ClinVar Miner

Variants in gene LARS2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
101 24 0 15 3 0 0 17

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 4 0 0 0
likely pathogenic 4 0 0 0 0
uncertain significance 0 0 0 3 1
likely benign 0 0 3 0 11
benign 0 0 1 11 0

All variants with conflicting interpretations #

Total variants: 17
Download table as spreadsheet
NM_015340.4(LARS2):c.1383T>C (p.Ile461=) rs35347543
NM_015340.4(LARS2):c.1552G>A (p.Asp518Asn) rs116826217
NM_015340.4(LARS2):c.1565C>A (p.Thr522Asn) rs199589947
NM_015340.4(LARS2):c.1622+8G>A rs202009605
NM_015340.4(LARS2):c.1692C>T (p.Ala564=) rs149911756
NM_015340.4(LARS2):c.1779G>C (p.Leu593=) rs148167639
NM_015340.4(LARS2):c.2099C>T (p.Thr700Ile) rs1575308774
NM_015340.4(LARS2):c.2203G>A (p.Val735Ile) rs141011840
NM_015340.4(LARS2):c.2307C>T (p.Ser769=) rs143838895
NM_015340.4(LARS2):c.235-12G>A rs75240042
NM_015340.4(LARS2):c.255C>T (p.Tyr85=) rs114881088
NM_015340.4(LARS2):c.2602G>A (p.Glu868Lys) rs34965084
NM_015340.4(LARS2):c.388G>A (p.Ala130Thr) rs1575240334
NM_015340.4(LARS2):c.683G>A (p.Arg228His) rs770440975
NM_015340.4(LARS2):c.765G>A (p.Ala255=) rs116272561
NM_015340.4(LARS2):c.945G>C (p.Ser315=) rs145135580
NM_015340.4(LARS2):c.972C>A (p.His324Gln) rs71645922

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