ClinVar Miner

Variants in gene LINS1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
70 6 0 8 6 0 0 13

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

uncertain significance likely benign benign
uncertain significance 0 5 2
likely benign 5 0 8
benign 2 8 0

All variants with conflicting interpretations #

Total variants: 13
Download table as spreadsheet
NM_001040616.3(LINS1):c.1124C>T (p.Thr375Ile) rs143097819
NM_001040616.3(LINS1):c.1194A>G (p.Gln398=) rs138347314
NM_001040616.3(LINS1):c.1285C>T (p.Leu429=) rs141962847
NM_001040616.3(LINS1):c.1302G>A (p.Pro434=) rs148166631
NM_001040616.3(LINS1):c.1479T>C (p.Cys493=) rs144513217
NM_001040616.3(LINS1):c.1813A>G (p.Met605Val) rs141855950
NM_001040616.3(LINS1):c.1887C>T (p.Tyr629=) rs61999313
NM_001040616.3(LINS1):c.2027A>G (p.Glu676Gly) rs150348863
NM_001040616.3(LINS1):c.2119G>A (p.Gly707Arg) rs74039425
NM_001040616.3(LINS1):c.52G>A (p.Gly18Arg) rs141782332
NM_001040616.3(LINS1):c.615A>G (p.Ser205=) rs148622636
NM_001040616.3(LINS1):c.718C>T (p.Arg240Trp) rs145145735
NM_001040616.3(LINS1):c.864C>T (p.Thr288=) rs150775570

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.