Variants in gene LMNA with conflicting interpretations "pathogenic" and "uncertain significance"

Submission 1 (pathogenic) minimum review status:		Submission 1 (pathogenic) method:
Submission 2 (uncertain significance) minimum review status:		Submission 2 (uncertain significance) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 15

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HGVS	dbSNP	gnomAD frequency
NM_170707.4(LMNA):c.1634G>A (p.Arg545His)	rs142191737	0.00025
NM_170707.4(LMNA):c.1718C>T (p.Ser573Leu)	rs60890628	0.00011
NM_170707.4(LMNA):c.1580G>A (p.Arg527His)	rs57520892	0.00004
NM_170707.4(LMNA):c.992G>A (p.Arg331Gln)	rs59301204	0.00004
NM_170707.4(LMNA):c.1318G>A (p.Val440Met)	rs121912493	0.00002
NM_170707.4(LMNA):c.1411C>T (p.Arg471Cys)	rs28928902	0.00001
NM_170707.4(LMNA):c.1633C>T (p.Arg545Cys)	rs267607613	0.00001
NM_170707.4(LMNA):c.646C>T (p.Arg216Cys)	rs794728591	0.00001
NM_170707.4(LMNA):c.1003del (p.Arg335fs)	rs1553265660
NM_170707.4(LMNA):c.1130G>T (p.Arg377Leu)	rs61672878
NM_170707.4(LMNA):c.1445G>T (p.Arg482Leu)	rs11575937
NM_170707.4(LMNA):c.1488+1G>A	rs267607640
NM_170707.4(LMNA):c.618C>G (p.Phe206Leu)	rs267607629
NM_170707.4(LMNA):c.694G>A (p.Gly232Arg)	rs267607609
NM_170707.4(LMNA):c.868G>A (p.Glu290Lys)	rs397517912

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