426.3(LAMA2):c.8684C>G (p.Thr2895Ser) rs200705442
NM_000426.3(LAMA2):c.8691A>G (p.Arg2897=) rs2228599
NM_000426.3(LAMA2):c.8692A>C (p.Arg2898=) rs200718262
NM_000426.3(LAMA2):c.8728G>A (p.Val2910Ile) rs141479751
NM_000426.3(LAMA2):c.8755C>T (p.Pro2919Ser) rs143026295
NM_000426.3(LAMA2):c.8842G>A (p.Gly2948Ser) rs143638361
NM_000426.3(LAMA2):c.8890G>T (p.Val2964Leu) rs202159946
NM_000426.3(LAMA2):c.8918C>T (p.Thr2973Met) rs145842163
NM_000426.3(LAMA2):c.8982T>C (p.Asp2994=) rs79374915
NM_000426.3(LAMA2):c.8988+15T>C rs201041465
NM_000426.3(LAMA2):c.8989-12C>G rs144860334
NM_000426.3(LAMA2):c.9060G>A (p.Leu3020=) rs368896579
NM_000426.3(LAMA2):c.9123C>T (p.Val3041=) rs61749497
NM_000426.3(LAMA2):c.9211+6T>C rs201375881
NM_000426.3(LAMA2):c.9212-11G>A rs770088527
NM_000426.3(LAMA2):c.9212-1G>A rs398123391
NM_000426.3(LAMA2):c.922G>A (p.Glu308Lys) rs146462599
NM_000426.3(LAMA2):c.9240C>A (p.Thr3080=) rs759819184
NM_000426.3(LAMA2):c.9253C>T rs121913571
NM_000426.3(LAMA2):c.9340G>A (p.Val3114Ile) rs200796753
NM_000426.3(LAMA2):c.946G>A (p.Asp316Asn) rs141340479
NM_000426.4(LAMA2):c.1586G>A rs370691060
NM_000426.4(LAMA2):c.5553C>T (p.Ser1851=)
NM_000426.4(LAMA2):c.7750-1713_7899-2153del
NM_000426.4(LAMA2):c.8282T>C (p.Ile2761Thr) rs115650537
NM_000426.4(LAMA2):c.9171A>C (p.Ser3057=)
NM_001079823.2(LAMA2):c.2556del (p.Phe852fs) rs750731624
Single allele

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.