ClinVar Miner

Variants in gene LAMB2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
295 31 0 8 18 0 0 25

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

uncertain significance likely benign benign
uncertain significance 0 14 4
likely benign 14 0 8
benign 4 8 0

All variants with conflicting interpretations #

Total variants: 25
Download table as spreadsheet
HGVS dbSNP
NM_002292.4(LAMB2):c.109C>G (p.Pro37Ala) rs144765752
NM_002292.4(LAMB2):c.1206G>A (p.Arg402=) rs201999373
NM_002292.4(LAMB2):c.1305C>T (p.Ser435=) rs144530798
NM_002292.4(LAMB2):c.1391G>A (p.Arg464His) rs188487818
NM_002292.4(LAMB2):c.2099G>A (p.Gly700Glu) rs142860588
NM_002292.4(LAMB2):c.2307C>T (p.Leu769=) rs147076626
NM_002292.4(LAMB2):c.2322C>G (p.Thr774=) rs142116851
NM_002292.4(LAMB2):c.2489-7C>T rs374958213
NM_002292.4(LAMB2):c.253G>A (p.Glu85Lys) rs140371771
NM_002292.4(LAMB2):c.261G>A (p.Lys87=) rs149408554
NM_002292.4(LAMB2):c.2922G>C (p.Gly974=) rs145465720
NM_002292.4(LAMB2):c.3582C>T (p.Phe1194=) rs138540017
NM_002292.4(LAMB2):c.3645G>A (p.Ala1215=) rs13082063
NM_002292.4(LAMB2):c.3858G>T (p.Val1286=) rs34967349
NM_002292.4(LAMB2):c.4163G>A (p.Arg1388Gln) rs146522641
NM_002292.4(LAMB2):c.4878G>A (p.Arg1626=) rs148648480
NM_002292.4(LAMB2):c.5061G>T (p.Thr1687=) rs150465100
NM_002292.4(LAMB2):c.5109C>T (p.Arg1703=) rs151292828
NM_002292.4(LAMB2):c.510C>T (p.Arg170=) rs149856537
NM_002292.4(LAMB2):c.5142G>A (p.Lys1714=) rs139511264
NM_002292.4(LAMB2):c.5166A>G (p.Gln1722=) rs114485284
NM_002292.4(LAMB2):c.76+10C>T rs370554848
NM_002292.4(LAMB2):c.795G>A (p.Glu265=) rs375953746
NM_002292.4(LAMB2):c.816T>C (p.Tyr272=) rs151251039
NM_002292.4(LAMB2):c.915+6G>A rs2071677

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