ClinVar Miner

Variants in gene LAMC3 with conflicting interpretations "likely benign" and "uncertain significance"

Submission 1 (likely benign) minimum review status: Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status: Submission 2 (uncertain significance) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 40
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HGVS dbSNP gnomAD frequency
NM_006059.4(LAMC3):c.-2C>T rs137883250 0.01424
NM_006059.4(LAMC3):c.4092C>T (p.Ser1364=) rs141724499 0.00360
NM_006059.4(LAMC3):c.2891-8C>T rs199535979 0.00339
NM_006059.4(LAMC3):c.2517G>A (p.Thr839=) rs140540789 0.00292
NM_006059.4(LAMC3):c.4160C>T (p.Ala1387Val) rs141497885 0.00258
NM_006059.4(LAMC3):c.4130C>T (p.Thr1377Ile) rs144662546 0.00189
NM_006059.4(LAMC3):c.1520-6G>A rs192031352 0.00175
NM_006059.4(LAMC3):c.2066C>T (p.Pro689Leu) rs113443891 0.00123
NM_006059.4(LAMC3):c.2276G>A (p.Gly759Asp) rs150859618 0.00084
NM_006059.4(LAMC3):c.2227A>G (p.Asn743Asp) rs36030184 0.00079
NM_006059.4(LAMC3):c.3374C>T (p.Ser1125Leu) rs151213335 0.00078
NM_006059.4(LAMC3):c.3674T>C (p.Val1225Ala) rs138481447 0.00068
NM_006059.4(LAMC3):c.2987G>A (p.Arg996His) rs113785045 0.00063
NM_006059.4(LAMC3):c.3319G>A (p.Gly1107Arg) rs144118534 0.00060
NM_006059.4(LAMC3):c.1547T>G (p.Val516Gly) rs549607103 0.00054
NM_006059.4(LAMC3):c.2238G>A (p.Ala746=) rs141918703 0.00044
NM_006059.4(LAMC3):c.1019G>A (p.Arg340Gln) rs149004188 0.00037
NM_006059.4(LAMC3):c.290A>G (p.Gln97Arg) rs141758463 0.00031
NM_006059.4(LAMC3):c.4415G>A (p.Arg1472Gln) rs137894550 0.00029
NM_006059.4(LAMC3):c.2390C>T (p.Pro797Leu) rs150965854 0.00018
NM_006059.4(LAMC3):c.2468A>G (p.Asn823Ser) rs140325029 0.00017
NM_006059.4(LAMC3):c.1051C>T (p.Arg351Cys) rs201626968 0.00014
NM_006059.4(LAMC3):c.944G>A (p.Arg315Gln) rs45444592 0.00012
NM_006059.4(LAMC3):c.2949C>T (p.Cys983=) rs373660982 0.00008
NM_006059.4(LAMC3):c.4660C>T (p.Arg1554Cys) rs375971925 0.00006
NM_006059.4(LAMC3):c.3566C>T (p.Ala1189Val) rs369839636 0.00004
NM_006059.4(LAMC3):c.686T>C (p.Val229Ala) rs149485800 0.00004
NM_006059.4(LAMC3):c.4348C>T (p.Arg1450Cys) rs201785610 0.00003
NM_006059.4(LAMC3):c.4477+3A>G rs202112145 0.00003
NM_006059.4(LAMC3):c.1130G>A (p.Arg377Gln) rs375139277 0.00002
NM_006059.4(LAMC3):c.1414C>A (p.His472Asn) rs145387373 0.00001
NM_006059.4(LAMC3):c.4031-10G>A rs555619019 0.00001
NM_006059.4(LAMC3):c.4031-4G>A rs765657893 0.00001
NM_006059.4(LAMC3):c.4698C>T (p.Ser1566=) rs754122699 0.00001
NM_006059.4(LAMC3):c.1939G>C (p.Gly647Arg) rs144242690
NM_006059.4(LAMC3):c.3069+8G>T rs563444562
NM_006059.4(LAMC3):c.3250G>C (p.Glu1084Gln) rs146221263
NM_006059.4(LAMC3):c.3379G>A (p.Glu1127Lys) rs140955110
NM_006059.4(LAMC3):c.4146G>C (p.Arg1382Ser) rs147092908
NM_006059.4(LAMC3):c.42_50dup (p.Pro15_Ala17dup) rs1057520165

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